Takeaways:
- Patients may present on relapse with symptoms not present at baseline. This was observed in approximately 1 in 5 patients in our study. Thus, awareness of the full spectrum of clinical presentation is necessary for both patients and physicians.
- The strongest concordance was observed when evaluating the presence of symptoms at first relapse and likelihood of symptoms also being present at second relapse.
- In our study, absence of cranial symptoms at baseline was associated with no visual symptoms at first or second relapse. 6/7