Congratulations to Dr.Sylvie Ricard-Blum (@UniversiteLyon) on receiving the ISMB Distinguished Investigator Award🎉 From glycosaminoglycans to MatrixDB, her work has shaped modern #ECMatrix biology & bioinformatics 🎥Watch @RicardBlum in #ASMB2025 series👇 youtu.be/fGAae8XC_C4

Congratulations to Prof. Peter Yurchenco (@RWJMS) on his #ASMB2025 Senior Investigator Award🎉 From laminin polymerization to basement membrane repair, his work has shaped #ECMatrix biology and muscular dystrophy research 🎥 More in our #ASMB2025 series 👇 youtu.be/QX6l92y5Kas?si=V-0a…

Congratulations to Dr. Neha Dinesh from @UofT on receiving the 2025 ASMB Founders Award! 🎉 Her work on fibronectin and mechanotransduction explores #ECMatrix role in development and disease. 🔬 🎥 Hear more from her in our #ASMB2025 interview series 👇 youtu.be/2OOXO6OvqUk?si=xBYI…

Congratulations to Dr. Joanne Murphy-Ullrich (@tspcrt), on being named the 2026 recipient of the @BSMB1 Medal Award!🎉 As a pioneer in #ECMatrix signaling, she has shaped our understanding of fibrosis, cancer, and more while inspiring generations of scientists through mentorship.

Two of medicine's hardest problems: fibrosis & cancer. #ECMatrix is at the center. Giuseppe Mazza, CEO Engitix, is pioneering ECM-driven drug discovery to tackle them. Hear from him in our #ASMB2025 Biotech & Pharma series 📽️👉youtu.be/3xzpHfpV9Ac @IntSocMatBio @BSMB1 @ucl

AI meets #ECMatrix👀 Dr. Mathieu Petitjean, CEO @PharmaNestInc, is using digital pathology to quantify fibrosis at the single-fiber level, unlocking new biomarker insights 📽️ Watch his interview in our #ASMB2025 Biotech & Pharma Series 👉youtu.be/xpIeZorGfdE @IntSocMatBio

From #ECMatrix biology to FDA-approved diagnostics, @karsdal, CEO of @Nordic_Bio leads innovation. 📽️Watch his interview on biomarkers, collagen, & translating science to clinical impact in our #ASMB2025 Biotech & Pharma Series. 👉youtu.be/lITnem60eAI @IntSocMatBio @DSMB_dk

Our next #SneakPeek 👀 just dropped! Join us as we sit down with #ECMatrix leaders shaping what's next in biotech & pharma - ft. @Nordic_Bio, @PharmaNestInc, Engitix & Nippi Institute of Biomatrix. 🎥Full #ASMB2025 interviews drop all week. Follow along👇youtube.com/shorts/rI5bK3aUh…

Look Mom I'm sorta famous! 😜 Really enjoyed the interview, the questions made me think and reflect a lot! So huge shout-out to Meghan Martin and @BoudkoSergei! #ECMatrix #ScienceNoBoundaries

