Associate Professor, Biochemistry and Biophysics, @urochestermed. RNA-targeting CRISPR / RNA acetylation. An Aussie in 'the land of the free'. Music Nerd.
Joined December 2015
- Tweets 646
- Following 1,404
- Followers 1,328
- Likes 6,182
36 Photos and videos
Pinned Tweet
27 Apr 2023
1/n After an arduous but constructive peer review process, we’re excited to share the published version of this work. Lots of added goodies: science.org/doi/10.1126/scie…
3 Nov 2021
1/8: Super excited to share our latest pre-print from the lab, where in close collaboration with @kellogg_liz lab we show that through some pore behavior, the CRISPR-Cas13-activated membrane protein CRISPR-Csx28 pulls the plug on bacteriophage infection. biorxiv.org/content/10.1101/…
22
23
101
50,648
Mitchell O'Connell retweeted
New post-doctoral research position available in my Phage-host interactions (Phi) laboratory at the @otago in the Department of Microbiology and Immunology. The project is focused on defences against jumbo phages. Please share and if interested apply using the link below.
3
30
67
6,456
27 Mar 2025
Woo hoo @Wagnerlab_RNA! Awesome news and well deserved!
27 Mar 2025
Congratulations to RNA biologist Eric Wagner for achieving the rank of #AAASFellow by @AAAS!
Thank you for your extraordinary contributions to science and mentoring the next generation of biomedical researchers.
Read more about Dr. Wagner’s work: urmc.rochester.edu/news/stor…
6
406
16 Sep 2024
My department is hiring! We’re looking for faculty in the department of Biochemistry and Biophysics at the University of Rochester. As I can attest, Rochester provides a highly supportive and collaborative environment and is a great place to work/live: jobs.sciencecareers.org/job/…
2
6
15
2,386
16 Sep 2024
Folks with broad interests in any area of biochemistry and biophysics, including structural and computational biology as well as metabolomics and genomics should consider applying. We will consider all applications on their merit!
1
296
Mitchell O'Connell retweeted
17 Jul 2024
Excited about phage functional genomics, phage engineering, & microbiome editing? The Cress Lab @UCBerkeley @igisci is hiring postdocs in these areas! Come chat w/ me @VoM_2024 & don't miss my presentation w/ @ben_a_adler in the SynBio session Fri @ 11:20am. Retweets appreciated!
22
46
8,239
Mitchell O'Connell retweeted
7 Jul 2024
Keep watch… plenty starting to happen with the #CRISPR conference in NZ next February.
7 Jul 2024
Get ready for #CRISPR2025 in #NewZealand. We are fortunate to have Malcolm White @mfwhite2 as our Keynote speaker.
11
45
4,673
23 May 2024
Big congratulations to @ammolinavargas graduating with his PhD, not to mention all the accolades along the way including the Leadership Award for Excellence in Equity and Inclusion bestowed at graduation. We're all very proud of all your accomplishments and we're gonna miss you!
17
1,394
Mitchell O'Connell retweeted
18 Jan 2024
Join us in April in Boston for the 2024 symposium on the immune system of bacteria ! 🧫🧬🥳
Registration now open: kranzuschlab.med.harvard.edu…
Abstract deadline March 4th.
1
12
54
7,435
8 Dec 2023
The first FDA approval for CRISPR! A historic milestone! Thanks @URochester_SMD for getting a chance on riff on about this special occasion (unrehearsed and unscripted as you might be able to tell!). #URochesterResearch
8 Dec 2023
.@mitchellrayoco1, asst prof of Biochem and Biophysics, who trained w/ Nobel Prize winner Jennifer Doudna, one of the inventors of the revolutionary gene-editing technology CRISPR, weighs in on today's approval for using CRISPR to treat sickle cell patients. #URochesterResearch
9
46
6,370
Mitchell O'Connell retweeted
5 Dec 2023
Now @NAR_Open our two back-to-back papers with @mitchellrayoco1 lab! Our #chemcomp paper unravels the #RNA-mediated allosteric regulation in #CRISPR-Cas13a and discloses functional mutations.
