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a lot of people just do apt install apache2 or apt install nginx both are bad use you're own webserver in #golang will remove bottleneck will be able to handle way more requests and connections
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Replying to @RoundtableSpace
bottleneck will be the webserver or the webserver backend code i suggest #golang
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update on #FIR0432 - this is a case of organized cybercrime that Tekzilver has been fighting since 2021 - @Uppolice is literally sitting on all kinds of evidence we submitted: including Apache webserver logs, IP addresses (thousands of them), email ids, host IP addresses, hosting history, DNS history and more - there is a report from @IndianCERT regarding the incident. - @Uppolice officials are CLEARLY INVOLVED. they're ignoring the evidence, protecting the accused and submitting fake reports. - @UPGovt is just sitting out there doing nothing. the police officers they appointed in their cybercrime police force - have ZERO knowledge of computers. UP cyber cops don't know shit about anything cyber. - no court hearing this year so far. the last court hearing was in Nov 2025! - THE NEXT COURT HEARING IS ON MONDAY, 15 JUNE 2026 - in the next few days, Tekzilver will be approaching higher courts in the country against not just the criminals, but against the cops & UP state government. stay tuned. @myogiadityanath @narendramodi @AmitShah @AshwiniVaishnaw @MeityGov @CBIHeadquarters @NIA_India @dgpup
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Jeffrey Scott Holland retweeted
#FM #BCL アフリカ大陸2つ目のFM-DX Webserverが立ち上がりました。 ブルキナファソです。 多くのフランス語FMのスペクトルが立っています!
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Modstrings Classes for DNA & RNA sequences containing modified nucleotides bioconductor.statistik.tu-do… ModRNAString alphabet Alphabet for the modifications used in this package are based on the compilation of RNA modifications by the Bujnicki lab (Boccaletto et al. 2018). The alphabet was modified to remove some incompatible characters bioconductor.statistik.tu-do… MODOMICS modomics.genesilico.pl/ MODOMICS was linked to RNAcentral, a DB of non-coding RNA sequences, & serves as a source of modified tRNA & rRNA sequences Many of the products of modification reactions are substrates for further reactions, & the formation of hypermodified residues occurs in complex pathways, which are displayed as graphs in the PATHWAYS section of the database academic.oup.com/nar/article… RNAcentral: non-coding RNA sequence database rnacentral.org/ RNAcentral is a free, public resource that offers integrated access to a comprehensive & up-to-date set of non-coding RNA sequences provided by a collaborating group of Expert Databases representing a broad range of organisms & RNA types academic.oup.com/nar/article… RNAcentral Expert Databases Currently the RNAcentral Consortium is formed by 62 Expert Databases, 52 of which have already been imported into RNAcentral rnacentral.org/expert-databa… RNAcentral assigns unique IDs to every distinct sequence & supports species-specific identifiers for referring to sequences in specific organisms rnacentral.org/help#rnacentr… The sequences are mapped to reference genomes from more than 250 species using blat. U can use a genome browser to browse all mapped sequences, view individual sequences in their genomic context, or d/l genome coordinates in several formats rnacentral.org/help/genomic-… We import modified nucleotides from Modomics & PDB, miRNA targets from TarBase, & Gene Ontology annotations from QuickGO. All sequences are annotated w/ Rfam models to provide warnings & additional info. The sequence & structural info is used to build Infernal covariance models, which can be used to find new instances of RNA families & annotate genomes w/non-coding RNAs rnacentral.org/help/qc We also provide secondary structure diagrams for a wide range of RNA types rnacentral.org/help/secondar… HMMER - biological sequence analysis using profile hidden Markov models (HMMs) HMMER searches bio sequence databases for homologous sequences, using either single sequences or multiple sequence alignments as queries. HMMER implements a tech called "profile hidden Markov models" github.com/EddyRivasLab/hmme… HMMER is often used together w/ a profile database, such as Pfam (pfam.xfam.org/) or many of the databases that participate in Interpro (ebi.ac.uk/interpro/) HMMER can also work w/ query sequences, not just profiles, just like BLAST. For example, u can search a protein query sequence against a database w/ phmmer, or do an iterative search w/ jackhmmer HMMER is designed to detect remote homologs as sensitively as possible, relying on the strength of its underlying probability models. In the past, this strength came @ significant computational expense, but as of the new HMMER3 project, HMMER is now essentially as fast as BLAST hmmer.org/ We believe HMMER compiles & runs on any POSIX-compliant system w/ an ANSI C99 compiler, including Mac OS/X, Linux, & any UNIX operating systems, provided it supports SSE2, ARM NEON, or big-endian Altivec/VMX vector instructions. This includes essentially all Intel/AMD compatible machines, Apple OS/X Intel or ARM machines, & some PowerPC machines hmmer.org/documentation.html HMMER Webserver ebi.ac.uk/Tools/hmmer/home HMMER User’s Guide V.3.4 eddylab.org/software/hmmer/U… Easel - C library for bio sequence analysis Easel, used by HMMER & Infernal, supports our work on computational analysis of bio sequences using probabilistic models. Easel aims to make similar apps more robust & easier to develop, by providing a set of reusable, documented, & well-tested functions github.com/EddyRivasLab/ease…
