Sir Henry Dale Fellow, King's College London. Interested in proteins and their post-translational modifications.

Joined September 2019
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We chemically synthesized old histones containing an isoAspartate residue to measure the impact of aging on chromatin integrity. We found that chromatin is surprisingly tolerant of this particular form of wear-and-tear, although local perturbations were observed.
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Congratulations co-1st authors @_TianzeZhang & Luis Guerra @kclchemistry and great collaboration with Iana @Beatfierz and Jon.
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ManuelMuellerLab retweeted
I have an AstraZeneca-funded PhD position available (4 years), based in my lab (School of Chemistry, University of Nottingham); start date Oct 2025! Traceless Chemoenzymatic Peptide Synthesis Application deadline: 6 Jan 2025. Get in touch!!! findaphd.com/phds/project/tr…
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ManuelMuellerLab retweeted
Come and join my group @TheCrick - we have a PhD tinyurl.com/rhtfbdx4 in metal-peptidic cages and high affinity binders, and will advertise a 3 year PDRA in December for a Chemical Biologist with synthetic and cell work experience. Email if interested, retweets appreciated!
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Thrilled to highlight our work on chemoenzymatic protein modification, recently published in @J_A_C_S : Kinetic Resolution of Epimeric Proteins Enables Stereoselective Chemical Mutagenesis | Journal of the American Chemical Society (acs.org)

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Great collaboration with @rli22 and @nott_lab
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Replying to @J_A_C_S
Led by PhD student Guljannat, we introduced a kinetic resolution step to dehydroalanine chemistry. By cleaving the D-amino acid-containing isomer with a D-peptidase, we combine the stereoselectivity of enzymes with the broad scope of chemo-selective Dha functionalisation.
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ManuelMuellerLab retweeted
A new scholarship is available to next year's MRes Chemistry students - apply by 31 August. The Mackenzie Family Scholarship established in the memory of Mr F.H. Mackenzie is a prestigious award covering a £22,000 stipend ⚗️ Find out more 🔗⬇️ loom.ly/72FInaE

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ManuelMuellerLab retweeted
Excited about engineering powerful biocatalysts? Check out the open PhD position in my group! 👉zhaw.ch/en/jobs/vacant-posit… Please spread the word!🇨🇭🏔️🧪🌿☀️ @NCCR_Catalysis @ZHAW Photo: ZHAW Wädenswil / Frank Brüderli
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ManuelMuellerLab retweeted
Late breaking PhD project to work with me and Charlie on mass spec crosslinking in heart disease! To start by Jan 2025. UK fees only, apply by 9th August.
Fully-funded EPSRC PhD opportunity @UoL_LICAMM @AstburyCentre developing live-cell chemical cross linking methods to study myosin folding and disease with myself and @MWrightLab phd.leeds.ac.uk/project/1985… apply by 9th August
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ManuelMuellerLab retweeted
14 Jun 2024
🌟 Join Our Team! 🌟 We're seeking a talented #postdoc to join us @kclchemistry! Come and explore membraneless organelles, molecular conformations, and enzyme activity with us. 3-year post. Deadline extended to June 30. kcl.ac.uk/jobs/089765-postdo…

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ManuelMuellerLab retweeted
29 Feb 2024
We are hiring! We look for Postdocs in the field of biophysics / chemical biology of gene regulation within a context of a SNSF Advanced Grant starting in 2024! More details here: epfl.ch/schools/sb/research/…

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ManuelMuellerLab retweeted
21 Feb 2024
Make sure to get your applications in by 3rd of March if you are interested in joining us through this fully funded studentship opportunity with @KawamuraGroup @SciencesNCL @ChemistryNCL @DurhamChemistry
📣 Applications now open for a funded #PhD #chemicalbiology #cyclicpeptides. Exciting opportunity for doctoral research with the Kawamura Research Group and @MosmedC at Newcastle Uni @ChemistryNCL, in collaboration with @novonordisk. More information: ncl.ac.uk/postgraduate/fees-…
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ManuelMuellerLab retweeted
4-year studentship available in my lab at @kclchemistry working at the interface of fundamental synthetic biology and therapeutic biotechnology development - come & join me in the XNA world! Please RT findaphd.com/phds/project/ch…
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