Dir, Computational Health Informatics Program @Bos_CHIP | Harvard Med Prof & MD | Nat Acad Med Leadership Council & Co-Chair Digital Health Action Collab #AI

Joined December 2008
311 Photos and videos
Pinned Tweet
9 Mar 2020
It took a village. New HHS rule ensures an app written once will run anywhere in the healthcare system. & patients can access a computable copy of their medical record. This journey began > a decade ago when @zakkohane and I proposed a health care API in the @NEJM @SMARTHealthIT
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Ken Mandl retweeted
4 Mar 2025
Perspective by Kenneth D. Mandl, MD, MPH (@mandl): Unseen Commercial Forces Could Undermine Artificial Intelligence Decision Support nejm.ai/4hyjmYB #AIinMedicine
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6 Feb 2025
My Perspective in @NEJM_AI. AI could distort clinical decision-making in ways that prioritize profit over patient care. Oversight & regulation must go beyond performance metrics alone to address hidden commercial forces that could shape decision support. ai.nejm.org/doi/full/10.1056…
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8 Jan 2025
If #AI is General Purpose Technology (the other GPT 🙂), akin to steam power, electricity and information technology, it’s poised to reshape the workforce in profound ways @LHSummers @nberpubs nber.org/system/files/workin…

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6 Jan 2025
One week left to apply
18 Dec 2024
🚨 Faculty Opportunity at Harvard Medical School 🚨 @Bos_CHIP at Boston Children’s Hospital is hiring research faculty to advance AI & computational approaches in healthcare. 🗓️ Apply by Jan 13, 2025 🌐 chip.org/employment/instruct…
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19 Dec 2024
House Taskforce on AI: "If AI tools cannot easily connect with all relevant medical systems, their adoption and use could be impeded." But is well-addressed by @HHS_TechPolicy 21st Century Cures Act rule, as I have described in @NatureMedicine with @gotdan and @JoshCMandel
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19 Dec 2024
"Integration of AI in healthcare requires an interoperable digital data ecosystem" bit.ly/3P5kVk8

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19 Dec 2024
🚨 No Embargo (was 12 months) This is a big deal change to NIH’s Public Access Policy. Starting 12/31/2025, all NIH-funded research must be freely available on PubMed Central upon publication. Enhancing transparency & public access to taxpayer-funded research. 🌐📚 #OpenAccess
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18 Dec 2024
🚨 Faculty Opportunity at Harvard Medical School 🚨 @Bos_CHIP at Boston Children’s Hospital is hiring research faculty to advance AI & computational approaches in healthcare. 🗓️ Apply by Jan 13, 2025 🌐 chip.org/employment/instruct…

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17 Dec 2024
🔬 Harvard Medical School Postdoc in AI & Computational Health Join CHIP at Boston Children’s Hospital to advance healthcare with multimodal real-world data 🌟 Help shape the future of medicine. Apply now: chip.org/training/nih-funded…

