22 Jun 2025
3D reconstruction of a 3-day-old zebrafish heart beating. Credit to Dr. Michael Weber (@openspim). For those interested, you can read more about the acquisition and post-processing here: nature.com/articles/nmeth.30โฆ #ZebrafishZunday
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6 Mar 2024
๐ฌ Despite the impact, limited access to costly instruments hinders progress.
#OpenSource initiatives like openSPIM and OpenFlexure aim to democratize technology, but integrative systems are crucial for collaborative innovation.
๐ nature.com/articles/s41467-0โฆ via @NatureComms
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ืื ืืืฉืจืื ืืฉ ืคืืืช ืืกืฃ ืืื ืื ืกืื ืืืกืื. ืืื ืืงืืืื ืืืืื ืื ืืืกืืื ืืืื ืืื.
ืืขืืื ืืืืงืจืืกืงืืคืื ืืฉ ืืืืืื ืืช openSPIM
openspim.org/
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26 Sep 2023
We spy a beautiful two-chambered fish heart ๐ Congrats, Dr. Michael Weber @openspim!
26 Sep 2023
The wait is over! The winners of the 2023 #NikonSmallWorldInMotion competition have been revealed. Check out the full video gallery here: bit.ly/3t8y9VA
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30 May 2023
Very interesting! I wonder why you need a light sheet instead of a normal wide field fluorescence mic?
We are using an OpenSPIM in combination with sample immobilization in a gel to quantify small fluorescent particles in a volume.
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18 May 2023
Come over and learn that my haircut hasn't improve much since this photo was taken - 6 years ago ๐ Anyway, let's build some #matchboxscopes and image some @ZebrafishRock's with the @openspim inspired @OpenUc2-based #lightsheet.
18 May 2023
Building a microscope is simple โ They said. Tomorrow our Seminar Series welcomes @beniroquai who is leading a hands-on session tomorrow @SussexUni teaching us how to build our own 5$ cloud-connected microcontroller-based microscope. #neuroscience #futurefridays
ALT Benedict Diederich, Leibniz-IPHT Jena, Germany.
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10 May 2023
Prof Dag Kristian Dysthe demonstrating his openSPIM in the first day lab session of #10thNorMIC workshop. And on the same day, Dag Kristian was awarded the Education price in UiO. @unioslo_mn @biovitenskap @NCMMnews uio.no/om/aktuelt/aktuelle-sโฆ
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7 May 2023
3D reconstruction of a 3-day-old zebrafish heart beating. Credit to Michael Weber @openspim. #ZebrafishZunday
Evident Life Science
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19 Apr 2023
Last week I had the privilege of visiting the amazing facilities of @mpicbg, including a sneak peek of their OpenSPIM. Many thanks to my excellent guides @PavelTomancak and Jan Peychl! #lightsheet #microscopy
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31 Dec 2022
Please post here as well, that's very interesting ๐คฏ
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30 Dec 2022
put them in straight metal tubes and stick them in autoclave , worked for us. Tested by Gloria Slattum back in @huiskenlab .
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29 Dec 2022
Asking for a friend: Static/Straight/non-bendable FEP tubes for #lightsheet microscopy - is this a thing? Or DIY-only? CC: @ReynaudEmmanuel @openspim @huiskenlab
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21 Dec 2022
๐จ๐จ @OpenUC2 module alert!๐จ๐จ A compact motorized XYZ stage with (sub-)micrometre motion using low-cost off-the-shelf components. Useful for: light-sheet sample handling. Similar to the @openspim drives, but open-source :-) github.com/openUC2/UC2-Motorโฆ FW: github.com/youseetoo/uc2-espโฆ
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18 Dec 2022
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18 Dec 2022
This is very true, both projects are looking at different scales.
OpenSPIM is for living objects in the 100um-1mm range, and MesoSPIM is for optically cleared objects in the 1mm-1cm (or even bigger) range.
Apples ๐ and Pears ๐
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8 Dec 2022
Honestly, I am relieved to see that GPT3 is not as smart as everyone else is claiming. ๐
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2 Dec 2022
WTF? Who's ever added a Spinning Disk Confocal scan head to the detection path of a lightsheet, and WHY?
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24 Nov 2022
we concede...LSM has won the show! OPT'rs will just step aside and hibernate.
Seriously, our biggest problem has been keeping up with micromanager updates, and lack of interest in the technique (even commercial)
the #openspim community has done a better job with support. kudos
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