prof at UC Santa Barbara. slslab.org Neuroscience, neuroengineering, and computation. Optics, imaging, circuitry. Sharing notes at labrigger.com
Joined July 2011
- Tweets 3,258
- Following 3
- Followers 3,832
- Likes 3,854
395 Photos and videos
19 Jun 2025
NEW PREPRINT: For 2-photon imaging (or any laser scanning), fast scanning often shrinks the field-of-view and/or decreases resolution.
Che-Hang Yu found a bunch of ways to increase the field-of-view, with no trade-offs in speed or resolution. 1/2
biorxiv.org/content/10.1101/…
2
2
14
1,052
19 Jun 2025
It seems like magic!
Also works for increasing the phase range of adaptive optics!
Check out this video if you want to be walked through the preprint. youtube.com/watch?v=qO1nenu6…
2/2
4
761
Spencer LaVere Smith retweeted
19 Jun 2025
Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer Smith's lab @Labrigger. Neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from @pacificoptica . I'd love to build this for a client at some point! biorxiv.org/content/10.1101/…
2
6
23
1,806
Spencer LaVere Smith retweeted
19 Jun 2025
Beautifull! Nisam Cousa (>3 mm x > 3mm) by Che-Hang Yu et al.
2
11
900
17 Jun 2025
This is actually fun. Try it!
Your preprint -> AI-generated fake podcast -> video with actual human commentary -- It's remarkably effective!
Awesome optics work to unlock big-and-fast in vivo two-photon calcium imaging, by Che-Hang Yu.
youtube.com/watch?v=qO1nenu6…
2
12
982
Spencer LaVere Smith retweeted
23 Mar 2025
FYI -- I mostly post here: neuromatch.social/@sls
1
4
1,054
2 Feb 2025
I wrote to my representatives again. Maybe at this point I should just let them subscribe to my newsletter.
4
895
Spencer LaVere Smith retweeted
26 Jan 2025
Announcing for the first time: the largest, fastest scanning multiphoton imaging pacificoptica.com/ventana/ #photonicswest #spie
4
18
1,429
Spencer LaVere Smith retweeted
26 Jan 2025
Huge field of view with a scan engine pacificoptica.com/ventana/
1
21
1,254
Spencer LaVere Smith retweeted
22 Dec 2024
The Ventana SL and Ventana TL are now available. pacificoptica.com/ventana/ This is a new standard in scan engine optics. Nothing else comes close. These optics enable diffraction-limited imaging over a huge field-of-view. They're easy to integrate into your systems.
2
5
1,133
17 Nov 2024
I have new posts and whatnot here:
neuromatch.social/@sls
I'm on mastodon because it's simple, clean, open, and a community. It's not perfect, but there's no profit-driven algorithm.
Bluesky is nice from what I hear, but it could easily run into the same issues. (1/3)
1
2
669
17 Nov 2024
I'm on social media to share with technical communities in neuro, optics, computation, ML, etc. I don't need a free-for-all platform with the potential to reach millions.
Mastodon is a good fit for me. (2/3)
1
2
550
17 Nov 2024
If you want another level, try our slack-like Nemonic group. Contact me if you want access.
2p.ece.ucsb.edu/
and/or try this link: 2p.ece.ucsb.edu/signup_user_…
3
539
29 Oct 2024
I'm excited about this. If your experiments benefit from having a large field-of-view scanned fast at high resolution, this is beyond anything else out there. It's ready to go. If you want in early, email me and we'll let you know the details. No pressure. It's just very cool.
28 Oct 2024
Here are a couple of shots of one of our new products. Unlocking the widest fast scanning ever. Looking forward to sharing more about this new tech! pacificoptica.com See more. Measure more.
1
22
2,110
21 Oct 2024
Called it.
21 Oct 2024
2¹³⁶²⁷⁹⁸⁴¹−1, discovered today, is the largest known prime. It's a Mersenne prime (2ᵖ-1), which are easier to find.
It took nearly 6 years for the GIMPS software to find it after the previous largest known prime. It was also the first Mersenne prime found using GPUs.
4
1,138
Spencer LaVere Smith retweeted
We grieve the passing of Dr. Yves Frégnac.
Yves has shaped the study of cortical processing and plasticity. He heralded interdisciplinarity and was one of the founding fathers of our institute.
Our thoughts go to his family and to his friends in the community and beyond. x.com/NeuroPSI_saclay/status…
4
37
94
36,605
Spencer LaVere Smith retweeted
19 Oct 2024
The Diesel2p: The do-anything 2p for neuroscientists. Huge field-of-view, dual scan engines, fast, easy-to-use, and already proven in neuro labs around the world. pacificoptica.com/diesel2p/
1
14
1,010
Spencer LaVere Smith retweeted
16 Oct 2024
Imagine a world where blindness or low vision is no longer a barrier. 🌍👁️ With support from NLM & NIH, @UCSB researchers are developing a "Smart #BionicEye" that uses #AI to create practical artificial vision. Learn more about this tech in #NLMMusings: loom.ly/SHyQhLw.
1
3
11
1,229