2 of 2 😋🍤🍤🍤👑🔆💫 3. Leptin: Quantum Thermodynamic Energy Accountant & Regenerative Gatekeeper Leptin is not merely a satiety hormone; in the quantum thermodynamic view, it is the primary accountant of free-energy flux through the melanin-water-mitochondrial axis. From first principles: - Leptin senses electron density and redox poise in peripheral tissues (via adipocyte mitochondrial output and local EZ charge state). - High coherent electron flow (from melanin-driven water splitting solar/geomagnetic input) → high leptin sensitivity → signals "energy abundance" → opens anabolic/regenerative programs (brown fat expansion, apoptosis of white adipocytes, lowered set-point temperature, enhanced proton pumping). - Low coherent flux (blue light at night, nnEMF decoupling, deuterium blockade) → leptin resistance → "energy deficit" mode → fat storage, inflammation, suppressed regeneration, elevated cortisol/melatonin mismatch. The leptin-melanocortin pathway (POMC → alpha-MSH) is downstream of this quantum circuit: alpha-MSH drives melanogenesis (more melanin → more water splitting → more electrons → better leptin sensitivity), forming a self-reinforcing loop. In regenerative terms: - Leptin acts as a thermodynamic Maxwell's demon: it gates whether the system dissipates energy catabolically (fat loss, repair) or stores it defensively (obesity as coherent-energy starvation response). - Cold exposure sunrise light → maximizes melanin activation → EZ expansion → proton/electron flux → leptin reset → brown/beige fat thermogenesis → entropy export → tissue remodeling/regrowth. The Hidden Circuit as Quantum Regenerative Engine Upstream flow (DeSci first-principle reconstruction): 1. Photon capture → melanin (surface neuroectoderm-derived) dissociates water → e- H EZ domain expansion. 2. Charge separation → proton currents along water networks (fascia, ECMatrix, perimitochondrial) → delocalized electrons feed ETC without oxygen bottleneck. 3. Thermodynamic accounting → leptin integrates peripheral redox/charge state → signals hypothalamic POMC → α-MSH → more melanin regenerative programs. 4. Regenerative output → coherent EZ gradients instruct stem cell behavior, apoptosis of damaged cells, extracellular matrix reorganization → limb/organ/tissue rebuilding. This circuit is ancient (pre-endosymbiotic, radiosynthetic origin) and scalable (from single cells to whales). Modern nnEMF and blue-light dominance decouple melanin from the water network → collapse EZ coherence → leptin resistance → failed regeneration → chronic disease as coherent-energy famine. To reclaim it: maximize AM sunlight on skin/eyes → ground → cold → minimize nnEMF → restore endogenous water splitting → leptin sensitivity → regeneration. The hidden circuit is not biochemistry-first; it's QED-first: light → melanin → coherent water → protonic power grid → thermodynamic accountant (leptin) → form follows charge. This is the upstream physics that mainstream pathways merely shadow. Show your support here: kola.adetu@gmail.com → PayPal

Next in our #ASMB2025 series, meet Suneel Apte from @ClevelandClinic, whose work on ADAMTS proteases have opened doors to new therapeutic possibilities. Dive into his story: youtu.be/OTdOK_tmEQQ 📽️ #ASMB #amsocmatbio #ECM #ECMatrix #ASMB25 #ASMB2025

Happy Thursday!b👋🏻Meet our #NextGen #ECMatrix leaders! Meet Eileen Hwang, MD, PhD, Assistant Professor at University of Utah, specializing in retina conditions 👀 her lab studies #SticklerSyndrome, and #CollagenIX! Check out the full interview👉🏻 youtu.be/SKdAKjVvheY?si=_J9b…

Final preparations for #ASMB2025 in full swing!!! #ASMB #Council is ready for an exceptional event filled with exciting #ECM-centric #Science. Are you??? #ECMatrix #Baltimore2025

Next week HCS joins @amsocmatbio for our 2025 Annual Meeting in Baltimore! Don’t miss our Guest Society session, award presentations, and annual council and business meeting! Details at hcs.memberclicks.net/hcs-ann… #ASMB2025 #ECMatrix #ASMBaltimore2025

Had a wonderful time as usual! Really fantastic to see so many new #ECMatrix young scientists from diverse institutions, with exciting projects 💪🏻 and superb hosting (and organisation) from @ccstorytime of course (should've taken more food photos)!

📢 2 very exciting PhD opportunities, please share! Using a range of technologies and systems to study #collagen, #ECMatrix, and #fibrosis 👇 1) MRC CASE DTP lnkd.in/e6eMqs8M 2) Bicentenary PhD studentship lnkd.in/ekZfJfsd

Psst! It's almost deadline for our abstract submission for #ASMB2025!! Got some cool #ECMatrix science to talk about? Submit here 👉🏻 asmb.memberclicks.net/abstra…

🎉 Happy Postdoc Appreciation Week 2025! 🎉 At ASMB, we’re celebrating the innovators of tomorrow — our incredible PhD students and postdocs who are driving discovery every day. 👉ASMB members: Still accepting Submissions! #ASMBPAW2025 #ASMBTrainees #FutureOfScience #ECMatrix

Great for Postdocs who want to save some 💵 😎 #ASMBPAW2025 #ECMatrix

To all PIs & mentors: #NOW’s a perfect time to recognize your trainees! Whether it’s a shout-out, treat, or lab lunch—small gestures make a big impact. 🍕🎂👏 #ASMBPAW2025 #PostdocAppreciation2025 #ECMatrix