Supply Chain Design, Technology, and Data Analytics for Development
Joined June 2009
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43 Photos and videos
Moltbook should be closely followed by @JoHenrich. His “Secret of Our Success” argued prestige was humanity’s key for cultural learning. We got smart by getting good at figuring out who to learn from.
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What will evolve as status mechanisms (equivalent to dominance and prestige) in AI societies?
And how operationalized? Reputation networks? Compute access? Benchmark scores?
@sebkrier @tylercowen @ATabarrok
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Sidharth (Sid) Rupani retweeted
16 Nov 2025
So this is public now, so: I’m officially starting a Works in Progress-style magazine focusing on the developing world!
It is called In Development, and first call for pitches will be coming at the end of the year.
16 Nov 2025
Emergent Ventures winners 48th cohort marginalrevolution.com/margi…
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LAUNCH DAY 🚀 Today I’m launching a new podcast, Hard Drugs, with Jacob Trefethen (@JacobTref)
Our first episode is about lenacapavir — a new HIV drug that blocks infections with an efficacy rate of nearly 100%, and which could completely change the fight against HIV worldwide.
It’s also about the scientific journey leading up to this point, and how HIV was transformed from a lethal to a manageable condition.
3:52 How was HIV discovered? Where did it come from, and how does it attack the body and cause AIDS?
38:10 Antiretrovirals: How did scientists develop breakthrough HIV drugs — from azidothymidine to protease inhibitors to PrEP?
1:51:35 How does prevention and treatment work today?
2:19:03 HIV’s capsid and the breakthrough of lenacapavir, the first-approved HIV capsid inhibitor
2:50:36 How to develop long-lasting treatments
3:14:45 Lenacapavir’s near 100% efficacy in clinical trials
3:48:40 The impact of global programs against HIV, and can we now end HIV?
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2 Aug 2024
Rave Book Review.
Nicola Twilley's (@nicolatwilley) 'Frostbite' is a fascinating dive into the cold-chain, the vital role of cold infrastructure in global supply chains. It's a brilliant blend of engaging storytelling, deep research, and conceptual thinking.
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2 Aug 2024
So many more fascinating nuggets on:
- refrigerator design,
- optimal storage conditions for different kinds of fruit,
- the technology behind orange juice,
- food labels and more.
Just good stuff.
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2 Aug 2024
If you loved Daniel Yergin's (@DanielYergin) "The Prize" or Marc Levinson's "The Box", you’ll find Frostbite compelling. But more broadly, as the book jacket says, it actually is "essential reading for anyone who eats or drinks in the 21st century." :-)
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18 Jul 2024
Insightful and well thought-through essay (with useful frameworks) on where the African startup and VC landscape is today.
15 Jul 2024
African VC has shifted post-ZIRP. There's a conviction dead zone. We need to get back to first principles.
Here's an update to what we're thinking about @TheDFSLab. It's time to state our convictions about the market and the shape of the opportunity.
medium.com/dfs-lab/africas-s…
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5 Apr 2024
RT @devex: By mapping and analyzing diagnostic networks across different locations, the Philippines has made significant strides in optimiz…
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Brazil is using Wolbachia in 6 new cities to address a rising dengue outbreak.
“We have a list of more than 50 municipalities that have got in touch requesting [‘wolbitos’],” “Our biggest bottleneck right now is the production of mosquitoes.”
theguardian.com/global-devel…
New study on the impact of Wolbachia release programs to reduce dengue in three Columbian cities.
The authors find a 95–97% decline in dengue incidence compared to previous years, including adjustment for seasonal trends.
journals.plos.org/plosntds/a…
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Sidharth (Sid) Rupani retweeted
15 Jan 2024
The decline of air pollution in Beijing.
Massive health benefits for its citizens.
From @davidfickling: bloomberg.com/opinion/articl…
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A fun new diagram and article I wrote recently.
“Why isn't it possible to sum up deaths caused by different risk factors?”
This problem is frequently overlooked, which means people don't realise that the same deaths can be prevented in multiple ways. ourworldindata.org/why-isnt-…
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Sidharth (Sid) Rupani retweeted
22 Sep 2023
"In East Africa, between 2017 and 2021, the industry tripled in size, according to a report by @GatsbyAfrica ."
bbc.com/news/business-667889…
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1 Jul 2023
RT @devonzuegel: The saga of Israeli water management is one of the most inspiring stories of the last 75 years
Israel went from having a…
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Sidharth (Sid) Rupani retweeted
20 Mar 2023
My heart is breaking for those affected by #CycloneFreddy. Malawi's death toll is at 476. Almost half a million are displaced, around 350 missing, and 900 injured. The ongoing cholera outbreak looks set to spiral. A 🧵w/ latest updates and ways you can support relief efforts:
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