Can sirolimus eluting balloons redefine complex #PCI strategies? In this interview, @Simoneccles66 discusses with @gmcioffi about the evidence from the SELUTION DeNovo trial and the evolving role of drug-eluting balloons in complex coronary interventions. 🫀📈 #EuroPCR #interventionalcardiology

This article should be mandatory reading for every medical student, PhD candidate, researcher—and honestly, for anyone who mistakes expertise for certainty. “The importance of stupidity in scientific research” sounds provocative, almost offensive. But Martin Schwartz is not glorifying incompetence. He is describing the real operating system of discovery. Science is not built on knowing. Science is built on tolerating not knowing. That distinction matters. Most of education rewards correctness. School teaches us to answer. Exams reward speed, certainty, and precision. You feel intelligent when you get things right. Research is the opposite. Real research begins exactly where competence ends—at the frontier where nobody knows the answer, including the people you thought must know. That moment is psychologically brutal. You ask the expert. The expert shrugs. You assume you’re missing something. Then you realize: no—this is the work. You are not failing. You are standing at the actual boundary of knowledge. That feeling—“I must be stupid”—is often not a sign of inadequacy. It is often the first sign that you are finally asking an important question. Medicine struggles with this. We train doctors to avoid uncertainty, to fear being wrong, to perform confidence. But the best clinicians and the best scientists know how to sit inside ambiguity without collapsing into fake certainty. This is why AI in medicine also deserves caution. Systems trained only to reproduce established answers may become extraordinarily good at passing exams while being terrible at discovering what matters next. Guideline intelligence is not the same as scientific intelligence. Discovery requires productive stupidity: the willingness to stay with the uncomfortable, to look ignorant, to ask naïve questions, to be wrong repeatedly without protecting your ego. Most people want the authority of expertise. Very few want the humiliation required to earn it. But progress lives there. Not in certainty. Not in performance. Not in sounding smart. In the quiet discipline of saying: “I don’t know… yet.” And continuing anyway.

10/ My last and most important message It isn't just your hard work that built your interventional career- it's also the sacrifice, blood and sweat of those who love you

#ESCPrev2026 and what preventive conference is there without an exercise break!!! Packed venue - people exercising everywhere!!! @RitaPintoUL @EAPCPresident @fjpinto1960 @DrMarthaGulati @AnastasiaSMihai @gbiondizoccai @Hragy @MichaelPapadak2 @s_gati @KoKoMaung_ @purviparwani

May he rest in peace! 🙏🙏🙏

Why are we sending final-year Interventional Cardiology trainees back to the AMU? - CARDIOLOGY CONFIDENTIAL richardbogle.com/1/post/2026…

By far the best evidence for short term safety of DCB compared to DES in a real world setting imo, well done @CorballisTash and the team. @Simoneccles66 jacc.org/doi/10.1016/j.jcin.…

In 2 independent primary prevention cohorts, Lp(a) and IL-6 were independent predictors of #ASCVD risk, and their combination identified individuals at the highest risk. jacc.org/doi/10.1016/j.jacc.… #JACC #cvLipids

A perfect evening at Unawatuna, Sri Lanka!

How nice to see this! @Simoneccles66 @CorballisTash @vass_vassiliou @merinopoulos @tharushaguna4 @AlisdairRyding @ClintMaart @tomjohnson @DrPeterOKane @Ryvetsprog

👉Read online the design of the COPERNICAN trial 👉A potential paradigm shift in the treatment of myocardial infarction ❤️‍🩹 kwnsfk27.r.eu-west-1.awstrac… @sjorge4 @PCRonline @shci_sec @drassantos @EvaRumiz @GomezMenchero @GuillermoSchez @AntonelaLukicOt @EladioGalindo7 @hect2701

Beautiful Tangalle in Sri Lanka.

Ay-Young Her presenting JCR-DCB registry analysis of STEMI outcomes in DCB vs DES in STEMI showed better outcomes with DEB st 2 yrs. im sure that there are unmeasured confounders at play given even size- but i think it still is a viable strategy in selected pts. We need a dedicated RCT

Thank you Maldives!

#COMPLEXPCI2025 Imaging and IVUS-Guided Criteria for Optimal MSA to reduce 5 year MACE in dedicated 2-stent Left Main Bifurcation Stenting Distal LM MSA : 11.8 mm2 LAD Ostial MSA : 8.3mm2 LCX Ostial MSA : 5.7 mm2 #LMPCI #BifurcationPCI #ImageFirst #MSA @summitmd_cvrf #1/2

Great times @tct25 @sanfrancisco as faculty with @SimonEccleshall @brunoscheller @SanjogKalra @Jonathan Yap @Donna Lin, missed @aayshacader

I strongly believe that CBSL Governor Nandalal Weerasinghe and former Treasury Secretary Mahinda Siriwardena deserve the Sri Lankabhimanya award (the highest civilian award in Sri Lanka). It is because of the two of them as government employees that Sri Lanka is back to normal today. Dr Nandalal Weerasinghe shaped the monetary policy and Mahinda Siriwardena shaped the fiscal policy. Sri Lanka could have easily gone down the path of Lebanon or Venezuela with instability but as government servants, both of them did an outstanding job. Sri Lanka's economic recovery will be a case study for decades. The other reason I would like both Dr Nandalal Weerasinghe and Mahinda Siriwardena to get the Sri Lankabhimanya is the time they took over the positions of Central Bank Governor and Treasury Secretary respectively. It was a time of cause where things could have gone worse which could have risked their entire career reputation. But they took the risk, not for a small government salary they were to receive but for the country when it needed them the most. If President Anura Kumara Dissanayake can award these two outstanding Sri Lankans, Sri Lanka's highest civilian award, it would set a great example for all public sector workers and also encourage Sri Lankans in future to step up when the country needs them the most. They truly deserve it.

#Microplastics are increasingly detected in human tissues, with potential links to cognitive, cardiovascular, and inflammatory outcomes. 📌 Learn more in this JAMA Insights: ja.ma/3J8ZAXI

Beyond LDL: Residual inflammatory risk drives recurrent events post-AMI. Time to prioritize inflammation as a treatment target. jacc.org/doi/10.1016/j.jacc.… #cvAMI #Inflammation #JACC #cvLipids @DFCapodanno

Best places to travel in October, 2025. 1. 🇱🇰 Sri Lanka 2. 🇹🇷 Turkey 3. 🇺🇸 New Mexico 4. 🇪🇸 Valencia 5. 🇺🇸 New York City 6. 🇵🇭 Philippines 7. 🇧🇹 Bhutan 8. 🇧🇦 Bosnia and Herzegovina 9. 🇷🇴 Timisoara, Romania 10. 🇺🇸 San Francisco 11. 🇳🇦 Namibia (Timeout)