We are a lab at University of Pennsylvania @pennvet investigating host-pathogen interactions.
Joined November 2019
- Tweets 185
- Following 76
- Followers 762
- Likes 409
33 Photos and videos
Pinned Tweet
19 Oct 2023
Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity science.org/doi/10.1126/scit…
19 Oct 2023
A #translational study evaluating the role of #skin #microbiome in driving IL-1b #immunopathology in a parasitic infection, cutaneous #leishmaniasis.
@hostmicrobe @tpsinglab @novaislab @LovinsTori @pscottlab @HarrisOnTheSkin #eGrice science.org/doi/10.1126/scit…
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Scott Lab retweeted
2 Jan 2024
Come to work in a GREAT multidisciplinary team @Penn super interested in Host-Pathogen interactions and cutting-edge high-throughput NGS single-cell technologies #JobAlert #Bioinformatician💻🐛🧫
23 Dec 2023
Start your New Year with a new job! We're hiring a bioinformatics specialist to lead analyses of single cell genomic data 💻. Great opp. to work w/ a large and interdisciplinary team of immunologists and infectious disease researchers. Apply below!
bit.ly/3GUY9Hz
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Scott Lab retweeted
23 Dec 2023
Start your New Year with a new job! We're hiring a bioinformatics specialist to lead analyses of single cell genomic data 💻. Great opp. to work w/ a large and interdisciplinary team of immunologists and infectious disease researchers. Apply below!
bit.ly/3GUY9Hz
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Scott Lab retweeted
23 Oct 2023
Findings by @tpsinglab @pscottlab and colleagues @pennvet @PennMedicine have clinical ramifications for cutaneous leishmaniasis and other skin diseases associated with a dysregulated microbiome when Tregs are limited or dysfunctional. bit.ly/3MgOlen
#InfectiousDisease
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Scott Lab retweeted
24 Oct 2023
Insights: Michail Lionakis @LionakisLab @NIAIDNews discusses study from @tpsinglab, @pscottlab et al. (bit.ly/3MgOlen) showing that Rorγt regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth: bit.ly/48Y7iMy
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Scott Lab retweeted
28 Jan 2023
Learned more about S. aureus as editor of this excellent review @WolfDermGraz @PennSbdrc @pscottlab
Microbial derived antimicrobial peptides as potential therapeutics in atopic dermatitis frontiersin.org/articles/10.…
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Scott Lab retweeted
19 Oct 2023
This cover is amazing! Our recent publication is here! Evaluating the role of #skin #microbiome in driving IL-1b #immunopathology in cutaneous #leishmaniasis
18 Oct 2023
The new special issue on zoonotic diseases has arrived! Articles this week explore the latest research and counterstrategies for zoonotic threats, including an Editorial from Anthony Fauci and research on how the skin microbiome influences leishmaniasis.
scim.ag/4vr
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Scott Lab retweeted
18 Oct 2023
We highlight how the human microbiome can shape disease outcomes in cutaneous leishmaniasis and suggest pathways toward host-directed therapies to mitigate the inflammatory consequences. Nice work @amorim_cfa @microbiome @RNAseq @immunology
science.org/doi/10.1126/scit…
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Scott Lab retweeted
16 Oct 2023
Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis, say Tej Pratap Singh @tpsinglab, Phillip Scott @pscottlab and colleagues @pennvet @PennMedicine: bit.ly/3MgOlen
#InfectiousDisease #HostDefense
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Scott Lab retweeted
17 Oct 2023
Tregs tame skin bacteria and IFN-γ-associated pathology. Michail Lionakis @LionakisLab @NIAIDNews discusses recent study from @tpsinglab, @pscottlab et al (bit.ly/3MgOlen) in new Insights: bit.ly/48Y7iMy
#InfectiousDisease #HostDefense #Tolerance
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Scott Lab retweeted
19 Oct 2023
A #translational study evaluating the role of #skin #microbiome in driving IL-1b #immunopathology in a parasitic infection, cutaneous #leishmaniasis.
@hostmicrobe @tpsinglab @novaislab @LovinsTori @pscottlab @HarrisOnTheSkin #eGrice science.org/doi/10.1126/scit…
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Scott Lab retweeted
10 Oct 2023
Insights from @LionakisLab: Mibrobial dysbiosis worsens cutaneous leishmaniasis. @tpsinglab, @pscottlab et al (bit.ly/3MgOlen) show that Rorγt regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth bit.ly/48Y7iMy
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Scott Lab retweeted
10 Oct 2023
Insights @JExpMed by @LionakisLab: Mibrobial dysbiosis worsens cutaneous leishmaniasis. @tpsinglab, @pscottlab et al (bit.ly/3MgOlen) show that Rorγt regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth bit.ly/48Y7iMy
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Scott Lab retweeted
11 Oct 2023
We appreciate immensely the @LionakisLab, for your insights on our recent work showing that Foxp3 Rorγt Tregs suppress pathogenic IFN-γ responses to control S. aureus growth @tpsinglab @pscottlab #eGrice
10 Oct 2023
Insights from @LionakisLab: Mibrobial dysbiosis worsens cutaneous leishmaniasis. @tpsinglab, @pscottlab et al (bit.ly/3MgOlen) show that Rorγt regulatory T cells suppress pathogenic IFN-γ responses to control Staphylococcus aureus growth bit.ly/48Y7iMy
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10 Oct 2023
Led by @tpsinglab, collab with @amorim_cfa, @LovinsTori , Charles Bradley, Carvalhos labs and Elizabeth Grice 🧫
#translationalresearch #infectiousdiseases #inflammation #immunology #Tcell #bacteria #parasite #omics #DualRNAseq #datascience #datamodeling #clinicaloutcome
9 Oct 2023
Study by Singh, Scott et al. @PennMedicine involving mice and #Leishmania braziliensis patients reveals that Treg levels function as a rheostat, controlling bacteria in the skin & influencing whether bacteria induce IL-17 or IFN-γ-mediated immunopathology. bit.ly/3MgOlen
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Scott Lab retweeted
3 Oct 2023
Looking to study parasites for your PhD training? Join us a Penn! Great breadth cell biology, genomics, immunity, drug and vaccine development. Great labs & environment! @KingOfPathogens @yiweichang @odomjohnlab @DeBroski1 @hostmicrobe @PoveLab @omartheharb @pscottlab @dsro5os
We are pleased to announce that we are now accepting BGS applications for Fall 2024 until December 1st! Please see our Admissions page for more info and how to apply: med.upenn.edu/bgs/phd-applic…
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Scott Lab retweeted
9 Oct 2023
Leishmania braziliensis patients & mouse models reveal that Treg levels function as a rheostat, controlling bacteria in the skin and influencing whether bacteria induce IL-17 or IFN-γ–mediated immunopathology @JExpMed @pscottlab
doi.org/10.1084/jem.20230558
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Scott Lab retweeted
12 May 2023
ok @CytokineSociety members @ImmunologyAAI stop by booth and learn about the annual meeting in Athens
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Scott Lab retweeted
26 Apr 2023
A great meeting for our family of immuno•parasitologists at the Woods Hole Conf 2023 🦠🪱
I got awards for our current study!
@novaislab @pscottlab #DrAlanSher @MBLBoP @tpsinglab @LovinsTori #DrElizabethGrice @WHIP42266646
#Immunology #parasites #microbiome #science
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Scott Lab retweeted
25 Apr 2023
Being Dr. Alan Sher's scientific granddaughter is a real privilege and honor. Today I had the opportunity to hear again what I've been learning from @pscottlab over the years: "The parasites teach us a lot about immunology." at @MBLScience @MBLBoP @WHIP42266646
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