CDH survival jumped 70% → 80% at Cincinnati Children's after protocol overhaul: gentler lungs, standardized care, earlier ECMO.
To hear Dr. Paul Kingma from Cincinnati Children's talk more on this, watch our video here:
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@CincyChildrens
ALT CDH survival had been stuck at 70% for two decades. After a protocol overhaul at Cincinnati Children's, where did it land? Take a guess: __%. Make your call, then swipe right. Logo of Cincinnati Children's at the top.
ALT Answer slide reading "After 20 years of stasis, Cincinnati Children's just broke the 70% wall." CDH survival went from 70% to 80%, a 10-point increase after two decades of no movement. Made possible by Cincinnati Children's, with their logo displayed. Includes a "Swipe right" arrow.
ALT Slide titled "What They Changed: A system-by-system overhaul, Aug 2023 to Spring 2024." Lists six protocol changes: ventilator peak pressure capped at 22, ECMO earlier initiation if needed, repair at 12-24 hours on ECMO or days 4-8 off, BP support with hydrocortisone for every baby, feeds with TPN until baby can feed by mouth, and sedation as a scheduled drip rather than PRN. Philosophy: "Protect the lungs. Everything else falls in line." Made possible by Cincinnati Children's, with their logo displayed.
ALT Slide titled "The Results" comparing 99 old-cohort babies vs. 36 new-cohort babies: survival went from 70% to 80%, median ventilator time dropped about 50% to 9 days, and ECMO survival went from 70% to 55%. ECMO use was essentially unchanged (41% to 45%), indicating the improvement was not driven by more ECMO. Made possible by Cincinnati Children's, with their logo displayed.