Staff Scientist at FZ Jülich @SachseGroup Enjoy cold microscopy, fancy pixels and loud music. Zerforschen!
Joined May 2018
- Tweets 234
- Following 350
- Followers 388
- Likes 1,567
70 Photos and videos
16 Feb 2024
my band SSB dropped a new EP today. Let me know what you think :) open.spotify.com/intl-de/alb… #SheSaidBattlecatNotSingleSideBand
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7 Dec 2023
New research from our lab! nature.com/articles/s41467-0… Atg18 oligomer organization in assembled tubes and on lipid membrane scaffolds
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20 Nov 2023
Postdoc Position – Method development of cryogenic 4D-STEM imaging fz-juelich.de/de/karriere/st…
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15 Nov 2023
Cryo correlative light and electron microscopy (CLEM). #b3d cover suggestion for Bioprotocols 2023
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10 Oct 2023
We tried to measure #CryoEM ice thickness via @CryoSolWorld VitroJet. Excited about your feedback on biorxiv.org/content/10.1101/…
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22 Aug 2023
Interested in doing #CryoEM in NRW/Germany? Join my talk next wednesday at @ruhrunibochum @grk2341 to learn how you may solve your structure at ER-C @fz_juelich kalender.biologie.ruhr-uni-b…
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12 May 2023
Learning AutoScriptTEM and fascinated by having Titan Krios in a Python shell. Deep dark thoughts: SI units are great and intuitive, but what happens when I forget the e-6 for defocus?
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27 Apr 2023
new paper: "ATP binding and ATP hydrolysis in full-length MsbA monitored via time-resolved Fourier transform infrared spectroscopy"
doi.org/10.1515/hsz-2023-012…
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27 Apr 2023
I now work in CryoEM, but still find the method of time resolved FTIR spectroscopy most elegant. Looking at protein reactions label free, with ms time resolution and sub-angstrom spatial resolution. CryoEM is not quite there (yet) :)
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14 Apr 2023
Deploying another 1.6 petabytes for electron microscopy data processing. So many drives..
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14 Apr 2023
Ernst Ruska Centre featured in Biophysical Society TV youtube.com/watch?v=34PglAv2…
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2 Mar 2023
🚨NEWS ALERT🚨I am starting my lab at @fz_juelich to study mitochondrial membrane proteins and I’m recruiting PhD students! Please apply/RT/contact me if you have questions. PhD Position – Cryo-EM of mitochondrial membrane protein complexes fz-juelich.de/en/careers/job…
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26 Jan 2023
EMPIAR.org/EMPIAR-11034 shows scanning transmission electron microscopy (STEM) using the integrated differential phase contrast mode known as iDPC–STEM applied to a cryo-EM specimen by @SachseGroup @fz_juelich. Published @naturemethods doi.org/10.1038/s41592-022-0…). #EMPIAR #cryoEM
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7 Dec 2022
Model building with a fluff. She's concerned about the correct conformations though. #guineapiginscience #cryocarrot #cryoEM #ribosomes
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7 Dec 2022
7/12 for all the millenials out there❄️🔬🐩🐺
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1 Dec 2022
The Sachse lab advent calendar is back! We will post a festive/jolly/strange EM picture every day until Xmas!🎄✨ 1/24
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5 Sep 2022
Our iDPC-STEM manuscript is now published in Nature Methods doi.org/10.1038/s41592-022-0… We used scanning transmission electron microscopy to resolve vitreous cryo samples of TMV and KLH to resolutions of 3.5 and 6.5 Ang. 1/4
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27 Jul 2022
Our most recent Atg18 preprint is now available on BioRxiv!
27 Jul 2022
New research from our lab! We elucidated how Atg18 oligomers form structural scaffolds for membrane interaction. Lots of #CryoEM structures (Helical assemblies, SPA, subtomo) suggest a conserved interaction motif for Atg18-Atg2
biorxiv.org/content/10.1101/…
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