CELL-FREE SYNTHETIC BIOLOGY
On biochemical constructors and synthetic cells
“Is it possible to build life? More specifically, is it possible to create a living synthetic cell from inanimate building blocks? This question precipitated into one of the most significant grand challenges in biochemistry and synthetic biology, with several large research consortia forming around this endeavour in Europe (European Synthetic Cell Initiative), the USA (Build-a-Cell Initiative) and Japan (Japanese Society for Cell Synthesis Research).”
royalsocietypublishing.org/d…
SYNTHETIC BIOLOGY - SEVERAL LARGE RESEARCH CONSORTIA
🔺Europe
European Synthetic Cell Initiative (SynCellEU)
The European Synthetic Cell Initiative is a formal partnership between research institutions from the Netherlands, Germany, France, and Spain.
SynCellEU consists of a network of excellent European research laboratories, institutions and companies, coordinated by Delft University of Technology (TU Delft) in the Netherlands, that have joined forces to collaborate on synthetic cell research and accelerate its translation into technology.
syntheticcell.eu/
🔸Signing of a Memorandum of Understanding (MOU) between the partners of the European Synthetic Cell Initiative
syntheticcell.eu/signing-of-…
CONTRIBUTING PARTNERS
▪️Delft University of Technology (TU Delft) in the Netherlands, which coordinates the initiative
tudelft.nl/
— DUTCH HUB of SynCellEU
BaSyC (Building a Synthetic Cell) is a research programme aimed at creating an autonomous, self-reproducing synthetic cell with a bottom-up approach, that is, through integration of molecular building blocks. The project is a joint effort of 17 team-leaders with backgrounds in physics, chemistry and biology. They work for 6 Dutch research institutions: Delft University of Technology, Groningen University, Radboud University Nijmegen, Vrije Universiteit Amsterdam, Wageningen University and the AMOLF Institute.
basyc.nl/
— Evolving life from non life (EVOLF)
The EVOLF consortium of 31 scientist leaders with over a 100 PhD students and postdocs is unique worldwide in its top quality and high diversity. EVOLF involves the next generation of top scientists to ensure a continued leading role of the Netherlands in the rapidly developing global field of synthetic cell research & technology.
evolf.life/
▪️The Max Planck Society (MPG) in Germany
mpg.de/en
— MaxSynBio - Max Planck Research Network in Synthetic Biology
maxsynbio.mpg.de/13480/maxsy…
▪️The French Alternative Energies and Atomic Energy Commission (CEA)
The CEA boasts 9 research centres across France. It has built strong partnerships with many other research organisations, regional authorities and universities.
The CEA features four operational divisions tasked with carrying out its research:
Energy Division
Military Applications Division
Technological Research Division
Fundamental Research Division
cea.fr/english/Pages/Welcome…
▪️The Spanish National Research Council (CSIC)
A State Agency for scientific research and technological development, with a special legal status, its own assets and treasury, functional and managerial autonomy, full legal capacity and of unlimited duration (art. 1 Statutes – Articles of Association).
csic.es/en/csic
ASSOCIATE PARTNERS
▪️The University of Oxford in the UK
ox.ac.uk/
— SIGSYNCELL
Part of the broader European synthetic cells consortium SynCellEU
The SIGSYNCELL doctoral network, which is under CNRS coordination, brings together a dozen European academic partners, with twelve PhDs. Together they will explore topics relating to communication within synthetic cells.
cnrs.fr/en/update/sigsyncell…