Hi Everyone, @bryan_johnson is in India. And longevity is the new buzzword. Only one of these statements is true. In 2020, I realised my body was older than I could’ve comprehended. And that's where my story begins. In July 2020, I got COVID. A full body check-up that year revealed a few things – High cholesterol High triglycerides Low B12 (126 pg/ml) Low D3 And pre-diabetic. I took the first steps – reduced my alcohol consumption and focused on nutritious meals. Despite the LOW FODMAP diet, my stomach issues escalated. Another round of tests (endoscopy and ultrasound) told me that I was a walking store of diseases. A bacterial infection H. Pylori. Ulcer. Fatty liver. GERD. Villous atrophy. The standard protocol for H Pylori infection is to take 14 days of antibiotics, four antibiotics every day. I did that. And I felt better for some time. Until I lost 11 KGs in 1 month is not. While having 3 large meals and 2 snacks. No calorie deficit of any kind. I did another round of tests to rule out Tuberculosis and the deadly C word. The tests came out negative and my gut was in very good shape. The doctor said it was in my head. Anti-depressants were an option (took them for 3 days) but I still felt miserable. I needed answers. This was when I came across systems biology (I was clear that it was the future of health care). Did a metabolomics test and - Mitochondrial dysfunction Lactate of pyruvate ratio was 338 (it should be 10-20) IBS diarrhoea. Low platelet levels and a rate of decline of 10K X 10^3/ uL per month The traditional sickcare model was failing me. So I went back to studying. And got in touch with a functional medicine expert in India. For the first time in 18 months, I was equipped with more data and a personalised protocol that looked VERY different from 4 nutritionists and 5 doctors I worked with. Cut to 2023, my biomarkers were in the optimal range (and continue to be today). I stopped taking most of my supplements. My stomach was healed. My absorption started to get better. My B12 – 432 pg/ml. The “personal” spilled into work. And this time, it wasn’t a sabbatical but the second stint of life. I met my co-founders @gehani and @sanmaya , and we set out to find a deeper thesis on what it will take to build a world-class longevity startup out of India. In the last few months, we’ve run pilots with real users by getting them to do blood tests on 150 biomarkers and working closely with them to understand their issues. Majority of the users? Diabetes. Gut issues. Auto-immune conditions. Cardio-vascular issues. It told us one thing – 30s are the new 50s. Today, we’re designing a system for a long life. Only for the people who know they want to live a long life and are here to find out how. Thanks to @bryan_johnson, the world is ready for this! P.S. He is in India this week and speaking in Mumbai today with @deepigoyal. Not a better day than this to launch FOXO and make Indians live longer and unlock Life .

One of the best 10K I spent in my life. @skipiit is on a mission fuelled by personal experience, and I am super bullish.

Over the years, I’ve realized how much our health story is hidden inside routine blood reports — and how little most of us actually understand beyond “normal” or “abnormal.” I recently explored FOXO Primer by FOXO, and the experience felt very different from a standard health checkup. What stood out to me wasn’t just the volume of biomarkers, but the way the entire assessment connected the dots across different systems of the body. Instead of isolated numbers, the focus was on understanding patterns, lifestyle impact, inflammation, recovery, and long-term health risks in a much more holistic way. Most advanced testing options usually feel: too fragmented, too expensive, or too difficult to interpret meaningfully. This felt more structured and actionable. I also found the larger vision behind FOXO interesting shifting healthcare from reactive treatment to earlier understanding and prevention. That direction makes a lot of sense for where healthcare is headed globally. If you’re someone who likes understanding your health deeper than a basic annual test, this is definitely worth exploring: FOXO Primer(foxo.club/) @skipiit @emeetab @FOXOclub

Thanks @vaibhavbetter for the kind words and one of the apt description of what we are building at @FOXOclub

Applications closing tonight! If you're building in hard tech and frontier sciences in India...rockets, robots, fusion, biotech, semis, physical AI and all that, you should be apply to compete at Curiosity 2026 by @spc_india. ₹1.25 Cr in grants, $85k in OpenAI credits, live demos and booths for showcase. It's time for the hard-mode builders in India, to have a platform like this. See you there. Apply here southparkcommons.com/curiosi…

Completing the Health Spectrum series, Subhendu writes about the Health Trifecta: lifestyle, biomarkers, and symptoms.

If you want to feel like a teenager, have a drink with your college friends. If you want to feel geriatric, meet a sports physio.

Health isn't binary. The mistake is trying to fix everything. The move is to find the two or three axes that are actually drifting and spend your effort there. #Under60Seconds #FOXO #Longevity #Healthspan #PrecisionLongevity

Women, you are running four entirely different metabolic programs every month. That intense carbohydrate craving on day 23? It’s not a lack of willpower; your energy demand is genuinely higher. Tap the screen to pause on your current phase and get your targeted protocol!

You are optimising the wrong end of the night. We wrote about why sleep researchers now consider wake time and morning light the strongest levers for re-anchoring the circadian clock. And why the fix most people skip is also the simplest one.

Hello Xverse, I want to get connected to the best of the best personal trainers in India. If you know anyone please tag them here. Repost for good karma! @iam_supratik999 @chiragbarjatya @vivekguptaa

Welcome back, Superman! Best wishes! With @skipiit & @spatro 🇮🇳

2025 did something special: it made longevity science harder to fake. Even the most advanced research kept pointing back to the same foundations - sleep, exercise, metabolic health, recovery. We unpacked what changed. Link in the thread.

Major updates on blrbloom.com 🌸🌼 - Added ~15000 yellow blooming trees 🌼 from BBMP data. Now ~43000 trees to explore. - Now explore and spot both pink and yellow easily Please share feedback and experience (still wip). Image from Cubbon park last week.

Updates on blrbloom.com 🌸 - BBMP census layer now shows 28K trees, up from ~21K - Redesigned bottom navigation - Client-side image compression

🌸🌸🌸🌸🌸🌸🌸🌸🌸🌸 A crowd-sourced Tabebuia bloom tracker for Bengaluru. Spot, share & explore Pink Bengaluru! blrbloom.com/#about

"Mitochondria is the powerhouse of the cell." Yes. But it's also an ancient bacteria that does so much more in your body than you know, and the result of an accident gone right, making all complex life possible. The science is astonishing. The origin story, even better.

Final set of founders: → Confido Health (Fund V) - Chetan & Vichar putting AI voice administrators in US medical practices 1M tasks monthly | 50 customers | 1.7M patients served in <1 year Each saved call = $300 in revenue. → Mave Health (Fund V) - Dhawal Jain, Jai Sharma & Aman Kumar building wearables for mental wellness Designed to improve mood, sharpen focus, and regulate stress. → FOXO (Fund IV) - Subhendu, Akash & Sanmaya building a closed-loop longevity platform Members gaining 5 extra years of healthspan | Biological aging slowed to <90% usual rate Preventing chronic disease before it starts. Making humans live stronger, longer. @confidohealth @mavehealth @skipiit @gehani @sanmaya @thatssodhawal @jsjai3009 @amankrsingh03 @vichar_shroff @mchetanreddy500 #BlumeDay2026 #TheOrbitsAreShifting

If supplements are already part of your routine, pause and ask: What job are you hiring this supplement to do? Prove the need (so you’re not guessing) Support absorption first (so your body can actually use it) Match the compound to the job (right form, context, and dose)

Healthspan is often confused with being "disease-free”, but a more useful definition is capacity. Can you think clearly? Can you move without limitation? Can you do the things that matter to you, reliably, year after year?