Introducing SoidSMART 🔗 pharmadem.in ✉️ enquiry@pharmadem.in #Pharma #API #DrugDevelopment #PharmaceuticalIndustry #PharmaR&D #AIinPharma #AIML #FormulationDevelopment #SolidStateChemistry #LifeSciences #DigitalChemistry #Innovation #FutureOfPharma

Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo) 1. This paper introduces ExPreSo, a machine learning-driven platform designed to accelerate the selection of excipients for biopharmaceutical formulation development by predicting suitable inactive ingredients based on protein drug properties and product characteristics. 2. ExPreSo uses a dataset of over 350 peptide/protein drug formulations with proven long-term stability, and employs supervised machine learning to predict the presence of excipients, achieving high prediction accuracy for nine prevalent excipients. 3. The model was trained using various features, including protein structural properties and sequence embeddings, and it showed strong predictive power for excipients like acetic acid, histidine, and polysorbate 80, outperforms random predictors with AUCs above 0.7. 4. One of the most impressive aspects of ExPreSo is its speed. The "Fast" version of the model, which uses sequence-based input features, produces predictions in seconds while maintaining comparable predictive performance to slower models that rely on molecular modeling. 5. ExPreSo’s robustness was demonstrated across different formulations and excipient types, with high resilience against biases from platform formulations, proving its utility for excipient selection in both new drug products and reformulations. 6. The system’s ability to predict excipients based on protein sequence data alone, without relying on proprietary formulation details, positions ExPreSo as a versatile and scalable tool for formulation development across the biopharmaceutical industry. 7. The paper emphasizes that ExPreSo’s predictions should serve as a guide for experimental formulation development, helping to reduce the time, costs, and risks associated with excipient screening. 📜Paper: biorxiv.org/content/10.1101/… #MachineLearning #Biopharmaceuticals #DrugFormulation #AIinPharma #Excipients #Biotech #ProteinTherapeutics #DeepLearning #PharmaceuticalResearch #FormulationDevelopment

Tired of struggling with hydrophopic small molecules in product development? We have the solution! ✅ Have a look at our latest #Marinosolv® technology #whitepaper: solv4u.com/fileadmin/01_Mari… Contact our #Solv4U team at bd@marinomed.com. #formulationdevelopment #oceanofideas

Our #USFDA-approved oral solid dosage form manufacturing facility supports process-development, scale-up & clinical supply (Phase 1 to Phase 3 for NDAs) & registration batches for ANDAs manufacturing of oral solid dosage forms. #FormulationDevelopment #CPHIJapan #Biopharma 4/4

In #FormulationDevelopment services, we provide oral solid, liquid, nasal & topical dosage forms for both human & #animalhealth. Our integrated services range from conventional formulations to enabled formulations & complex generic formulations at the lab stage & GMP scale. 3/4

#CPHIJapan2024 is only one day away, and we cannot wait to meet you. Meet with our team to discuss how Syngene can help you in your development & manufacturing programs. Book a meeting with our experts, write to us👉 bdc@syngeneintl.com #FormulationDevelopment #Biopharma 1/4

Our CEO @claire6thompson is attending Swiss Biotech Day, the premier #biotech conference in Europe, on 22-23 April in Basel, Switzerland. Grab her for a chat about #FormulationDevelopment, #SmallMolecules and #Peptides! swissbiotechday.ch/ #FutureproofFormulationsFast

Ever wondered how we tame your badly-behaved #molecules into smart #formulations? Take a #VirtualTour of the labs at our #Formulation facility and see the Agility #DreamTeam in action! agilitylifesciences.com/ #FutureproofFormulationsFast #FormulationDevelopment @PioneerGrp

We are looking for a seasoned formulations leader to play a pivotal role in developing LNPs for multiple programs in Cell & Gene Therapy. Apply below or reach out to Stratacuity at 603-766-0600. stratacuity.com/job/2015084_… #manufacturingjobs #formulationdevelopment #norest

Bragging on the Formulation Automation/HTE & Formulation Tech teams @CortevaUS both phenomenal technically & all around awesome people 👏Cheers to a great year! THANK YOU for everything you do! #TogetherWeGrow #HTE #TogetherWeAutomate #formulationdevelopment #appreciationpost

Introducing Simcyp™ Biopharmaceutics, a game-changer for biopharmaceutical, formulation, and CMC scientists! ow.ly/os0V50Qbvpk #DrugDevelopment #Innovation #FormulationDevelopment

We are pleased to announce the newest member of the Agility tribe, #BusinessDevelopment Director, Lynne Trowbridge. Lynne will be driving the #marketing and business development activities. #FormulationDevelopment #FutureproofFormulationsFast

Using #cyclodextrin to formulate #cannabinoids is more common and handy than you would think. In this short deck we are picking your brain with some potential applications. #formulationdevelopment linkedin.com/posts/carbohyde…

Here comes my reflective limerick! Our tablets showed beautiful sustained release profiles, Which made our delighted clients beam with smiles, Jasper dressed up so sweet, He'll do a trick for a treat, Chatted to Lesley after what's been quite a while. #FormulationDevelopment

Time flies when you are surrounded by a wonderful Tribe. Thanks to everyone who has helped us to get here. Here's to many more years! #DreamTeam #FormulationDevelopment

Sequential offers a full end-to-end platform from study design, recruitment and testing, to analysis, and support on #formulationdevelopment and certification. Join Oliver as he explores how to access clinical studies, #microbiomeformulations, and claims substantiation.

Announcement: New collaborative services agreement We are delighted to announce that we have entered into a collaborative services agreement with @Agility Life Sciences Limited. Find out more on our website: bit.ly/3OAw8IH #FormulationDevelopment #Assays #CellAssays

This week's Cyclodextrin Tales is a brief summary about the techniques used to make cyclodextrin complexes. #formulationdevelopment #cyclodextrin #drugdelivery linkedin.com/pulse/art-cyclo…

#FDDConclave 2023 #Synovaticindia #Hyderabad #summit2023 #formulationdevelopment #drugdelivery #conclave #team #india Ritika Kumar I Synovatic India Machinery Pvt. Ltd. | Synovatic India- Team

I am happy to share that I recently had the opportunity to present my Ph.D. project at the SETU postgraduate conference at the Carlow Campus. #drugdelivery #covid19 #formulationdevelopment #nanoparticles