Innovative UK MND clinical trial from Euan MacDonald Centre for MND research at @EdinburghUni. Designed alongside people with MND. Searching for new treatments.

Joined February 2021
48 Photos and videos
MND-SMART Amantadine Stage 2 Interim Analysis Results: Amantadine doesn’t slow MND - now we know, and now we move forward. Read more: edin.ac/4cnN3fp #ALS #MND #trial
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We’re very proud to be working closely with the Motor Neurone Disease Association to increase equity of access and opportunities for people living with #mnd #als to participate in clinical #trials
We're proud to announce that we have trebled our investment in the unique MND-SMART trial platform which is driving faster research into potential treatments for motor neurone disease. Read more. 🔗mndassociation.org/media/lat…
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12 Dec 2025
⭐️The winter edition of our biannual newsletter is out now!⭐️ Take a look 👉edin.ac/48QllUW Subscribe on our website to receive the next newsletter directly by email: edin.ac/44K2zxB

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3 Nov 2025
We’re delighted to share that MND SMART is now open for recruitment at Imperial College Healthcare NHS Trust. A very warm welcome to the Imperial team! Read more 👉 edin.ac/47zZLn5 Register your interest to participate in MND SMART👉 edin.ac/490fmPk #ALS #MND
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13 Oct 2025
We’re delighted to announce that MND-SMART is now open for recruitment at Hull Royal Infirmary, offering opportunities for participation to people living with motor neuron disease across the Hull and Humber Region. 🔗 mnd-smart.org/news/mnd-smart…
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MND-SMART retweeted
Wonderful for @mndsmart at @EuansCentre @UKDRI to be profiled in @Forbes Magazine as an exemplar of an innovative patient centred platform trial for #mnd #als following the recent excellent #iDR25 international drug repurposing conference eur02.safelinks.protection.o…
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25 Jul 2025
⭐️The brilliant and dedicated research team at the Southampton General Hospital Trial Centre have now randomised >50 participants to MND-SMART!⭐️ Read more 👉 mnd-smart.org/news/jul-2025-… #MND #ALS #clinicaltrial

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MND-SMART retweeted
We're excited to welcome a new Group Leader to the UK DRI! 🥳🙌 Prof @suvankarpal joins our Edinburgh Centre, where he aims to deliver a streamlined approach to take mechanistic understanding of neurodegeneration into evidence-based clinical trials👉buff.ly/WOVDlGI
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20 Jun 2025
Tacrolimus added as the fourth investigational arm in MND-SMART. MND-SMART uses an innovative #MAMS design to evaluate several potential treatments simultaneously, speeding up the time to identify effective therapies. Read more 👉 edin.ac/4jWf0uM #GlobalMNDAwarenessDay
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18 Jun 2025
🔔 New Trial Centre Open 🔔 Led by Principal Investigator Dr Malcolm Proudfoot, York & Scarborough Teaching Hospitals have joined the MND-SMART team. Read more here 👉mnd-smart.org/news/mnd-smart… #MND #ALS #MNDSMART #MAMS
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MND-SMART retweeted
Uplifting afternoon at the College of Medicine & Veterinary Medicine, University of Edinburgh Staff Recognition Awards. Very proud the @mndsmart team were awarded the Collaboration & Partnership Award. Fortunate to work alongside inspiring colleagues & people with #MND #ALS🙏🏾🥇
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1 Apr 2025
Congratulations to the fantastic team at Birmingham for delivering equity of access to trials for people living with #MND. Supported by the wonderful @ADFoundationUK, Birmingham serves a diverse population, is a major regional recruitment hub, and one of 23 of our UK sites.
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21 Mar 2025
Our newsletter is back! Find out what’s been happening in MND-SMART over the past year with our Spring 2025 Newsletter: edin.ac/41OJ6td Join our mailing list to receive our bi-annual e-newsletter, showcasing all the latest trial updates: mnd-smart.org/news/newslette…

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19 Mar 2025
Platform trials have led to a significant step change in how we identify potential new treatments for #als #mnd Thank you to @ALSMNDAlliance for inviting @suvankarpal to present an update on progress we’re making alongside the #EXPERTS & #HEALEY platforms youtu.be/cg1Yon70eZ8?si=vHYT…
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MND-SMART retweeted
ALS/MND Platform Trials Update | March 19, 2025 📊 Many thanks to HEALEY, EXPERTS ALS and SMART! They will update us on their approach, recruitment, trial eligibility and their latest news. Appreciation to moderator, Martina de Majo. 🙏 👉 Register now: als-mnd.org/events-programs/…
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MND-SMART retweeted
Incredibly grateful to @mndsmart for leading this initiative and a warm welcome and huge thanks to our new Davidson Nurses 🙏🥰
14 Mar 2025
We are thrilled to launch our new 'Davidson Nurses' initiative in partnership with the @ADFoundationUK This special collaboration has established five regional hubs across the UK where dedicated nurses are working to promote equity of access to MND-SMART. mnd-smart.org/news/mnd-smart…
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14 Mar 2025
We are thrilled to launch our new 'Davidson Nurses' initiative in partnership with the @ADFoundationUK This special collaboration has established five regional hubs across the UK where dedicated nurses are working to promote equity of access to MND-SMART. mnd-smart.org/news/mnd-smart…
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MND-SMART retweeted
Wonderful Translational Summit on MND and Rare Dementias hosted by @lifearc1 this week. Great to hear about all the progress being made across multiple areas to improve outcomes for people and to join a panel session and update on progress with @mndsmart #RareNeuro
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