defining pediatric immune health and the mechanisms by which chronic inflammation and immune deficiency disrupt it
Joined September 2019
- Tweets 183
- Following 711
- Followers 812
- Likes 1,182
23 Photos and videos
Pinned Tweet
26 May 2023
Studying human pediatric and mouse IgA deficiency, in collaboration with @LabSilverman, shows increasing exposure of commensal microbes to the systemic immune response yields immune dysregulation -- helping understand why only some IgA deficient patients are symptomatic!
26 May 2023
Deficiency of IgA antibodies influences how well the immune system can maintain control of intestinal bacteria, finds new study involving pediatric patients with varying IgA levels. @henricksonlab @LabSilverman scim.ag/2LQ
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1 Mar 2024
So excited that our paper on preTCRa is out! It was a wonderful experience working with this collaborative, international immunology research team. This story emphasizes how much we can learn from our rare patients—both about new diseases and basic immune mechanisms.
29 Feb 2024
1/ Just in! We report the first humans with inherited pre-TCR⍺ deficiency in @sciencemagazine. Dive into our fascinating findings on complete and partial forms of pre-TCRα deficiencies, including a common variant in the Middle East and South Asia. science.org/doi/10.1126/scie…
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3 Dec 2023
Thanks, I had a great time joining @UPenn_Allergy to discuss the role of genetics in our field!
1 Dec 2023
It was a privilege to welcome @henricksonlab to Grand Rounds today to discuss genetic testing and interpreting variants of uncertain significance. Thank you for providing a very engaging and informative talk on a very important topic! @ChildrensPhila @PennMedicine @AAAAI_org
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17 Oct 2023
Very proud PI! Great job @Jose_S_Campos
17 Oct 2023
@Jose_S_Campos rocks up for @CytokineSociety meeting talking about STAT3 and CD8 dysregulation @IGGPenn
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Sarah Henrickson retweeted
18 Aug 2023
In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance?
Read to find out! In our new work from the @EJohnWherry lab, out now at @SciImmunology, we...
bit.ly/45yOFMB
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Sarah Henrickson retweeted
11 Aug 2023
Why do some people have strong immunity after vaccination and others don't? Join our team as a post-doc to study this! tinyurl.com/nyuPostdoc and teamtfh.org for more. Please RT! #immunology #postdoc
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Sarah Henrickson retweeted
2 Jun 2023
In a new @SciImmunology study, our researchers have shown that IgA acts as a “tuner” that regulates the number of microbes the body sees every day. This may explain why some patients with IgA deficiency have symptoms, while others do not. Read more below. ms.spr.ly/6013g5vCv
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Sarah Henrickson retweeted
26 May 2023
In @SciImmunology, @ChildrensPhila researchers provide new model for understanding the most common primary #immunedeficiency in children, Selective IgA deficiency. ms.spr.ly/6013gjhZ1
Image: ©2023 Children's Hospital of Philadelphia. All rights reserved. Illustr. B. Bennett.
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27 May 2023
Thanks John! There’s definitely more to do, from further defining how absent gut IgA dysregulates immune cell activation and cytokine levels to understanding which patients will become symptomatic and how to predict and prevent it. #ImmuneHealth at @CHOP_Research and @UPenn_I3H!
27 May 2023
Really excited to see this wonderful paper from @henricksonlab and @LabSilverman Have seen this story developing over the years - Very interesting. Could IgA levels be a component of overall #ImmuneHealth? Great paper...congrats to the authors dx.doi.org/10.1126/sciimmuno…
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Sarah Henrickson retweeted
26 May 2023
So excited for this story on IgA deficiency to be out at @SciImmunology ! Great collaboration with @henricksonlab. We were curious why most kids with IgA deficiency were not symptomatic. What exactly is IgA doing for the mucosal and systemic immunity? dx.doi.org/10.1126/sciimmuno…
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20 Nov 2022
Time to explore a new place to learn and discuss, so I’m heading to Mastodon. I hope to continue our conversations there!
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13 Nov 2022
Welcome to Penn!
13 Nov 2022
I am excited to announce that I'll be joining the University of Pennsylvania as an Asst. Professor in the Department of Systems Pharmacology and Translational Therapeutics. The #BabdorLab will study the dialogue between the #Microbiome & the #ImmuneSystem for #PrecisionMedicine.
ALT Dr. Joel Babdor, incoming Asst. Professor at home sharing the news.
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8 Nov 2022
VOTE. If you’re driven by one issue or a party. If you’ve voted for decades, if it’s your first time or if it’s been awhile. If you show up because of the town school board or a Senate race affecting the nation. Democracy is just a concept (and it’s in danger) if we don’t VOTE.
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26 Oct 2022
So great to find another group excited about type 2 immunity and CD8 T cell exhaustion! Thanks for visiting our Penn&CHOP community @PennIFI!
26 Oct 2022
Thank you @golnaz_v @canna_lab for the invitation to share our labs research at @Penn_IFI. I had a super fun day catching up with old friends @SunnyShinLab @BrodskyIgor and chatting science with new friends. @EvanWeberPhD @metaBailism @henricksonlab @DHerbertLab @LauraVella17
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16 Oct 2022
Congrats!
15 Oct 2022
Celebrating @ldnotar’s election to the National Academy of Medicine at @theNASciences. #PhotosWithAlbert
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13 Oct 2022
Between fantastic talks tomorrow, join @ConreyPeyton at her fascinating poster delving into the impact of amplified mTOR activation on CD8 T cell function at #ESID2022!
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13 Oct 2022
So proud of post-doc Andrea Mauracher after two great STAT1 focused talks in three hours at #ESID2022! Day 2 of a fantastic meeting is underway—it’s wonderful to see so many friends and colleagues in person.
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Sarah Henrickson retweeted
Congrats to the team esp @AllenInstitute for immunology (Claire, Zach, Pete) and @Penn @henricksonlab @LauraVella17 @EJohnWherry on this multi-omic human T cell dataset w/TEAseq, deep dive into naive T cells across age. Really fun collab, lots of data to mine.
7 Oct 2022
Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults biorxiv.org/cgi/content/shor… #biorxiv_immuno
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11 Aug 2022
Move day! Celebrating 3 years of our lab by moving 70 feet down the hall to a beautiful space where we will continue working as a team to better understand mechanisms of CD8 T cell dysfunction in chronic inflammation & inborn errors of immunity. Definitely more fun with windows!
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Sarah Henrickson retweeted
4 Aug 2022
Congratulations to @Jose_S_Campos (@henricksonlab) & @FSRimmuno (@BurkhardtLab), named 2022 @HHMINEWS #GilliamFellows in recognition & support of their commitment to advancing science through inclusion & diversity!🎉 @IGGPenn @IDEAL_Research @PennInspire bit.ly/3viKa91
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