Well… this happened. Our recent research on brain vascular and white matter changes with aging just got covered by The Hindu! White matter isn’t just “wiring.” It reflects vascular health, resilience & biological ageing. thehindu.com/sci-tech/health… @iamvivekt @IISER_BERHAMPUR

Day 1: An exciting start! Got the opportunity to dive into MR sequence development—so much to learn and explore ahead. @NIBBRlab @iamvivekt

All excited for the Challenging Next 5-Days at Philips knowledge Innovation Centre, Bangalore, for packed 5 days of Ideation and MR Pulse Programming and Designing Workshop and Training. @NIBBRlab @iamvivekt @IISER_BERHAMPUR

📢 Hiring | Project Research Scientist–I (Medical) If you enjoy out-of-the-box thinking, pushing beyond comfort zones, and thriving on ambitious, cutting-edge neuroscience research challenges — there’s a place for you in our group. Apply by 12th Feb @iamvivekt @IISER_BERHAMPUR

Pleased to share that our recently published study has been featured in Biopatrika's Research Spotlight. Read it at: biopatrika.com/academia/rese… Research article: academic.oup.com/cercor/arti… @NIBBRlab @iamvivekt @iiser_berham

A Happy New Year from the NIBBR Group!🎆🎊 In frame: White Matter Tracts of a Cognitively Normal Subject, from IISER Berhampur Neuroimaging Cohort, acquired at our 3T MRI. @iamvivekt @NIBBRlab @IISER_BERHAMPUR

Same pinch Niraj; Equally excited. In this study, using multiple aging cohorts- including our @IISER_BERHAMPUR aging cohort- we demonstrate that periventricular white matter hyperintensity (PVWMH) volume increases nearly twice as fast with advancing age, with a clear inflection around 61 years. We identified that a PVWMH burden exceeding 2.3 mL, independent of chronological age, is associated with selective deficits in executive, attentional, and semantic cognitive domains, along with widespread cortical and subcortical atrophy involving the nucleus accumbens, rostral middle frontal, pre/postcentral gyri, lingual gyrus, and cerebral cortex. We emphasize that we age differently because we accumulate PVWMH differently-and once this burden crosses a critical threshold, it rewires the neuroanatomic and cognitive trajectories of aging. academic.oup.com/cercor/arti… Congratulations Niraj and Neha.

Deep WMH? Much less dramatic. DWMH had negligible effects compared with PVWMH. So location matters - not all WMH are equal. Think of PVWMH as damage near the central electrical hub. (6/n)

Why it matters? Once PVWMH exceeds 2.3 mL, the study found compromise in global fibre integrity; significant brain shrinkage in frontal, motor and visual areas; and deficits in attention, exec. func and semantic memory. Global screens (MMSE) barely budged - they miss this. (5/n)

WMH lesions grow exponentially with age, 2x faster near the ventricles than in deep white matter, with sharp rise at 61 years. (4/n)

What we measured: bright spots called white matter hyperintensities (WMH) on routine MRI. They come in 2 neighborhoods: PVWMH (near ventricles) and DWMH (in deep white matter). This multicohort study involved ~1500 subjects from NACC, ADNI and IISER Berhampur Aging Cohort. (3/n)

Insights: Even when cognitive tests say you're “normal”, your brain may tell a different story. Tiny small-vessel lesions, once they grow past ~2.3 mL, mark a sudden leap in brain aging-shrinking structure, slowing attention & semantic memory, and fraying axonal integrity. (2/n)

Even when cognitive tests say you're “normal”, your brain may tell a different story. Tiny small-vessel lesions, once they grow past ~2.3 mL, mark a sudden leap in brain aging - shrinking structure, slowing attention & semantic memory, and fraying axonal integrity.

Truly honored to present my research in the Young Scientist Colloquia (Tulsabai Somani Oral) at Indian Academy of Neuroscience #IAN2025. Great to see diverse and interdisciplinary neuroscience research from across India and beyond! @iamvivekt @NIBBRlab @IISER_BERHAMPUR

Thank you, ma’am. It was an honor to present my research to the neuroscience community, and I’m glad the idea and message came across clearly. @WormlockHolmes @IndAcadNeurosci #ian2025

If you're around and attending IAN 2025 conference, do visit my talk in Tulsabai Somani Award category today at 06:10 PM hosted by @RGCB_Trivandrum . @IndAcadNeurosci @IISER_BERHAMPUR

Pathetic! Air Asia (D7-0182) first delays the flight by 8 hours (intimated a day before), then makes the passengers stay in queue and waiting for eternity. Do these companies feel the plight of people or is it just a herd of animals for them? Who's to blame? @airasia

Exhilarated to share that I have been awarded with "Magna cum Laude distinction" from the International Society for Magnetic Resonance in Medicine (ISMRM) for our research work. @iamvivekt @NIBBRlab @IISER_BERHAMPUR