Joined January 2019
- Tweets 99
- Following 504
- Followers 416
- Likes 641
12 Photos and videos
Pinned Tweet
29 Mar 2024
Check out our study linking T cell signatures with allo-HCT outcome in AML patients out in @BloodJournal🩸
Big thanks to everyone involved, especially to @muedequadrat and my PhD supervisors @zauggj @EMBL & C.Pabst @uniklinik_hd @MMPU_Heidelberg. 🧵(1/11)
ashpublications.org/blood/ar…
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Tissue organization is fundamental to how tissues function - yet in cancer such spatial patterns can progressively break down. Ever wondered how?!
Check out our new study, where we investigate how lymphoma reshapes lymph node architecture 👀
A new study maps the organisation of immune & stromal cells in lymph nodes and shows its association with prognosis in certain lymphomas.
This has implications for long-term prognosis in cancer patients & can potentially open up new therapeutic avenues.
embl.org/news/science-techno…
ALT Reactive lymph nodes, as visualised using multiplexed immunofluorescence. B-Cells are shown in red (PAX5), T-cells in blue (CD3), lymphatic endothelial cells and fibroblastic reticular cells in green (PDPN), and follicular dendritic cells in cyan (CD21). Credit: Felix Czernilofsky
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Anna Mathioudaki retweeted
17 Sep 2025
How much does your medical history reveal about your future?
As a team effort of @MoritzGerstung and @ewanbirney's labs, we present Delphi-2M, a transformer for modelling future health based on past medical history.
nature.com/articles/s41586-0…
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18 Mar 2025
A must-read (& must-use) if you work with spatial transcriptomics data! 🍳
Having used Segger myself on Xenium data from multiple tissues, I can say the transcriptome profiles are so much cleaner-a game changer🤩
Congrats @HeidariElyas!
18 Mar 2025
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New preprint out! 🍳
Our team at @EMBL, @DKFZ, and @MSKCancerCenter built #segger—a fast, accurate cell segmentation tool for ST. It’s a transcript-to-cell link predictor that matches transcripts to their cell origins in a snap!
ALT segger's logo.
ALT segger's network architecture.
ALT Message passing intuition behind segger’s link-prediction model.
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Anna Mathioudaki retweeted
5 Feb 2025
New pre-print from Thomas Höfer, Daniel Hübschmann, @haas_lab and myself, with first authors @Esther_RCorrea @FloGrunschlager and Tamar Nizharadze doi.org/10.1101/2025.02.04.6… @DKFZ @NCT_HD @ChariteBerlin @hi_stem_lab BIH & MDC 1/7
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Anna Mathioudaki retweeted
15 Dec 2024
Finally #PhDone 🎓🎊
Big thanks to my supervisors @sahm_lab @MoritzGerstung the best lab mates 🥹❤️
#PhDatDKFZ @DKFZ @uniklinik_hd
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Anna Mathioudaki retweeted
19 Sep 2024
Excited to share our first preprint with @zauggj @embl! We screened 1,296 transcription factors for repressors that block unwanted plasticity and found many putative tumour suppressors. PROX1 stands out as hepatocyte safeguard that prevents #livercancer. biorxiv.org/content/10.1101/…
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Anna Mathioudaki retweeted
12 Sep 2024
🚀 Big news! Prof. Dr. Judith Zaugg @zauggj will lead the 'Molecular and Computational Hematology-Immunology' group at @DepBiomedicine. Her research focuses on the molecular mechanisms behind diseases of the blood and immune system, using cutting-edge single-cell and computational techniques. biomedizin.unibas.ch/en/comm…
#Welcome2024 #welcometotheteam #MolecularMedicine #Hematology #Immunology #TeamDBM
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Anna Mathioudaki retweeted
23 May 2024
My former student @alex_w_jung used detailed health data from 6.7 million Danes to learn risk models for 20 cancer types.
A massive data crunch of 60 million hospital visits, 90M diagnoses, and a total of 193M life-years between 1978 and 2018.
thelancet.com/journals/landi…
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21 May 2024
Check this out 🤯
1 mouse - hundreds of cancer clones & genotypes
1 readout - simultaneous genotype & phenotype information
Talk about efficiency hm 😁 congrats to everyone!
21 May 2024
0/ Preprint alert! 🚨
One step closer to solving the genotype ➡ phenotype puzzle in cancer! Led by @BreinigMarco, @LomakinAI, and @HeidariElyas, our novel approach, #CHOCOLAT_G2P 🍫, deciphers the impact of combinatorial alterations on tumor phenotypes and their environment.
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Anna Mathioudaki retweeted
6 May 2024
Excited to share the first spatially resolved multiomics atlas for human bone marrow, published today in @CellCellPress. twtr.to/cJ099. Wonderful collaborations with Ling Qin @LingQin6, Charles Nelson, Martin Carroll, Ivan Maillard, Vinohd Pillai @pillai_vinodh labs!
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Anna Mathioudaki retweeted
21 Apr 2024
The @MoritzGerstung lab @DKFZ was on a retreat in the picturesque village of Reipertswiller this week.
Lots of great brainstorming, new ideas, career advice and hiking ⛰️🥾
Watch out for all the cool science this year! 🧬🔬🗺️🤖👀
#CancerResearch #AI
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11 Apr 2024
Constantly amazed by how much one can recover from just H&E tissue stains!
Case in point: predicting PDL1 expression from H&E of solid tumors using deep learning 🔬
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29 Mar 2024
Check out our study linking T cell signatures with allo-HCT outcome in AML patients out in @BloodJournal🩸
Big thanks to everyone involved, especially to @muedequadrat and my PhD supervisors @zauggj @EMBL & C.Pabst @uniklinik_hd @MMPU_Heidelberg. 🧵(1/11)
ashpublications.org/blood/ar…
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29 Mar 2024
💡Our study allowed to delineate compositional, transcriptional and functional characteristics of T cells associated with allo-HCT outcome. We establish GPR56 on CD8 T cells as a hallmark of allo-transplantation, suggesting it as a dynamic marker for antigen-experience. (10/11)
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29 Mar 2024
So much more to come!
For now - explore our scRNA-seq data and our gene regulatory networks here: apps.embl.de/allosct/ And feel free to reach out for more details!
Thanks to all our collaborators @AryanKamal_ @LabTidow and everyone else!
(11/11)
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