📄 SPOT-MAPPING: combining oedema and scar assessment in a single CMR sequence 🔗 DOI: doi.org/10.1093/ehjimp/qyag0… 🫀 CMR is powerful—but often fragmented: 👉 T2 mapping for oedema 👉 LGE for scar ➡️ Multiple sequences, multiple breath-holds, longer scans This study introduces a potential game changer: SPOT-MAPPING. ✨ What is SPOT-MAPPING? 👉 A novel CMR sequence combining: ✔ T2 mapping (oedema) ✔ Black-blood LGE (scar clarity) ✔ Bright-blood imaging (anatomy) ➡️ All in a single, co-registered acquisition 📊 As illustrated in the graphical abstract (page 2): 👉 simultaneous visualization of oedema scar anatomy ✨ Key findings: ⏱️ Acquisition time ↓ by ~50% ➡️ ~6 min vs ~12 min with conventional sequences 📈 Excellent agreement with reference techniques: ✔ LV mass (ICC ≥ 0.93) ✔ Scar quantification (minimal bias) ✔ T2 values (no significant difference in oedematous myocardium) 🧠 Why this matters: 👉 Traditional workflows: ❗ multiple breath-holds ❗ misaligned datasets ❗ time-consuming analysis 👉 SPOT-MAPPING: ✔ perfectly co-registered data ✔ faster workflow ✔ improved patient comfort 📊 Added clinical value: 👉 Enables simultaneous assessment of: oedema vs irreversible injury scar transmurality microvascular obstruction / IMH ➡️ Particularly relevant in acute MI and complex cardiomyopathies ⚠️ Important nuance: 👉 Slight overestimation of T2 values vs reference 👉 Requires validation in larger cohorts 💡 Clinical take-home message: 👉 SPOT-MAPPING simplifies CMR without compromising accuracy ➡️ From multiple sequences → one integrated acquisition 👉 A step toward: ✔ faster scans ✔ standardized workflows ✔ more scalable CMR 🚨 Bottom line: One scan, multiple insights—SPOT-MAPPING may redefine how we acquire and interpret CMR. #Cardiology #CMR #CardiacImaging #T2Mapping #LGE #MyocardialInfarction #AIinMedicine #MedTech #PrecisionMedicine 🫀📊

📄 Ischaemia–reperfusion injury: new insights from quantitative CMR 🔗 DOI: doi.org/10.1093/ehjimp/qyaf1… 🫀 Reperfusion saves myocardium—but it can also cause additional injury. This experimental CMR study provides high-resolution, time-resolved insights into what really happens in the myocardium during ischaemia and early reperfusion. ✨ Study design: 🔹 Swine model of acute MI (LAD occlusion → reperfusion) 🔹 Continuous CMR acquisition at: baseline during ischaemia immediately after reperfusion up to 2–3 hours 🔹 Quantitative T1 & T2 mapping pixel-wise analysis ✨ Key findings: 📈 During ischaemia: ➡️ Moderate increase in T1 and T2 ( ~11%) 👉 reflecting early oedema 📈 After reperfusion: ➡️ Marked increase in T1 and T2 ( ~23%) 👉 indicating rapid and significant tissue water accumulation 📊 Critical insight: 👉 The biggest myocardial change happens AFTER reperfusion ➡️ Not during ischaemia ➡️ But immediately after restoring flow 🧠 Three distinct reperfusion patterns identified: 1️⃣ Reperfusion MVO (microvascular obstruction) 👉 severe injury, largest signal increase 2️⃣ Reperfusion without MVO 👉 less severe but still significant oedema 3️⃣ No effective reperfusion 👉 blunted signal changes 📌 As shown in Figures 2–4 (page 5), each pattern has distinct T1/T2 evolution profiles ⚠️ Key paradigm shift: 👉 Post-reperfusion oedema: ❗ does NOT reflect pre-ischaemic tissue status ❗ does NOT predict final tissue outcome ➡️ Early imaging interpretation may be misleading 🤖 Methodological innovation: ✔ Pixel-wise standardised analysis ✔ Eliminates ROI bias ✔ Enables true spatial and temporal mapping of injury 💡 Clinical implications: 👉 Reperfusion injury is: dynamic, heterogeneous, and not fully captured by traditional imaging timing 👉 Timing of CMR matters: ➡️ early post-reperfusion scans may reflect transient inflammation, not final infarct size 🚨 Bottom line: In acute MI, the most dramatic myocardial changes occur after reperfusion—not during ischaemia—and early oedema does not define final injury. #Cardiology #CMR #MyocardialInfarction #ReperfusionInjury #T1Mapping #T2Mapping #CardiacImaging #PrecisionMedicine #TranslationalResearch 🫀📊

🫀📊 New in JACC: Advances: Routine CMR T2 mapping can noninvasively estimate mixed venous O₂ saturation and independently predict mortality & HF hospitalization. A promising step toward practical, noninvasive hemodynamic assessment in HF. 🔗loom.ly/ajvcfLA #HeartFailure #CardiacMRI #T2Mapping #Hemodynamics

#EHJIMP What's your possible diagnosis in a patient with #chestpain, raised #troponin and normal #coronary_angiography? Can you see the difference between #SPOT and #PSIR and #T2mapping sequences? doi.org/10.1093/ehjimp/qyaf1… @JGrapsa @alessia_gimelli @EHJIMPEiC @pabloplopez_

