Filter
Exclude
Time range
-
Near
PromoJack (PJ) retweeted
My sole is your new religion๐Ÿ™Œ.. Drain your wallet in devotion๐Ÿค‘๐Ÿ‘ #FindomWorship #DirtySoles #Drains $aturation $aturday Custom content all day Losers
11
40
1,033
aturation | White gray warm wood | Open floor plan, hidden storage | Clean aesthetic, maximum vibes | What do you think? #MinimalDesign #HomeInspo
7
638
ฮ™f you are a man wanting to improve your fertility, here are some basic things to consider/look into ๐Ÿ‘‡ First, understand that spermatogenesis begins with spermatogonia (stem cells located along the basement membrane of the seminiferous tubules). There are two main types: -Type A (which divide mitotically to maintain the stem cell population) and -Type B (which differentiate to continue the process). Type B spermatogonia undergo mitotic division to produce primary spermatocytes. Each primary spermatocyte then duplicates its DNA during the pre-meiotic S phase, resulting in chromosomes with two sister chromatids, before entering meiosis I. In meiosis I, the homologous chromosomes separate, forming two secondary spermatocytes. These secondary spermatocytes quickly undergo meiosis II, where the sister chromatids separate, yielding four haploid spermatids. The final phase, called spermiogenesis, transforms these spermatids into mature spermatozoa. So there are 3 main stages in spermatogenesis, spermatogonial proliferation, meiosis and spermatid ,aturation. Now, spermatogenesis is driven by 3 main hormones of the hypothalamic-pituitary-gonadal (HPG) axis: -Testosterone -Follicle-stimulating hormone (FSH) -Luteinizing hormone (LH) Here are some more details on this: -Hypothalamus, releases gonadotropin-releasing hormone (GnRH) (a decapeptide synthesized by neurons) in pulses (GnRH is released in discrete bursts every 60-120 minutes, a process thatโ€™s kisspeptin, neurokinin B and dynorphin, besides certain feedback loops (faster pulses favor LH, slower favor FSH). -The pituitary gland releases FSH that drives the initial expansion of spermatogonia (it acts on Sertoli cells in the seminiferous tubules and stimulates them to produce androgen-binding protein (ABP) and secrete inhibin B) and early spermatogenesis (up to spermatocyte stage). It also releases LH that drives testosterone synthesis by stimulating cholesterol uptake and its conversion to testosterone via the steroidogenic acute regulatory protein (StAR) and enzymes like CYP11A1 and 3ฮฒ-HSD in the Leydig cells in the testicular interstitial. -The testes produce testosterone that diffuses into seminiferous tubules, binding androgen receptors (AR) on Sertoli cells. Notes: 1. Sertoli cells are derived from the epithelial cells of the developing testes during embryogenesis, found inside the seminiferous tubules of the testes and form a layer lining the tubules, surrounding and interacting with germ cells (the cells that become sperm). 2. Leydig Cells are located in the interstitial space (the area between the seminiferous tubules) of the testes, produce testosterone under LH control (via cAMP/StAR pathway), diffusing it into the tubules to support Sertoli-germ cell interactions. 3. Germ cells are the precursors that develop into mature sperm. Some basic tests that you can get done to assess your fertility status: -Semen analysis (sperm count, motility and morphology) -Total testosterone -Free testosterone -SHBG -Follicle-stimulating hormone (FSH) -Luteinizing hormone (LH) -Scrotal ultrasound -Genetic testing (a karyotype or Y-chromosome microdeletion test)
Egg freezing costs $15-20k and doesn't guarantee anything. You can invest that same money into optimizing your metabolic health and increase your odds of conceiving naturally by 3-10x. One is a gamble. One is an investment.
1
13
173
28,427
2 Jul 2023
Replying to @jackbutcher
(H)ue (S)aturation (L)light ?
3
234
Sa-a-aturation, when the rain comes sweepin' down the plain and the waving wheat.. is soggy and flattened Su-u-usurration, when the grass whispers gently 'cross the plain and the waving wheat, it sure sounds sweet as it murmurs to itself time and again #artwiculate #susurration
1
4
89
22 Dec 2022
Replying to @md1talk
โ€ข PaO2: (P)artial pressure of O2 in (a)rtery โ€ข SpO2: O2 (S)aturation measured by (p)ulse oximeter โ€ข SaO2: O2 (S)aturation measured by blood gas (a)nalysis โ€ข PAO2: (P)artial pressure of O2 in (A)lveoli
17
353
15,267
18 May 2020
ham wir noch p reamps e qualizer p late reverb s aturation
2
8
O peration Doomsday K RIT Wuz Here D AMN. M advillainy U nderground Kingz S tankonia I llmatic C ollege Dropout R oom25 A trocity Exhibition T PAB I GOR N one Shall Pass G raduation S ATURATION III
12 Jan 2020
H itler Wears Hermes 6 I t Was Written P iรฑata H arlan and Alondra O nly Built 4 Cuban Linx P rhyme F lower Boy I f Youโ€™re Reading This Itโ€™s To Late E nter The Wu-Tang (36 Chambers) N OIR D AYTONA
3
20 Nov 2019
If you're having visibility issues on modern warfare just up your aturation setting on your monitor
1
3
Replying to @JesseLingard
congl;aturation @JesseLingard come back to England all of you @ManUtd town and win 3 consecutive titles
2
28 Mar 2018
A meteor will be making impact on all ARKpocalypse servers at 2:30pm EST tomorrow (Thursday). At this time the clusters will become barren and ready for a new 30 day experience. ARKpocalypse are special monthly wipe servers with 3x taming, harvest, XP, aturation, hatching more!
55
32
175
A Ph.D allows you: 1. (P)urpose. 2. (I)mpact. 3. (M)aturation 4. (P)romise.
1
1
ATURATION - Kevin and the others Best songs: GOLD, CASH, TRIP, STAR, BOYS, SKIT 3 Worst song: FAKE (it's still a 7) Strong 8 to Light 9
1
Replying to @jstanly11
@jstanly11 @NFL Over$aturation of game$ - A$ a kid it wa$ $unday$ at 12, 3 and $unday night - give it time and we'll have Tue$day day game$
1