Beautiful work Shiraishi et al! They show that alveolar cells plated on 10 um upatterns don't spread and retain their AT2 differentiation, unlike cells plated on larger upatterns. Actin accumulation around the nucleus and yap/taz localization also depend on upattern size🤩
Now online! Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate
dlvr.it/SkWh2y