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Thomas Perlmann @perlmannlab

Members of Thomas Perlmann's group at Karolinska Institutet mostly tweet about exciting science and the Nobel Prize in Physiology or Medicine.

Joined September 2019
  • Tweets 334
  • Following 236
  • Followers 1,499
78 Photos and videos
Congratulations to @CharlesSwanton on winning the the 2026 Sjöberg Prize!🎉🎇 Check out the news here, including the short film from the Royal Swedish Academy of Sciences: kva.se/en/news/cancer-resear…

Cancer researcher is awarded Sjöberg Prize for describing tumours’ evolution

This year’s Sjöberg Prize of one million US dollars is awarded to a British cancer researcher who has provided fundamental knowledge about evolution in tumours. Charles Swanton, at the Francis Crick...

kva.se
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Impressive overview of previous and current work on nuclear receptors at Ron Evans Rolf Luft Award Lecture. The lecture was dedicated to the memory of David Mangelsdorf.
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Rare mutations in NR4A2 (Nurr1) offer unexpected insights into the causes of autism.
UCLA Neurology@UCLANeurology
19 Aug 2025
After years of unanswered questions, a rare NR4A2 gene mutation gave Franklin Henry and his family clarity, and sparked new research into the genetic roots of #autism. Now, he's helping @UCLAHealth researchers better understand how the brain develops. uclahealth.org/news/article/…
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Thomas Perlmann retweeted
Development@Dev_journal
28 Mar 2025
New insights into what makes midbrain progenitors tick Read this Research Highlight showcasing work from Laura Lahti, Thomas Perlmann @perlmannlab @karolinskainst and colleagues: journals.biologists.com/dev/…
A cross-section of embryonic day 13 mouse midbrain with immunohistochemical staining for nuclear factor I/B (Nfib; red), Sox2 (green) and tyrosine hydroxylase (blue).

ALT A cross-section of embryonic day 13 mouse midbrain with immunohistochemical staining for nuclear factor I/B (Nfib; red), Sox2 (green) and tyrosine hydroxylase (blue).

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Incredible research lecture by the brilliant @michelle_monje today at Nobel Forum! A true treat for a packed auditorium!
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Thomas Perlmann retweeted
The Royal Swedish Academy of Sciences@ScienceAcad_swe
13 Feb 2025
🌟Sjöberg Laureate discovered new targets for cancer therapies in the immune system!🌟 @MiriamMerad, Mount Sinai Health System, USA, has studied how cells in the innate immune system affect the body’s ability to fight tumours. Her discoveries have hugely contributed to making these cells a promising target for the development of new cancer therapies. She is now awarded the Sjöberg Prize, worth one million US dollars. 👉Learn more about the prize: kva.se/en/news/sjoberg-prize… @IcahnMountSinai @MountSinaiNYC
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Exciting new study from Mantas, Meletis and colleagues, demonstrating function of vulnerable DA neurons in procedural motor learning. Great work!
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Excellent presentations yesterday @NobelWeek in Nobel Forum @karolinskainst. Thanks to Jim Allison, Padmanee Sharma, Laurence Zitvogel, Mikael Karlsson, and Camilla Engblom!
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This year's Nobel Laureate harvest is now secured at Arlanda airport. Yesterday: Gary Ruvkun, Natasha Staller, and Victoria Ruvkun. Today: Victor Ambros and Rosalind Lee. With Nobel Attachés August Borg, Anna Wikner, and drivers.
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A new preprint from our lab is now online in Biorxiv. Thread 1/5 doi.org/10.1101/2024.11.12.6…

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The ependymal derivatives of mDA progenitors in the adult retained several mDA progenitor characteristics but also expressed, e.g., Pdyn, the precursor of opioid peptides. These specific ependymal cells might form a novel type of circumventricular organ. 4/5
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Thanks to Michael Piper, Richard Gronostajski, and all other authors for their contributions! 5/5
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Great meeting in Utrecht today! Many thanks for the opportunity to participate!
UU No Guts No Glory@UUNoGutsNoGlory
1 Nov 2024
Here today at @DPSConference24 , fascinating keynote from @perlmannlab all about dopamine neurons and their origins #parkinsonsdisease
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…. and only around 14 hours until the famous call from Stockholm. Here’s the phone I’ll use. If you expect the call, please stay alert @ around 9.30-10 CEST tomorrow!
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In about 24 hours, the votes from Nobel Assembly members will be collected in this brass bucket. Welcome to watch the announcement of the 2024 Nobel Prize in Physiology or Medicine @NobelPrize CEST 11:30 am!
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...followed by dinner with science legend, Joe Goldstein.
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It was great participating in this year's @LaskerFDN award ceremony! Mike Brown introduced James Chen to the basic award for the discovery of cGAMP/cGAS.
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Such a pleasure being your collaborator, Ioannis! Great work!
Ioannis Mantas@Ioannis_Mantas
18 Sep 2024
I am pleased to share our publication on the crucial role of Nurr1 in modulating the response to hallucinogens in the claustrum. A huge thank you to @perlmannlab, @giacomello_lab, @CarlenLab and @Boehringer #Claustrum #Nurr1 #Hallucinations nature.com/articles/s41467-0…
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