🚨 Masterclass on management of colorectal neuroendocrine tumors (well-differentiated) by Dr Jen Chan at #GI25 🌎 rising incidence, primarily driven by rectal NETs 📌 most CR NETs are non functional ‼️Grade, size and depth of invasion are some high risk features pre-resection. 💡 EUS important for staging rectal NETs. 📌 Localized rectal NETs: -rectal NET/s <10 mm- endoscopic resection -10-20 mm: Multi-D discussion ->20 mm or LN rectal NETs- LAR or APR -R1 resections are common, consider repeat EUS and multi-D discussion for residual disease management. 📌 Advanced colorectal NETs: -multi-D eval key! -If SSTR , start with SSA (a good test of biology) -following progression- RLT, mTOR inh, TKIs. CAPTEM for G3 -can consider upfront RLT in Ki67 10-55% in select patients based on NETTER-2 #NETsatGI25 @ASCO

In line with my #NETsatGI25 agenda, I want to thank @OncBrothers for covering the paradigm of NEN therapies at their fantastic event last night. 🦓 #GI25 STARTER-NET doesn’t change practice but there’re a lot of newer and upcoming therapies and trials that will change how we treat NETs and give us better options to offer to our patients. @NANETS1 @LACNETS

#NETsatGI25 🦓 🎗️

Im bummed that my mentor @ChandrikhaC is not at #GI25 to cheer me on, but excited to present our analysis on (well-differentiated) early-onset small bowel NETs. #NETsatGI25 Poster board F13 Excited to build upon the evolving understanding of early-onset NENs. There’s a lot of work that needs to be done. More to come from @UIowaCancer Cc: @SempriniJason

As a NET patient and admirer of the work you both do to treat, inform, and promote the NEN community, I’ll gladly post #NETsatGI25. NEN is not a rare cancer type - pay closer attention please, @ASCO!

Such a pleasure to connect with @JaydiDelRivero on the sidelines of #GI25 Thanks for all your valuable guidance and feedback! Maybe we need a new hashtag for #NETsatGI25 to send across a message @ASCO 🦓 🎗️