Science writer, @FredHutch News, frmr @seattletimes & @ohiodotcom reporter, @educationlab, @soljourno, Knight Science Journalism Fellowship at MIT @KSJatMIT

Joined September 2013
86 Photos and videos
John Higgins retweeted
🧬 Surprising findings from the Hahn Lab at @fredhutch! Dr. @LMahendrawada’s new study shows yeast transcription factors have far less binding overlap than expected—challenging assumptions in #GeneRegulation. šŸ“° bit.ly/4ipY9Qg šŸ“– @Nature: go.nature.com/42zR1wd
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Honored to work with and write about such smart people šŸ¤“ !
Honored to see our work highlighted by @fredhutch and @HutchBasicSci. In this study, We mapped the binding and regulatory targets of nearly all yeast transcription factors and found that the classic model often doesn’t hold. Check out the paper here nature.com/articles/s41586-0…
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John Higgins retweeted
Honored to see our work highlighted by @fredhutch and @HutchBasicSci. In this study, We mapped the binding and regulatory targets of nearly all yeast transcription factors and found that the classic model often doesn’t hold. Check out the paper here nature.com/articles/s41586-0…
In new work published today in @Nature, researchers in @HutchBasicSci discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate bit.ly/4iu9YoM
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John Higgins retweeted
Interested in doing a postdoc in Seattle? Join us on May 6 for Seattle DROP, a virtual biomedical postdoc recruitment event. The first 250 US registrants enjoy lunch via delivery voucher! 🄪 All postdoc candidates are invited to attend. šŸ‘‡šŸ‘‡šŸ‘‡ Register: tinyurl.com/seattledrop25

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I was there and he was terrific!
Last Saturday, at the park I once (miserably) ran around in 7th grade PE, I stood on a picnic table to stoke the patriotic spirit of 3,000 of my neighbors — and it was a thrill I’ll never forget. I had just flown home the night before from Istanbul, where a grassroots upwelling of concerned citizens is standing up to autocracy, making our local gathering feel even more poignant. I thought you might enjoy a few highlights from the speech I wrote on the plane flying home. Please join me in spirit — and if you have any great photos or reflections from your own local #HandsOff rally, I’d love to see them!
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John Higgins retweeted
Last Saturday, at the park I once (miserably) ran around in 7th grade PE, I stood on a picnic table to stoke the patriotic spirit of 3,000 of my neighbors — and it was a thrill I’ll never forget. I had just flown home the night before from Istanbul, where a grassroots upwelling of concerned citizens is standing up to autocracy, making our local gathering feel even more poignant. I thought you might enjoy a few highlights from the speech I wrote on the plane flying home. Please join me in spirit — and if you have any great photos or reflections from your own local #HandsOff rally, I’d love to see them!
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John Higgins retweeted
We as a scientific community need to be more intentional than ever in supporting, mentoring, and being available to help scientists from disadvantaged backgrounds. I urge everyone to think deeply about what they can do. For example… 🧵
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John Higgins retweeted
10,000 employees of #HHS & its agencies — #CDC, #FDA, #NIH, etc — are losing their jobs. @statnews wants to give the public a closer look at what is being cut & what might be lost as a result. If you're one of these workers, please tell us: statnews.com/2025/03/27/hhs-…
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John Higgins retweeted
US government funding has brought cancer science to the point where new discoveries are accelerating & the stage was set for major gains over the coming decade. But deep & puzzling cuts instigated by the new administration are throwing all that into doubt, @angRchen reports. statnews.com/2025/03/24/trum…
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John Higgins retweeted
🧬 Researchers at @fredhutch have uncovered an overlooked mechanism driving aggressive breast and brain tumors. Learn more about the 64 ancestral genes investigated by the Henikoff lab: bit.ly/3XIke4Y @ScienceMagazine abstract: bit.ly/4iGJAbtResearchers
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"This all began with a phone call,ā€ Henikoff said. ā€œIt’s the kind of thing that’s perfect for Fred Hutch. We are integrated. We know one another. It’s like one family.ā€
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies. bit.ly/43kHcCV
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John Higgins retweeted
Two essential CDC training programs—the Public Health Associate Program (PHAP) and Laboratory Leadership Service (LLS)—are reportedly being dismantled. Our ability to detect and contain health threats including H5N1 is already strained. This not the way to make America healthier. statnews.com/2025/02/18/trum…
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John Higgins retweeted
The shock waves from the Trump administration's assault on the world of science will reverberate for years go come. Progress is being thwarted. Cures are further out of reach. statnews.com/2025/02/14/trum…
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John Higgins retweeted
13 Feb 2025
Out in Science 🧬! Using FFPE-CUTAC to profile RNAPII, we discovered that histone gene hypertranscription predicts rapid cancer recurrence and is linked to chromosome losses in meningioma and breast cancer. One more step to unraveling cancer progression! science.org/doi/10.1126/scie…
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Stay tuned for a more comprehensive Fred Hutch News story about this study and how researchers from our Basic Sciences and Human Biology divisions are leveraging tools and methods developed at the Hutch to make precision oncology more, well, precise.
Researchers at Fred Hutch have discovered an overlooked mechanism driving aggressive breast and brain tumors involving genes so ancient — more than 2 billion years old — that they fly under the radar of standard genetic sequencing methods. 1/9 science.org/doi/10.1126/scie…
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The teaching bond is one of humanity's most enduring and consequential relationships. It connects us with each other and across generations. Seeing its many expressions in science has made my job especially gratifying.
Everything feels weird and uncertain, and I can only imagine how trainees feel right now… so are some things mentors can do to support mentees during these challenging times:
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John Higgins retweeted
29 Jan 2025
🚨 Reminder: Our final #HannaGrayFellows Program informational webinar is tomorrow, January 30, from 3:30–4:30 PM ET! Don’t miss your chance to get answers to your questions directly from the program team. Register now: hhmi.news/40ymhuq šŸ‘ˆ
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