This preprint calls for scientific review, but here’s my takeaway: look closely at your cells (in CellProfiler). If you notice subtle differences, you may have uncovered a phenotype! Massive imaging isn’t just for pretty screensavers, it’s real data waiting to be explored!
15 years in the making, we confirmed that mitochondria -the powerhouse of the cell- have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery...🧵