🚨New pub🚨 on the restless hippocampus and trauma memories. We link dynamic hippocampal-cortical coactivations to daily experiences of intrusive trauma memories in PTSD. A tale of collabs and bridging cog neuro w/ lived-experience reports via EMA 🧵
nature.com/articles/s41380-0…
EMA study of dissociative episodes shows that heart rate does not change in relation to dissociation intensity, counter to "hypoarousal models" of dissociation. sciencedirect.com/science/ar…
New research alert!! Interpersonal trauma exposure is associated with altered neural event segmentation mechanisms. Insights into trauma-related memory deficits and perception! @irosso@e_a_olsonlink.springer.com/article/10…
Hi #ACNP2024, this is my 11th ACNP (!). Come see our posters on Monday to chat neuroimaging and digital phenotyping in PTSD, led by Steve Granger, Kevin Clancy, Nate Harnett. I'll also be helping with discussion @ table 61 of the Women and Gender Minority Luncheon .come join us!
We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣
Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️
This was a fun pub. As part of a larger study, we're using EMA to track trauma memories. Clinicians often ask us whether participants’ symptoms change during the EMA period. Great question, so we took a look! Congrats to first-authors Yara Pollmann and Kevin Clancy. More to come.
🆕in DPN:
Specific symptom change associated with ecological momentary assessments of intrusive trauma memories
@irosso & team @McLeanHospital show that 2 weeks of reporting on unique qualities of trauma memories leads to reductions in intrusion symptoms
nature.com/articles/s44277-0…
NEW lab logo NEW job posting (link below)!
The Biological Embedding of the Environment and Stress (BEES) lab at #DukeUniversity is #hiring a full-time in-person research assistant to conduct human neuroimaging research on traumatic stress.
I am still reeling from how wonderful today has been. MMHRSP worked hard to get these students from underrepresented backgrounds here and give them the best research experience. We advocated for them. We connected & formed community. What a delight to celebrate their growth 🥹
Y'all, I am so proud of this paper! ⬇️ Where we live can influence our likelihood of developing PTSD! But research on resilience after trauma has often focused on individual 🧍 factors and overlooked influential neighborhood 📷factors that may help mitigate the PTSD development
New pub in @BiologicalPsyc1, collaboratively across trauma research labs @McLeanHospital, led by Nate Harnett. We review the relevance of visual processing in PTSD, esp the impact of stress on affective-visual circuitry.
biologicalpsychiatryjournal.…
New research in @dpn_journal unveils potentially distinct patterns of default mode network (DMN) connectivity between posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) following mild acute stress. (🧵1/2)
rdcu.be/dLpKy
ALT Alterations of the Default Mode Network (DMN) connectivity strength are primarily localized in nodes of ventromedial prefrontal cortex (specifically, nodes of the left medial orbitofrontal, and of the right rostral anterior cingulate) and in the left precuneus. https://rdcu.be/dLpKy
Abstract:
✅Ketamine "tablets were effective, safe & well tolerated"
Actual results:
❌At primary endpoint of 13 weeks, 0 of 4 ketamine groups outperformed placebo /re remission
❌At 13 weeks, only 1 of 4 outperformed placebo /re response, with a beautiful p-value of 0.046 🤪
Extended-release ketamine tablets provide a promising alternative for patients with TRD who have not responded to other treatments.
Any thoughts @mehta_mitul72 @EikoFriednature.com/articles/s41591-0…
This is incredibly moving!
Please take 10 minutes to watch this.
Suicide can affect anyone.
Small acts of kindness can save lives.
If you are struggling, help is available:
@samaritans 116 123
Thank-you @Wolves
An incredibly powerful video by @Wolves, well done to them for raising awareness. 👏
Don’t suffer in silence, there is always somebody that will listen. ❤️
Thrilled to share our new publication in @NatMentHealth! We took a longitudinal, dynamic and transdiagnostic approach to define the r factor for post-trauma resilience that explains >50% of variance in mental wellbeing 6-months after #trauma (1/9) – nature.com/articles/s44220-0…