Proteins biochemistry and structural biology. Head of the cryo-EM unit @bengurionu

Joined May 2016
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Nice ! Gating Mechanism of the Human Connexin 45 Gap Junction Channel biorxiv.org/content/10.64898…

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Officially out in Nature Communications: Structures of the most abundant AMPA receptor di-heteromer in the brain GluA1/A2 in the closed, open, and desensitized states! @shantigangwar @MariaKarela3 @LauraYen42 @MKCMU nature.com/articles/s41467-0…
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Recently honored to host the UK Ambassador to Israel, Simon Walters (@simonwaltersuk), at our lab at Ben-Gurion University ! 🇮🇱🇬🇧 We had an insightful discussion about the challenges of Alzheimer’s disease. Thank you for supporting scientific cooperation! @bengurionu @ukinisrael
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🚨 Happy to share our new preprint in which we explore different layers of the phage-bacteria arms race. The highlight: phage homing endonucleases attenuate bacterial defenses 🤯 A 🧵... (1/7) #bacteriology #antiphage #T6SS @TelAvivUni @TAUMedFaculty biorxiv.org/content/10.1101/…
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Very nice! Congrats @AlexanderSobol6 and team!
New online! Activation of kainate receptor GluK2–Neto2 complex bit.ly/3UGQsf5
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Very excited to share our latest study uncovering a functional cross-talk between BRD4 and MITF on chromatin in melanoma cells. A fantastic collaboration with @bernstein_lab, now published in NAR Cancer. 👉 academic.oup.com/narcancer/a…
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wow, congrats Ohad Medalia and team!
New online! The molecular basis of lamin-specific chromatin interactions bit.ly/4lb0NL4
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Pre-print out from the @SternbergLab with our contribution on the structural side. Great effort from Matt, Egill Tanner and the rest of the team leaded by awesome Sam! A 1 year effort on my side learning helical reconstruction by cryoEM... 👇
1/16 New pre-print from the Sternberg Lab! We uncover how temperate phages can use RNA-guided transcription factors to remodel the flagellar composition of their bacterial host and enhance their fitness. Find the preprint and full story here: tinyurl.com/mshwjd77
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Sweet!
25 Jul 2025
In the latest issue! The structure of human sweetness dlvr.it/TM6Tpg
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25 Jul 2025
🔥🔥🔥🧬 Excited to share our latest paper @NatureComms. A metabolic transport pathway that senses/synchs glucose Krebs cycle intermediates. rdcu.be/exMbS 🔬 🩺 #metabolism #diabetes #liver #bioenergetics . Kudos to Noa, Ahlam, Aharon & colleagues!
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A fun collaboration with Niv Papo and team! @bengurionu on nanobody interactions with PSMA as a prostate cancer targeting approach, below two nanobodies bound to the same target! sciencedirect.com/science/ar…
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1 Jul 2025
New study shows how bacteria evolved powered-up propellers imperial.ac.uk/news/265473/n… ... nature.com/articles/s41564-0…
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Thrilled to share our latest work, just published in Redox Biology!
We show that Cdc48 functions as a redox-sensitive thiol switch regulating proteostasis during stationary phase in yeast.
 sciencedirect.com/science/ar…

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