@AkbarianLab profile picture
AkbarianLab @AkbarianLab

exploring epigenetic regulation of gene expression to identify drug targets and novel treatment avenues for psychiatric disease @sinaibrain @icahnmountsinai

Joined September 2021
  • Tweets 53
  • Following 131
  • Followers 349
7 Photos and videos
AkbarianLab retweeted
Dr. Jennifer Blaze@jblaze8911
3 Sep 2024
After over 8 years at @IcahnMountSinai from postdoc to instructor to research assistant professor in @AkbarianLab I will be joining a biotech startup in NYC in a few weeks. Leaving academia was a difficult decision, and I have a lot of mixed feelings about this career change 1/3
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Last day in the Akbarian lab for @TovaLambert8 , the baking, 10x and FACS expert, organizing extraordinaire! We will miss her (and according to her amazing cake, she will miss us too)! Best of luck to Tova as she begins her PhD at @EinsteinMed
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AkbarianLab retweeted
Neuropsychopharmacology@npp_journal
16 Feb 2024
#ThisWeekInNPP Work from @jblaze8911 @JDCalebBrowne @EricJNestler @AkbarianLab & @VannaZachariou shows that dynamic regulation of tRNA cytosine methylation is associated with opioid reward processing in the medial prefrontal cortex of rodents nature.com/articles/s41386-0…

tRNA epitranscriptomic alterations associated with opioid-induced reward-seeking and long-term...

Neuropsychopharmacology - tRNA epitranscriptomic alterations associated with opioid-induced reward-seeking and long-term opioid withdrawal in male mice

nature.com
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Check out the new publication from @jblaze8911 and @JDCalebBrowne showing the importance of the tRNA epitranscriptome in opioid addiction!
Dr. Jennifer Blaze@jblaze8911
12 Feb 2024
We're so proud of the team effort that went into this one! Check out our recent publication in @npp_journal linking tRNA epitranscriptomics with opioid use @JDCalebBrowne @EricJNestler @AkbarianLab @VannaZachariou nature.com/articles/s41386-0…
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AkbarianLab retweeted
Sergio Espeso-Gil@SergioEspesoGil
22 Jan 2024
#Researchpaper out! Pyramidal neurons are one of the most relevant brain cells. While firing, a protein called #SATB2 is involved into forming intriguing nuclear invaginations acting as key regulator inducing #3Dgenome changes modulating #cognition genes. tinyurl.com/r85ucavk
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Congratulations to @WahlNi @SergioEspesoGil and all co-authors on this collaborative work recently published in @MolecularCell !!!
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We're so thrilled to see @_alicekmin_ amazing work on a humanized mouse model of neuroHIV as the top featured story on the monthly HIV News from NIDA letter! @taliaswartz @JVirology
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AkbarianLab retweeted
Dr. Jennifer Blaze@jblaze8911
7 Dec 2023
My second @ACNPorg meeting was such a fun week of science, friends, and some sunny adventures in Tampa! Great to catch up with friends and colleagues, and get some great mentorship from my science heroes! #ACNP2023
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Excited to present our new publication in @JVirology and honored to be the Editor's pick! Led by the talented @_alicekmin_ we show a new humanized mouse model of neuroHIV through very collaborative effort between our lab, @taliaswartz and Ben Chen labs. journals.asm.org/doi/epub/10…
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AkbarianLab retweeted
Ataxia Global Initiative@ataxia_global
19 Oct 2023
Mount Sinai Hospital @AkbarianLab and UCLA @GeschwindLab are seeking postmortem brain tissue from patients with FGF14-GAA / SCA27B, RFC1 disease / CANVAS and FA (motor cortex and/or cerebellum). Contact: sathiji@gmail.com Thank you!
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It's great to see work from our lab and @kristenbrennand featured on the cover of @molpsychiatry this month! nature.com/mp/volumes/28/iss…

Molecular Psychiatry - Volume 28 Issue 5, May 2023

Confocal images of iDOPA neurons with dopaminergic neuron markers. For more information see the article by Powell et al. on pages 1970–1982.

nature.com
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As we recognize #FBIat15, read how our @SinaiBrain scientists contributed to technologies responsible for the current renaissance in neuroscience in our Specialty Report: mshs.co/3PGbS95 @panos_roussos @towfiqueRaj @mazelab @AkbarianLab
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Our study on single nucleus transcriptomic profiles from midbrain of subjects with opioid use disorder is now online at @NatureComms!   nature.com/articles/s41467-0…

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A productive collaboration with our colleagues at Wayne State University (Detroit) and NSU Florida (Miami), with a total of 95 postmortem brain samples included, making it to date one of the largest studies in this field.
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Check out this new Akbarian lab preprint!
Dr. Jennifer Blaze@jblaze8911
8 Sep 2023
A new Blaze Browne et al. preprint showing the novel link between tRNA methylation and opioid addiction/withdrawal! @JDCalebBrowne @EricJNestler @AkbarianLab @VannaZachariou biorxiv.org/content/10.1101/…
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We're so thrilled for @_alicekmin_ !!!
Talia H. Swartz@taliaswartz
28 Jul 2023
So excited and proud of @_alicekmin_ #mdphd, who got an amazing score (2%ile) on her #K08 submission and faculty appointment after #IDfellowship. #PhysicianScientist @IcahnMountSinai Thanks to the amazing collaboration with @AkbarianLab and @benkchen 🥳 @DOMSinaiNYC
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Two new preprints from the lab are out now! Both from our longstanding collaboration with @kristenbrennand lab, we explore 1) R loops in the developing brain and 2) chromosomal conformations in schizophrenia risk loci biorxiv.org/content/10.1101/… biorxiv.org/content/10.1101/…

R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type...

Here, we construct genome-scale maps for R-loops, three-stranded nucleic acid structures comprised of a DNA/RNA hybrid and a displaced single strand of DNA, in the proliferative and differentiated...

biorxiv.org
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A great first poster presentation from our talented associate researcher @TovaLambert8 !!!
Tova Lambert@TovaLambert8
16 May 2023
Presented my first poster today at 2023 NIDA Genetics & Epigenetics Meeting! Abstract on NIH website @ nida.nih.gov/sites/default/f…
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The Akbarian lab is sad to say goodbye to our amazing research associate @ValadaAditi who has been vital to implementing protocols like 10x single cell transcriptomics over the past two years... To celebrate her last day, @tovalambert8 crafted a gorgeous @10xgenomics cake!
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@10xGenomics
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Aditi will be attending medical school in July and starting a promising career as an MD! Best of luck from all of us in the lab!
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