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21 Oct 2025
๐ our new paper is out in Nature.
Huge congrats to everyone for their creativity, persistence and brilliant teamwork! ๐ฅณ๐
It all started many years ago with a failed experiment...
๐ full ๐งต on Bluesky ๐ฆ
Nature research paper: Hijacking a bacterial ABC transporter for genetic code expansion
go.nature.com/3J2iTSE
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5 Oct 2024
๐ฅ We have two open full prof positions at our institute (LOC) at @ETH_DCHAB @ETH_en
1. Synthetic Organic Chemistry
2. (Bio)Analytical Chemistry
Apply until Nov 15 and be our colleague!
ethz.ch/en/the-eth-zurich/woโฆ
3 Oct 2024
Come be our colleague ๐. Two positions (synthetic organic and (bio)analytical) open at our institute (LOC). Amazing students and staff, colleagues, facilities, location, and long-term funding perspectives. What are you waiting for? Apply today ๐. @ETH_DCHAB #chemjobs
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27 Sep 2024
Happy that this is finally online!
Genetic code expansion approaches to decipher the ubiquitin code @ACSChemRev
Many congratulations to Vera, Max and Marco!
@VeraWanka @MaxFottner @MarkoCigler ๐ฅ๐๐ฅณ
pubs.acs.org/doi/10.1021/acsโฆ
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8 Aug 2024
On our way to #GCE2024 in Corvallis @GCEcenter, starting with a small Chinlab reunion in San Francisco. So great to see you all again! Inja, Wolfgang, Tao, Sebastianโฆlike in old times ๐คฉ๐
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10 Jun 2024
Many thanks Daniela @DankovaDaniela and @ChristianAOlsen for writing this comprehensive News and Views!! We really appreciate it ๐!!
10 Jun 2024
I'm happy to share our News & Views article featured in @NatureChemistry, highlighting the excellent work on site-specific incorporation of glutarylated and succinylated lysine residues into multidomain proteins via genetic code expansion by @klanglab!
nature.com/articles/s41557-0โฆ
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26 May 2024
We have a new Dr ๐๐จโ๐in the @klanglab! Many congrats Toni, Dr. Murnauer, we are very proud of you! ๐๐ป๐ and many thanks to co-examinator @StephanHacker2 who came all the way from Leiden and to @mvkovalenko for chairing the committee! ๐จโ๐ฌโ๏ธ๐ #tetrazines #DMBO #bioorthogonal
25 May 2024
It was great to be at @ETH Zurich for the PhD defense of Anton Murnauer of the @klanglab. He performed a lot of exciting science on genetic code expansion and bioorthogonal chemistry. Congratulations, Dr. Murnauer, and thank you, @klanglab, for inviting me doi.org/10.1002/anie.2019082โฆ
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25 Apr 2024
Very excited to co-organize GCE2024 with @AChemSynBio and @Mehl_lab at @GCEcenter!
Come to Corvallis, Oregon to hear about the newest in genetic code expansion! We have a stellar speaker lineup from academia and industry!๐
Retweet and register!
gceconferences.org/
25 Apr 2024
๐จ๐จAll genetic code expansion enthusiasts, donโt miss the GCE 2024 conference this summer (gceconferences.org/)! Fantastic speakers both from academia and industry. Please retweet! @klanglab @Mehl_lab
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29 Mar 2024
Genetically encoding negatively charged lysine PTMs succinylation/glutarylation and studying their funcional roles! Great team effort by first authors @ML_Jokisch and @Maria_Weyh! Congrats @Maria_Weyh @ML_Jokisch @MaxFottner and Anh! ๐ฅณ๐คฉ๐๐จโ๐ฌ๐งโ๐ฌ @klanglab
nature.com/articles/s41557-0โฆ
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29 Mar 2024
SucK and GluK can be encoded co-translationally as temporarily masked thioester derivatives. They regulate enzymatic activity of metabolic enzymes (GAPDH), protein-protein interactions (Ub signaling) and DNA-protein intereactions (DNA clamp loading)
#PTMs, #GCE @NatureChemistry
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25 Mar 2024
Straight to the face ๐
Nice collaboration with @houk1000 and @Click_Chemist! Small cycloalkane fusions enhance the cycloaddition reactivity of dibenzocyclooctynes (especially towards tetrazines ๐ฉท)
Many congrats to Toni and Dennis! ๐งช๐ป๐งโ๐ฌ๐งโ๐ป
#bioorthogonal
doi.org/10.1039/D3SC05789E
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29 Feb 2024
Very much looking forward to this!! ๐คฉ Exciting chembio in great company in one of my favourite european cities (with some of the best restaurants ๐), what is not to like! Many thanks for inviting and organizing @LabPless @stromgaardlab @ChristianAOlsen and everyone involved.
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29 Jan 2024
Small molecule ubiquitylation ๐
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25 Jan 2024
This is pretty cool! ๐คฉ๐
25 Jan 2024
Another exciting new tool to engineer biology from the Jason Chin Lab >>> Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli | Science science.org/doi/10.1126/scieโฆ
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6 Nov 2023
Looking forward to this one!
6 Nov 2023
Application deadline extended to Nov. 12!
Discuss the development of chemistry-based tools to unravel signaling networks in cells tissues #chembio
Registration hotel meals covered
Learn more apply @ bit.ly/CHM2024
@HHMINEWS @BiochemSoc @nchembio @HHMIJanelia
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Kathrin Lang retweeted
30 Oct 2023
๐ฉโ๐ฌ๐จโ๐ฌ Calling all Prof. & Independent Senior Scientists in ๐จ๐ญ chemical biology! ๐งช๐ฌ Join ๐จ๐ญSNE chembio community sne-chembio.ch& become a member:
๐ bit.ly/492pAw5 sne-chembio.ch
๐exclusive benefits ๐
๐ share the info!
#ChemBio #Together
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13 Oct 2023
very much looking forward to having you here, Michael!
safe travels!
13 Oct 2023
Really excited to be visiting ETH Zรผrich @ETH_DCHAB next Monday to meet new people and give a talk on our latest work on controllable nucleic acids ๐๐คฉ๐งฌ
Thanks to @klanglab for the invite!
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18 Sep 2023
We have a new doctor in the @klanglab! Well done to Kristina - Dr. Krauskopf - who successfully defended her thesis!๐๐ฅณ๐ Many thanks to @SieberLab and Hubert Gasteiger for being on the committee at TUM! Very sorry for only being present via Zoom and missing the party fun ๐ค๐ฆ ๐
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18 Sep 2023
Oh yes!! Waiting and rooting for this for years! DNA synthesis/Marvin Caruthers...there would be no molecular biology without! Maybe 2023 is the year! ๐ช #chemnobel
18 Sep 2023
It's #chemnobel season, so your reminder that DNA synthesis/Marvin Caruthers needs to win!
Without DNA synthesis there is NO *PCR*, *sequencing*, *cloning*, *CRISPR*, *siRNA*, *synthetic biology*, *mRNA vaccines*, *nucleic acid therapeutics*, *Nanotech*
What more am I missing?
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5 Sep 2023
Really enjoying my walks to and from work in this gorgeous september weather @ETH_DCHAB โ๏ธ๐๏ธ๐ฎ๐๐๐จ๐ญ
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