academic.oup.com/nar/advance…
@sou_svk @pablitoarantes @ammolinavargas & Amun Patel
3
15
98
8,224
5 Dec 2023
Now @NAR_Open our two back-to-back papers with @palermo_lab lab! 1) We show that MD-directed point mutations select against #offtargets in #Cas13a, paving the way for new SNP-detecting #RNA-diagnostics. academic.oup.com/nar/article…
@ammolinavargas @sou_svk @pablitoarantes Amun Patel
1
14
57
9,332
5 Dec 2023
And 2) Back-to-back, with @palermo_lab our #chemcomp paper unravels the #RNA-mediated allosteric regulation in #CRISPR-Cas13a and discloses functional mutations.
academic.oup.com/nar/advance…
9
683
28 Oct 2023
Love this! Eric has been instrumental helping me stay afloat starting a lab at Rochester. Sitting down almost high school English teacher style going line by line, pen and paper through a grant application has been transformative about how i think to communicate. A true gift!
28 Oct 2023
We are delighted to announce our next RNA Society Member Spotlight!
rnasociety.org/dr--eric-phiz…
Dr. Eric Phizicky has been a Professor in the Department of Biochemistry and Biophysics at the University of Rochester School of Medicine and Dentistry in the USA for over 35 years. In this month’s RNA spotlight, written by Dr. Isha Verma, Dr. Phizicky talks about his research, shares his advice to trainees, and also recounts his role as the Senior Editor of the RNA Society’s flagship journal.
13
2,289
Mitchell O'Connell retweeted
10 Oct 2023
The Bio Dept at University of Rochester is hiring a TT Assistant Professor in evolutionary genetics/genomics. Review begins 11/1. Come be our colleague! rochester.edu/faculty-recrui…
68
73
22,256
8 Sep 2023
Congrats to @ammolinavargas on hitting his thesis defense out of the park yesterday. Very proud PI. We will miss you but excited for what is next!
2
20
2,855
8 Sep 2023
My department is hiring! We’re looking for faculty in the department of Biochemistry and Biophysics at the University of Rochester. As I can attest, Rochester provides a highly supportive and collaborative environment and is a great place to work/live: jobs.sciencecareers.org/job/…
1
13
25
10,606
8 Sep 2023
Folks with interests in any area of biochemistry and biophysics, especially in signaling pathways and membrane proteins, and those using structural or computational methods please apply! Please reach out if you are interested in learning more about this awesome opportunity!
1
2
586
5 Sep 2023
Excited for this! @ammolinavargas has built an impressive body of work that we're all really proud of!
3 Sep 2023
I am thrilled to announce that I will be defending my doctoral dissertation on Sept 7th 12 PM EST. I invite you to support me on this important occasion and learn more about #CRISPR #Cas13. If you are unable to attend in person, please reach out to me directly for the Zoom link.
10
1,185
Mitchell O'Connell retweeted
7 Aug 2023
Cheers to RNA biologist Lynne Maquat for officially receiving the Gruber Genetics Prize @Genetics2023 in Australia for her work on nonsense-mediated mRNA decay. Proud to have you represent @UofR on an international stage! #URochesterResearch @MaquatLab urmc.info/15L
1
11
46
3,421
Mitchell O'Connell retweeted
5 Aug 2023
Really great collaboration with @mitchellrayoco1 and his student @ammolinavargas , resulting in the development of new and more specific #crispr Cas13a systems !!
4 Aug 2023
1/n Super excited to share our latest pre-print from the lab, where we reveal important considerations when designing Cas13a-based SNP-detection assays to ensure specificity and anticipate designs caveats. 🧵 biorxiv.org/content/10.1101/…
1
7
2,129