Our new preprint is out: we solved the structures of HIV-1 matrix (MA) from intact virions by SPA. The structure led us to a surprising discovery resolving a long mystery in HIV-1 biology – peptide SP2 regulates the maturation of the HIV-1 matrix. 🧵1/x
tinyurl.com/c7szhtfa
A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses | @VirusesImmunity Science Immunology science.org/doi/10.1126/scii…
🌏 Congratulations to Professor Patrick Reading on his appointment as Director of the WHO Collaborating Centre for Influenza! Prof Reading replaces Prof Kanta Subbarao, Honorary Fellow at @TheDohertyInst who led the Centre for eight years before taking up a prestigious professorial position in Canada earlier this year. @TheRMH @UniMelbMDHS go.unimelb.edu.au/wf98
We are delighted to share that AHRI director for basic & translational science Prof @Thumbi_Ndungu has been elected as a member of @theNAMedicine
Election is one of the highest honours in the fields of health & medicine.
🎉 Congrats, Thumbi!
More ➡️ ahri.org/prof-thumbi-ndungu-…
Wow! Spectacular news for the HIV prevention armamentarium: Lenacapavir showed 100% efficiency...they stopped the blinded phase of the trial to offer it to all participants...aaand it's twice yearly regimen! long way since the muliple horse pills per day!
reuters.com/business/healthc…
What has 126 figure panels and a completely new antiviral pathway? The @GammonLab's latest paper in @NatureMicrobiol, featuring student Emily Rex's tour de force discovery of the FEAR pathway. Huge congrats to the team! nature.com/articles/s41564-0…
Endogenous feline leukemia virus long terminal repeat integration site diversity is highly variable in related and unrelated domestic cats dlvr.it/T2m6hm
Retrovirology is proud to have a new article collection, entitled "HIV infection of uncommon host cells", guest edited by J Victor Garcia-Martinez of University of North Carolina
Read the published articles at:
biomedcentral.com/collection…
BREAKING🔔 A new study from G2P-Japan🇯🇵 is out! The preprint will be out so soon, but we first show our results on the efficacy of XBB.1.5 monovalent vaccine - comparison between infection-naïve and XBB-infected individuals. Please retweet/repost🔥 1/
POLE3 is a repressor of unintegrated HIV-1 DNA required for efficient virus integration and escape from innate immune sensing | Science Advances science.org/doi/10.1126/scia…
Selective control of transposable element expression during T cell exhaustion and anti–PD-1 treatment | Science Immunology science.org/doi/10.1126/scii…