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Ken Mandl retweeted
Here's how today's HTI-2 Final Rule stacks up against @SMARTHealthIT comments (thanks Gemini Experimental!) --- Here's a breakdown, organized by the topics you raised in your comments: 1. FHIR Bulk Data Enhancements Export Performance Parity: Status: NOT ADDRESSED in this final rule. This was one of the more ambitious proposals, and it seems ASTP/ONC has decided to defer it for later consideration. This topic falls under the broader category of proposals from HTI-2 that were not addressed in this particular rule. Assessment: Feedback not heeded in this final rule; likely deferred. Server Support for Patient Group Creation: Status: NOT ADDRESSED in this final rule. Similar to export performance parity, this was likely deferred. ASTP/ONC has acknowledged the early work in the Argonaut Project but has not yet taken action to incorporate it into the regulations. Assessment: Feedback not heeded in this final rule; likely deferred. Server Support for _since and _type: Status: NOT ADDRESSED in this final rule. This proposal, while valuable, was likely deemed less urgent than other priorities addressed in this partial final rule. Assessment: Feedback not heeded in this final rule; likely deferred. 2. EHI Export Status: NOT ADDRESSED in this final rule. Your recommendations for enhancing EHI Export, including download functionality in patient portals, third-party app access, and handling of non-computable formats, were not part of this partial final rule. These are significant proposals that likely require more consideration and potentially a separate rulemaking process. Assessment: Feedback not heeded in this final rule; likely deferred. 3. Image Links in API Responses Status: NOT ADDRESSED in this final rule. The specifics of image access via API were not covered in this partial final rule. Your concerns about the shareability and programmatic accessibility of "imaging links" remain unaddressed for now. Assessment: Feedback not heeded in this final rule; likely deferred. 4. Subscriptions for US Core Data Status: NOT ADDRESSED in this final rule. The proposal to require subscription capabilities for US Core data was not included in this partial final rule. Your recommendations regarding a phased approach, alignment with Argonaut's work, and specific technical details were not acted upon at this time. Assessment: Feedback not heeded in this final rule; likely deferred. 5. Dynamic Registration outside of Trust Frameworks Status: NOT ADDRESSED in this final rule. The proposal to adopt dynamic registration, along with your recommendation to support self-signed certificates, was deferred. Assessment: Feedback not heeded in this final rule; likely deferred. 6. CDS Hooks Status: NOT ADDRESSED in this final rule. The inclusion of CDS Hooks 2.0 in the certification requirements was not part of this partial final rule. Assessment: Feedback not heeded in this final rule; likely deferred. Overall Assessment This final rule primarily focused on establishing the regulatory framework for TEFCA and making some limited updates to the ONC Health IT Certification Program. It did not address the majority of the substantive proposals in your comments, which were largely related to: Enhancements to FHIR Bulk Data Access Improvements to EHI Export Specific API requirements for image access Implementation of subscriptions for US Core data Details of dynamic registration Adoption of CDS Hooks It's important to reiterate that the absence of these topics in this final rule does not necessarily mean they have been rejected. ASTP/ONC has explicitly stated that the remaining proposals from HTI-2 are still under consideration for future rulemaking. It's likely that your comments will be taken into account as they develop those future rules. It may be worthwhile to follow up with ASTP/ONC during future comment periods or through other engagement channels to reiterate your recommendations and track their progress.
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6 Mar 2024
Come join us tomorrow, Thursday at 4pm to hear the wonderful @chrissyfarr
Excited to join my friend @mandl to chat with the amazing crew at Boston Children's about *all the things.* I'm an open book as you all know. If you want to join us, Zoom link here: bostonchildrens.zoom.us/webi…
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Ken Mandl retweeted
Excited to join my friend @mandl to chat with the amazing crew at Boston Children's about *all the things.* I'm an open book as you all know. If you want to join us, Zoom link here: bostonchildrens.zoom.us/webi…
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Ken Mandl retweeted
EHI Export insight: over 100 individual users (i.e., provider org staff) contributed to some aspect of my EHI in the past 6 years of ambulatory care. This diagram shows only users & tasks mentioned at least 10 times. (Task labels generated by GPT-4, based on Epic's EHI schema.)
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Ken Mandl retweeted
1 Feb 2024
Join us @bos_chip on Monday for a conversation with one of healthcares most storied CEOs. Register here bostonchildrens.zoom.us/webi….
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Ken Mandl retweeted
A message from Quinn Sutherland aka ⁦@ReelQuinn, who is a treasure⁩: “Hi everyone. Due to some setbacks in my health I’ve been struggling to make ends meet. If you can help out in any way, I’d appreciate it. Thank you!” gofundme.com/f/everything-ge…
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Ken Mandl retweeted
3 Feb 2024
Chapter11andMe
within months you will be able to buy genomics data from 14 million americans for /- $200m? the inevitable fire sale of this mess to an overseas PE firm is going to be a national security matter on the scale of which we haven't seen in healthcare in years
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