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Turlier lab @virtual_embryo

Modeling embryo & tissue morphogenesis combining physics and computer science @CbiToulouse

Joined May 2017
  • Tweets 193
  • Following 829
  • Followers 1,782
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Turlier lab@virtual_embryo
Apr 12
How can we learn tissue mechanics directly from patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5
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Very glad to see this great transatlantic collaborative work published in NCB 🎉! nature.com/articles/s41556-0… Congratulations to all authors: @Henry_de_belly, @andreu_gallen, Eric neiva, @OWeinerLab Funding from MSCA @EU_Commission & @CNRSbiologie

Long-range mutual activation establishes Rho and Rac polarity during cell migration

Nature Cell Biology - De Belly et al. show Rac induces membrane-tension-mediated mTORC2 activation to stimulate long-range Rho activation. Meanwhile, Rho-mediated contractility and blebbing at the...

nature.com
Henry De Belly@Henry_de_belly
Jun 10
Very excited to be sharing our new paper, just out in Nature Cell Biology! nature.com/articles/s41556-0… The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
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A true computational tour de force by Eric Neiva during his Marie Skłodowska-Curie postdoctoral fellowship in the team, now published in Journal Computational Physics: urlr.me/AuzK86 Congratulations, Eric! @CNRSbiologie Grateful to @EU_Commission for funding support
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How can we learn tissue mechanics directly from patterns and images? In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors. shorturl.at/PUzT0 1/5
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more replies
Beyond synthetic benchmarks, we show applications to mechanical parameter inference from microscopy images and to inverse design problems in epithelial tissues. 4/5
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We hope VertAX can help make inverse problems & differential programming more accessible in tissue mechanics. Thanks to @appasqui, @MaxenceErnoult, Italian colleagues, & other members of the team for this collaboration. Comments very welcome. Code github.com/VirtualEmbryo/Ver… 5/5

GitHub - VirtualEmbryo/VertAX: A differentiable JAX-based framework for vertex modeling and inverse...

A differentiable JAX-based framework for vertex modeling and inverse design of epithelial tissues - VirtualEmbryo/VertAX

github.com
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Turlier lab retweeted
Itai Yanai
@ItaiYanai
1 Nov 2024
If you think the next big idea in your field will come from inside the field, you're probably wrong.
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-01985-6

ALT https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-01985-6

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Conference Alert🚨 16-21 Feb 2025 From Soft Matter to Biophysics @ Les Houches FR t.ly/GXhPL Apply by Dec 15 to explore the latest in soft matter & biophysics, focusing on functional materials & synthetic biology! @karen_alim @Karin__Jacobs @MartinLenz @HerveTurlier
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Registrations are open for the Qlife Quantitative Biology spring school on Cell Dynamics in Developmental System March 3-April 04 2025. Great line of talks, lectures and hands-on practicals on omics, image analysis, modeling and inference: shorturl.at/Ygthh
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Team retreat in the Pyrenees 📝⛰️🍻
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Turlier lab retweeted
Henry De Belly@Henry_de_belly
3 Oct 2024
We recapitulate our findings in a mathematical model and show that this creates a feedback loop, where the front and back communicate through mechanical signals. @virtual_embryo @andreu_gallen It ensures that the cell can move forward in a coordinated way.
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Our workshop on Finite Elements for Cell & Tissue Morphogenesis at Villa Clythia @caescnrs was a great success ! Congratulations to @ericnumerics for the perfect organisation and looking forward to a next edition.
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Thanks to all speakers @MarinoArroyo2 @AnjaGeitmann @AlainGoriely Jessica Zhang @aland_lab @GabriellaBioMec Arezki Boudaoud Christophe Godin, Brendan Lane, Robert Nürnberg, Padmini Rangamani, Arnold Reusken, Axel Voigt, Sara Zahedi, Roman Vetter
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Our workshop on early embryo morphogenesis in Villefranche-sur-mer was a blast 💥 Thanks to all participants for the lively & friendly atmosphere, @RDumollard for co-organising and to @biodev_vlfr for the great welcome & fantastic setting. Looking forward to see you all again !
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@HerveTurlier @cavankatenaugh @CharrierLab @sneha_arao @LenartLab @Vane_barone @Chema_MD @sdebuyl @Alex_Mc_Dougall @HitoyoshiYasuo
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Turlier lab retweeted
kate cavanaugh@cavankatenaugh
7 Sep 2024
Some action shots from an amazing week in Villefranche-sur-mer. Thanks to @virtual_embryo and @RDumollard for pulling together some incredible minds (and microorganisms). Here is proof that there was actually some science happening!
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An interesting perspective article in Nature by @eisensteinium on the forces that sculpt embryos and how to measure them, highlighting our 3D tension inference method foambryo by @SachaIchbiah & @HerveTurlier nature.com/articles/d41586-0…

Push and pull: how to measure the forces that sculpt embryos

Nature - A steadily growing toolbox is giving researchers the ability to monitor and measure the physical forces that shape embryonic development.

nature.com
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A huge congratulations to @ap_pasqui for 1st prize in the @eelisa_eu student scientific competition in the Chemistry and bioengineering category. Well-deserved! More about the competition tinyurl.com/4uhfmf7a
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Great scientific discussions and insightful perspectives across biology & AI at the Fondation des Treilles, with wonderful colleagues @VirginieUhlmann @KrishnaswamyLab @MOSAICgroup1 @loicaroyer @ky396 @decbaycomp @will_prew @desi_ramram @martweig V. Vitelli, H. Isambert, C. He
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