Associate Professor of Molecular Microbiology at Washington University in St. Louis. Interested in virology, gut, innate immunity, movies, and hiking
Joined July 2017
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3 Mar 2025
Excited to share the first paper from our lab in 2025! cell.com/cell-host-microbe/f…. Herculean effort by @gaopenghou, the paper demonstrates that UV-inactivated replication-defective rotaviruses can cause diarrhea in neonatal mice.
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Jun 3
Happy to share our new manuscript out to day in @PNASNews Great effort by Cherry, this paper seeks to understand the mechanisms by which rotavirus NSP1 targets IRF3 for proteasomal degradation. A great collaboration with @WeitzmanLab pnas.org/doi/10.1073/pnas.25…
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May 29
This year’s Michelson Prizes: Next Generation Grants is now open! Great opportunity for early career vaccine researchers: michelsonprizes.smapply.org
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May 27
Excited to share this review article from an MSTP student in my lab Avan: journals.plos.org/plospathog…. Avan has another seminal paper on the role of M cells in rotavirus infection and vaccination. Stay tuned!
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Apr 21
Farewell party for my very talented postdoc Gaopeng Hou, who is starting his own lab at Nanjing University! A bittersweet moment and a real milestone for the lab!
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Apr 8
Cannot be more proud of my MSTP student Avan who gave an exemplary thesis defense and took the lab in a whole new direction! We will miss you so much! Wishing you all the best with the clinicals!
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Mar 20
Happy to share our new manuscript out today in @PLOSPathogens. We showed that in addition to flaviviruses and HTLV-1, rotavirus also utilizes an ER-resident SPCS complex for glycoprotein VP7 signal peptide cleavage and maturation. journals.plos.org/plospathog….
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Feb 17
Our lab at Washington University School of Medicine is hiring a Senior Research Technician!
We are looking for a highly motivated scientist, ideally with animal work experience, to join our enteric virus team!
Interested? Apply here:
wustl.wd1.myworkdayjobs.com/…
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23 Dec 2025
We are looking for new colleagues in our department! Come and join our vibrant microbiology community! Please RT.
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3 Sep 2025
Thrilled to share another paper that came online today in @PNASNews. Enkai in our lab showed that 2-hydroxy very-long-chain fatty acids play an essential role in regulating the entry of viruses and bacterial toxins that commonly rely on endosomal calcium. pnas.org/doi/10.1073/pnas.25…
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7 Oct 2025
Great to see our story recognized by the WashU medicine news: medicine.washu.edu/news/rese…
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2 Oct 2025
Gave two talks in the past five days, but the true highlight of the week was seeing Mary Estes introduce Harry Greenberg for the Ruth Bishop Lecture in Cape Town! It’s deeply inspiring to see giants of virology remain so engaged and impactful.
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25 Sep 2025
A good read for those interested in mucosal vaccines: wellcomeopenresearch.org/doc…
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19 Sep 2025
Excited to share that I have been promoted to Associate Professor with tenure! Deepest thanks to my past and present trainees, dept chair Dr. Whelan, formal and informal mentors, colleagues, and collaborators for their support over the past six years. I am truly grateful!
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29 Aug 2025
Happy to share our new manuscript out today in @NatureComms Great effort by @YinxingZhu, the paper demonstrates that the host prefoldin complex positively regulates ISG expression, which rotavirus VP3 protein antagonizes. rdcu.be/eC28K
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29 Aug 2025
A great collaboration with Peter Jackson at Stanford and BV Prasad at Baylor College of Medicine. @WUSTLnews @washumedicine
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22 Apr 2025
We identified SAMD9 as a common sensor of cytosolic dsDNA and dsRNA molecules and a key host restriction factor of the infection of multiple dsRNA viruses in vitro and in vivo!
rdcu.be/eiJHa
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18 Jul 2025
WashU medicine news on our paper and implications: source.washu.edu/2025/07/was…
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18 Jul 2025
Another year of ASV! Really enjoyed Montreal and catching up with friends and colleagues despite the flight delays. Avan from my lab gave a fantastic talk on rotavirus and M cells!
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14 May 2025
Great opportunity to obtain additional funding and publicity for your work! Don't miss out!
Applications are now being accepted for the Michelson Prizes: Next Generation Grants!
We’re seeking applicants who are deepening our understanding of human immunology and uncovering new approaches to combating diseases.
All early-career investigators, postdocs, clinical fellows—including residents and interns—and other researchers in training are eligible to apply!
Learn more: michelsonmedicalresearch.org…
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Siyuan Ding retweeted
Applications are now being accepted for the Michelson Prizes: Next Generation Grants!
We’re seeking applicants who are deepening our understanding of human immunology and uncovering new approaches to combating diseases.
All early-career investigators, postdocs, clinical fellows—including residents and interns—and other researchers in training are eligible to apply!
Learn more: michelsonmedicalresearch.org…
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24 Apr 2025
Congratulations to Juhee on a stellar thesis defense! Clear, thoughtful, and thorough. Your work on rotavirus and SARS-CoV-2 reflects incredible perseverance. It's been a privilege watching you grow into an independent scientist. Wishing you all the best in your next chapter!🎓👏
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