@VanderbiltMSTP student interested in inflammation in cardiovascular disease. Longhorns, Mavs, film, and music.
Joined July 2011
- Tweets 67
- Following 243
- Followers 217
- Likes 812
Photos and videos
Duncan Smart PhD retweeted
18 Feb 2024
Single subcutaneous doses of zilebesiran significantly lower blood pressure for up to 6 months, suggesting potential for use as an effective antihypertensive with quarterly or biannual dosing.
Read the KARDIA-1 RCT:
ja.ma/48jbBAy
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Duncan Smart PhD retweeted
29 Nov 2023
Looking forward to working with @MichaelR21 @JeffHsuMD and @VasRes to learn about all the exciting translational work coming out of #JACCBTS!
27 Nov 2023
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To cap the thread off on a personal note, I am excited to join the #JACCBTS team as a Social Media Consultant along with @Jean_Wassenaar! Follow us for more tweetorials on future articles from the journal! @JeffHsu @VascRes
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Duncan Smart PhD retweeted
28 Nov 2023
Excited to join the #JACCBTS social media team—it has quickly become a journal in which to find and publish high-quality cardiovascular research.
Follow the entire team for more great work published in #JACCBTS! @JeffHsuMD @VascRes @Jean_Wassenaar @JACCJournals
27 Nov 2023
We still have no medical therapy for aortic stenosis, but in this month’s issue of @JACCJournals #JACCBTS, Han, et al. take us closer to possible pharmacologic targets as they define the role of PALMD in aortic valve disease. 🎯
Come along as we take a look! 🧵 1/11
ALT Title page and visual abstract of a paper entitled "Palmdelphin Deficiency Evokes NF-kB Signaling in Valvular Endothelial Cells and Aggravates Aortic Valvular Remodeling"
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Duncan Smart PhD retweeted
27 Oct 2023
Thank you @CVR_TomaszGuzik and @ESC_Journals for highlighting our recent publication with this invited editorial! academic.oup.com/cardiovascr…
@smartdunc @DJFehrenbach @AmandaDoranLab @Jean_Wassenaar #HeartFailure #Trem2 #cardioimmunology
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Duncan Smart PhD retweeted
18 Oct 2023
When Einthoven introduced the ECG to the world, he uniquely labeled its parts PQRST, inspired by mathematicians who used Ps & Qs in coordinates. Yet, he believed there was more to find, so he started in the alphabet's middle, leaving room for new discoveries on both sides.
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25 Sep 2023
Woah. CCR2 myeloid cell imaging in the human heart. Can’t wait to see this applied more broadly in CV diseases. Amazing work from Lavine at al. Great example of translating mechanistic preclinical findings to humans
25 Sep 2023
RESEARCH| Lavine et al. establish the feasibility of C-C chemokine receptor 2 (#CCR2) #imaging, a marker of inflammatory monocytes/macrophages, in patients that suffered a #MyocardialInfarction| @LavineLab, Yongjian Liu, @WUSTL nature.com/articles/s44161-0…
👉rdcu.be/dmYvv
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Duncan Smart PhD retweeted
29 Aug 2023
Cardiometabolic Effects of DOCA-salt in Mice Depend on Ambient Temperature @JLGrobe @fekete2003 @nakagawapablo @curtsigmund
ahajrnls.org/45tWDH0
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Duncan Smart PhD retweeted
1 Aug 2023
Celebrating our transitions and next steps #Madhur Lab #Alexander Lab #WillMissThisGang!! @DJFehrenbach @smartdunc @Jean_Wassenaar @VascRes @VUMC_MedPSTP @VUMC_Medicine @VUMCClinPharm #GreenHillsGrille
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Duncan Smart PhD retweeted
23 Jun 2023
First oral semaglutide made a strong impression in OASIS-1 #obesity with 15% #weightloss now orforglipron leads the impressive pack of new small molecule oral GLP-1RA with robust #Weightloss and good tolerability ADA2023
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14 Jun 2023
Many thanks to all my coauthors who made this possible! Excited to share this story in its final form
14 Jun 2023
@smartdunc's first first-author paper is finally in press! @CVResearch "Immune profiling of murine cardiac leukocytes identifies Trem2 as a novel mediator of hypertensive heart failure" shorturl.at/gG123 @CVimmunology @Jean_Wassenaar @AmandaDoranLab @VAgrawalMDPhD
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Duncan Smart PhD retweeted
18 Apr 2023
Clinical benefits of #SGLT2is in #HF do not appear to be mediated by changes in myocardial #energetics based on this small mechanistic RCT conducted in
patients with #HFrEF & #HFpEF
#EMPAVISION ahajournals.org/doi/10.1161/…
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Duncan Smart PhD retweeted
Join us in one week as @ThaoDVLe, graduate student in the lab of Julio Ayala (@TheBurro34), defends her thesis titled "Identification of Intracellular and Physiological Targets Transducing the Weight-Lowering Actions of Glucagon-Like Peptide 1 Receptor Agonists!"
