Christian, mathematician, reader, 🇺🇸. Assistant Prof at @MoffittNews: #MathOnco, cancer evolution, antifragility, cellular automata, #sciart
Joined March 2009
- Tweets 9,366
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Jun 9
This is a really neat paper. Some intriguing results on the relationship between clonal expansion and survival outcomes. Modeling evolutionary dynamics with treatment induced bottlenecks in clonal hematopoiesis
‼️📢Now available online ‼️
Evolution of clonal hematopoiesis during cancer treatment and its impact on outcomes jci.org/articles/view/204429
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Jun 12
This year, we're exerting more effort to communicate with non-field experts in the #mathonco newsletter, starting with short 200-word editorial pieces on a range of topics.
Can you please drop me or @fpradelli94 a message:
1) if you're a non-scientist subscriber and
2) with your ideas for topics to cover?
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Jeffrey West retweeted
Jun 11
Nikita Kucherov has won the 2026 Hart Trophy
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Jeffrey West retweeted
‼️📢Now available online ‼️
Evolution of clonal hematopoiesis during cancer treatment and its impact on outcomes jci.org/articles/view/204429
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Jun 10
I also like the old-timey openings, too. 1951.
Jun 9
What's the best opening sentence of a paper you've ever read?
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Jeffrey West retweeted
This one is fantastic too:
"Sometimes you just kinda phone it in for a year, you know?"
The YOLO v3 paper is a complete banger imo
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Jun 9
What's the best opening sentence of a paper you've ever read?
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Jun 8
“The only meaningful definition of a ‘generalist’ is a specialist who can relate his own small area to the universe of knowledge.”
-P Drucker
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Jun 5
It’s clear that academics often jump too quickly to “the next big thing” but it’s also clear that AI is the exception that proves the rule. It’s time to jump.
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Jun 5
Very interesting pod on AI and implications for studying consciousness with NYU prof David Chalmers
podcasts.apple.com/us/podcas…
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Jun 5
FWIW my personal conviction is that it’s completely ridiculous that chatbots are (or could be) conscious, but I can suspend disbelief long enough to enjoy the podcast.
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Jeffrey West retweeted
Awesome new publication regarding antifragility in pharmacology, very closely related to my own research but on the oncology side of things! Congrats @mathoncbro et al! Very exciting to see all the applications of convexity here :) aacrjournals.org/cancerres/a…
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May 26
Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
aacrjournals.org/cancerres/a…
First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al
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Jeffrey West retweeted
May 29
Interested in Entropy & Aging?
Note that there will be an Entropy in Aging conference and workshop in Cologne end of August, enabled by the International Aging Entropy Open Research Network!
Attendance is free of charge and focused on intimate discussions!
sites.google.com/view/entrop…
@Meyer_DH
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Jeffrey West retweeted
Caldas' Lab paper out together with @ASTRAZENECAUK in CRM:"Real-time cell viability monitoring for high-throughput drug screening using tumor xenograft-derived cells" @CellRepMethods
cell.com/cell-reports-method…
We screened 67 compounds × 43 breast cancer PDTCs (1,117 drug–model combos) but the first story we want to share here is how we measured response.
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May 27
ICYMI—the December 15 issue received the most votes in our cover contest! Congrats to the authors of "Mathematical Oncology: How Modeling Is Transforming Clinical Decision-Making." brnw.ch/21x2S6Q
@ara_anderson @mathoncbro @sandhya212 @MoffittNews #MathOnco
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May 26
Our "evolutionary antifragile therapy" paper is now posted online (Cancer Research):
aacrjournals.org/cancerres/a…
First experimental validation of antifragility in cancer (ALK inhibitors in lung)! An awesome collaboration involving @ara_anderson, @AndriyMarusyk, @Binadesai14 et al
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May 26
@nntaleb, your ideas at work in experimental settings. Next up, clinical translation...
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May 26
Switching between continuous and varied dosing (intermittent) represents the best of both worlds: kill tumor, avoid resistance.
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May 26
We think of antifragile therapy as a class of "evolutionary therapy" and that it represents a path forward for designing adaptive dosing protocols in the future.
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