Presence of group II introns in phage genomes Advances in RNA structure-based homology searches using covariance models has provided the ability to identify the conserved secondary structures of group II introns. Here, we discover that group II introns are widely found in phages from diverse phylogenetic backgrounds, from endosymbiont phage to jumbophage. A general computational method for identifying homologs of a conserved RNA secondary structure and sequence consensus uses probability models called profile stochastic context-free grammars (profile SCFGs, also called covariance models) [25, 26].academic.oup.com/nar/article… academic.oup.com/nar/article… A software package called Infernal implements profile SCFG-based search and alignment [27].academic.oup.com/bioinformat… The Rfam database of 4000 known conserved RNA structure elements is built with Infernal [28].academic.oup.com/nar/article… The input to an Infernal search is a multiple sequence alignment of the conserved RNA annotated with its consensus secondary structure. From this sequence and structure information, Infernal builds a consensus statistical model, which can then be used to search genome sequences for homologs, and to structurally align new homologs to the consensus. Profile stochastic context-free grammar (SCFG) algorithms used to be prohibitively computationally expensive, but a set of accelerated algorithms in Infernal now allows for comprehensive searches for RNAs in large genome and metagenome datasets, including RNAs the size of catalytic introns [29].academic.oup.com/nar/article… HERE, WE USE INFERNAL TO SEARCH FOR GROUP II INTRONS IN PHAGE GENOMES. academic.oup.com/nar/article… Infernal ("INFERence of RNA ALignment") Infernal ("INFERence of RNA ALignment") is for searching DNA sequence databases for RNA structure and sequence similarities. It is an implementation of a special case of profile stochastic context-free grammars called covariance models (CMs). A CM is like a sequence profile, but it scores a combination of sequence consensus and RNA secondary structure consensus, so in many cases, it is more capable of identifying RNA homologs that conserve their secondary structure more than their primary sequence. eddylab.org/infernal/ The "cmbuild" program builds a statistical profile of your alignment. That covariance model (CM) can be used as a query in a database search to find more homologs of your RNAs (the"cmsearch" program). You can also use a covariance model (CM) of a representative alignment of your sequence family to create a larger consensus alignment of any number of RNAs (the "cmalign" program). eddylab.org/infernal/README.… INFERNAL User’s Guide Sequence analysis using profiles of RNA sequence and secondary structure consensus eddylab.org/infernal/Usergui… Biocontainers wrapper for infernal  quay.io/repository/biocontai… Galaxy wrapper for Infernal prediction tools toolshed.g2.bx.psu.edu/repos… Rfam Rfam is a database of functional non-coding RNA families represented by multiple sequence alignments and consensus secondary structures. rfam.org/ The Rfam database is a collection of non-coding RNA sequence families of structural RNAs, including non-coding RNA genes as well as cis-regulatory elements. Each family is represented by a multiple sequence alignment and a covariance model (CM). docs.rfam.org/en/latest/abou… The Rfam database of RNA families is based on the Infernal software engine. This article demonstrates how to use the Rfam database and website and includes a section on using Infernal for genome annotation. pmc.ncbi.nlm.nih.gov/article…
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Replying to @thdxr @bentlegen
the way I added HTML visualizations was with a .visuals dir in the project folder and a simple webserver that creates a slide deck of html pages from that folder
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But those are only responsible for a subset of the vulnerabilities. If you could eliminate them by using a specific language or tool, there wouldn't be an entire industry built around security. And by the way, he can write a new webserver in Haskell and show us how good that is. Should be easy in the age of AI, shouldn't it?
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Best resource to learn Go HTMX Tmpl Best way is by doing, create a small project like a counter example. 1. Fail faster. 2. If you want to understand a concept gobyexample.com/ and programming-books.io/essenti… is perfect. Go into go docs go.dev/doc/ if you need to scan more in depth. 3. For HTMX the docs are perfect htmx.org/docs/ 4. For templ, same, docs will be perfect. templ.guide/ Try them differently first, then combine. So a basic webserver in go, then use HTMX with it, then clean up route and send templ template instead. I would also recommend using pkg.go.dev/html/template html package as it is pretty much capable without extra package, but it is your choice in the end as you might like templ features or syntax better

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HTTP/2 Bomb – neue DDoS-Attacke gegen Webserver ift.tt/6M0vCUO Ein neuer Denial-of-Service-Angriff – DoS – namens HTTP/2 Bomb zeigt, wie leicht sich Webserver mit wenig Aufwand außer Betrieb setzen lassen. Für Unternehmen ist vor allem wichtig: Schon ein einzelner An…
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Replying to @afosstyle1
We used an in house webserver with proxy/edge servers located worldwide to relay video content.
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V mém malém testu 40 držených streamů přidalo cca 0,9 MB aktivní paměti HAProxy. Tedy zhruba 22 KB na stream. Samo o sobě nic dramatického. Jenže 40 streamů je nic. Běžný notebook zvládne daleko více. A HAProxy není běžný webserver :)
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I know I haven't been very active lately, but I bring you something worth checking out. 👀 The new version of upgopher is out. It is a simple Go file-sharing server, and now it supports uploading entire folders and much better directory navigation.  👇 #go #webserver #upgopher
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Replying to @MadamSavvy
Not in the last 15 years or so, no. I remember doing that in the early 20s to share stuff with friends, befofe it was easy to share files. I stopped when I found out how to spin a local webserver, that'd be around 2008... I still use mailing lists for certain projects though
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Replying to @bigaiguy
"redbean, a complete web server inside a single zip file." I am not sure you understand what you've written. You can put your whole rootfs in a zip file. Redbean is a static binary webserver.
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Pretty Kitty Kate💗 retweeted
Za nejvíce užitečný příklad považuji ukázku 3 různých přístupů, jak na #CircuitPython provozovat ovládací webserver. V popředí s minimalistickým frontendem v Bulma od @jgthms a @Alpine_JS , které pak komunikuje pomocí websocketů nebo SSE - to v praxi používám mnoho let.
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Replying to @OrangeFren
What. He runs the monerod on the webserver!?
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