@VanderbiltMSTP
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30 Mar 2023
Excited to see this officially out!
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Duncan Smart PhD retweeted
23 Mar 2023
Hypertension is the leading modifiable risk factor for worldwide morbidity & mortality. This study describes the role of T cells in hypertension & hypertensive end-organ damage & outlines potential therapeutic targets bit.ly/KID090
@DJFehrenbach @VascRes @CVimmunology
ALT Potential pathways to target to modulate T cell phenotype in hypertension.
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22 Mar 2023
Excited to share a portion of my thesis work soon! For those who can’t attend in person, please reach out and I will share a zoom link!
In two weeks @smartdunc, a graduate student in the lab of Meena Madhur, will defend his thesis titled "Inflammation in hypertensive cardiac remodeling and heart failure."
We can't wait to see you there and here all about this work!
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Duncan Smart PhD retweeted
15 Mar 2023
1/ We are delighted to see our study on the effect of sucralose on T-cells was published today in @Nature!
Time for a tweetorial 🧐 (with GIFs 🤠)
15 Mar 2023
A study in @Nature finds that high doses of the sweetener sucralose reduce immune responses in mice. The findings do not provide evidence that normal sucralose intake may be immunosuppressive. go.nature.com/42fnJ3p
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Duncan Smart PhD retweeted
21 Dec 2022
#OriginalResearch: In a meta-analysis of 8 studies, 6,000 to 9,000 steps/day was associated with 40% to 50% lower risk of CVD among older adults #AHAJournals ahajrnls.org/3WgtECd
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Duncan Smart PhD retweeted
21 Dec 2022
The median time of onset of ICI-myocarditis is ~30-60 days
In our patient, it occurred at 987 days
We report a case of fulminant late onset ICI-myocarditis. Hoping to raise awareness for late onset irAEs @HanZhuMD @SeanM_Wu @Ron_Witteles @JACCJournals
jacc.org/doi/10.1016/j.jacca…
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Duncan Smart PhD retweeted
15 Dec 2022
Thanks @nanostringtech for selecting me for the grant, can’t wait to use the CVD pathophysiology panels to advance my research!
12 Dec 2022
👏 to our North America nCounter CVD Pathophysiology Panel Grant Program Winners: Jean Wassenaar, MD Ph.D. of @VanderbiltU Medical Center & Steven Goldman, Ph.D. of @uarizona Sarver Heart Center.
Check out this Brief nCounter with the CVD Panel 👉 bit.ly/3WcDogk
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Duncan Smart PhD retweeted
5 Dec 2022
Amazing CV Research Day celebration @VUMC_heart with @alan_daugherty giving keynote address. Congrats @AzuahTheShort in @AmandaDoranLab for best student abstract. Record turnout to promote cardiovascular science @VUMCResearch.
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