1 Jul 2024
Happy Academic New Year from @HopkinsHeme! 🩸🥳🩸
Today we welcome @Hopkins_HemOnc graduate & physician-scientist #complementopathy phenom, Dr. Michael Cole, as a new faculty member of our #HemeDreamTeam!! We are so lucky to have such fabulous faculty.
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2 Apr 2023
A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism ashpublications.org/blood/ar…
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30 Mar 2023
Andersen JF et al, A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood. 2023 PMID: 36947859.
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11 Oct 2022
#TSACOTUESDAYS! 🔥
Complementopathy and coagulopathy occurs early in trauma patients.
What is the interplay between the two cascades?
READ to find out more ➡️ bit.ly/3yy235v
#SoMe4Surgery #TSACOGlobal #Traumatology
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6 May 2021
thrombotic microangiopathies (TMAs: TTP, HUS, etc)
🩸dx TMA based on schistocytes & hemolytic anemia
🩸TMA has a broad ddx (not just TTP vs. non-TTP)
🩸PLASMIC score helps sort who needs plasma xchange
🩸complementopathy = new dimension of critical illness
emcrit.org/ibcc/tma/
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20 Jul 2020
Catastrophic Antiphospholipid Syndrome (CAPS) - fresh @iBookCC chapter
🧢 RARE CAUSE OF MULTI-ORGAN FAILURE
🧢 PERHAPS PRIMARILY A COMPLEMENTOPATHY?
🧢 KNOW THE RED FLAGS TO AVOID MISSING THE DIAGNOSIS 🚩
emcrit.org/ibcc/caps/
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CAPS is a complementopathy. B2GP is homolog to factor H. And there is a treatment!! Eculizumab (anti-C5a) #ACR17
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9 Aug 2017
Every other vasculitis or complementopathy or nephrotic syndrome - we'll try anything there. #nephjc
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