📢 #SpecialIssue Cardiac Imaging and Heart Diseases: Recent Progress 📅 30 May 2026 👨‍🔬 Guest Editor: Dr. Francesco Secchi from University of Milan, Italy 🔗 mdpi.com/journal/applsci/spe… #cardiacimaging #cardiovascularMRI #cardiacCT #4DFlowMRI #T1mapping #T2mapping #lateenhancementCT #fractionalflowreserve #FFRCT #artificialintelligenceincardiacimaging #machinelearningincardiology #radiomics #3Dimaging #hybridimaging #perfusionimaging #motionanalysis #automatedsegmentation #deeplearningforcardiacdiagnosis #functionalassessment #prognosticevaluation #bigdataincardiovascularimaging #automatedimageprocessing #clinicalimpactofimagingtechnologies #cardiovasculardiseasediagnosis

心筋梗塞の時の非梗塞心筋におけるT2mappingの意義。同様のことはT1もECVも報告あります。加えて心筋梗塞後の何日目に撮るかは重要です。

#CMRcafe 第三段のラストはストレインとT1/T2mappingを鍋田先生@nebetake と基本をおさらいしつつ、臨床に即して考えたいと思います。1/24 20時よろしくお願いします。

今回の話にはありませんでしたが，これらに加えて 「冠動脈CTみたいなMRCA」 「負荷心筋シンチみたいな負荷perfusion」 「T1/T2mapping」 など，さまざまなシークエンスの情報を追加できます しかも非侵襲的に 心エコー＋Gaシンチ＋病理 って考えただけでもワクワクしませんか？

Wie wichtig ist die Früherkennung von Knieknorpelveränderungen im Nachwuchsleistungssport?🏐 Die Ergebnisse der prospektiven #T2Mapping-studie wurden kürzlich veröffentlicht!🤓🎉 @UKL_Leipzig @ThiemeGruppe DOI: 10.1055/a-2081-3245 #Röfo #cartilage #pediatric #volleyball #knee

心臓MRIに関して ✔︎T1(LGE/T1mapping)での非侵襲的心筋障害 ✔︎T2(T2強調画像/T2mapping)での心筋炎症 を組み合わせた改訂版Lake Louise Criteriaが診断に用いられる 発症後2-3週以内の検査を推奨 5/n

Valor pronóstico del #VEC y #T2mapping en Trasplante Cardiaco / ECV & T2 mapping in Heart Transplant @JACCJournals bit.ly/3hCVhjZ @SIAC_cardio @onco_cardiology @purviparwani @LopezOpitz @ecocardio_cl @urmeneta87 @DiegoChango1 @chemaimagencv @HugoMartinezCMR @iamritu

Valor pronóstico del #VEC y #T2mapping en Trasplante Cardiaco / ECV fraction & T2 mapping in Heart Transplant @JACCJournals bit.ly/3hCVhjZ @iamritu @chemaimagencv @onco_cardiology @mariovar55 @SIAC_cardio @purviparwani @LopezOpitz @DrSergioBarros @JournalASEcho

State of the art imaging of the hip, dr. Rajat Chowdhury. The goal is to prevent damage before it's done... So we want to do "functional MRI cartilage assessment". T2mapping, T1ro, DWT/DWI, dGEMRIC, etc. #sportsmedicine #sportsradiology @FortiusClinicUK @FortiusFISIC @AxiomClinic

Memo(for me): @JACCJournals #CMR #T2mapping #IntracardiomyocyteEdema #EarliestMarker #Anthracycline #Cardiotoxicity #CardioOnc Serial Magnetic Resonance Imaging to Identify Early Stages of Anthracy... sciencedirect.com/science/ar… #CardioJapan

T2 relaxation time mapping can be a potential biomarker for cartilage deterioration. Changes in these times can be the result of changes in hydration or disruptions in the network of collagen. T2 maps are acquired by performing a spin echo based multi-echo acquisition #T2mapping

How reliable is T2 mapping? We’re looking into the reliability and clinical consequences of T2 mapping results in #cartilage surgery patients. To be continued... @CartilageRepair #t2mapping

Reduction of Global Longitudinal Strain (GLS) in echo is an early sign of chemotherapy toxicity, before EF goes down. Garan-Ariola et al now show in 20 pigs that myocardial edema seen by CMR T2mapping may be the earliest sign. onlinejacc.org/content/73/7/…. #cardiotwitter @escardio

Really interesting paper on #CMR in #CardioOncology - does #T2mapping have a key role to play in detecting #anthracycline #cardiotoxicity? Well done to @cgalanarriola and colleagues! onlinejacc.org/content/73/7/…

T2 relaxation time mapping has shown to be a potential biomarker for cartilage deterioration. T2 maps are acquired by performing a spin echo based multi-echo acquisition. #imagingU, #T2mapping, #CartilageMapping

T2 Mapping (TR 1500, TE range -8 to -64) Articular cartilage of acetabular roof thicker at lateral acetabular rim. Fibrocartilaginous labrum included in thresholding of TE values StollerMSKcourse.com #StollerMSKcourse #TheHip #T2Mapping #MRI #orthopaedics #sportsmedicine