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Arlotta Lab @ArlottaLab
Joined January 2018
  • Tweets 358
  • Following 329
  • Followers 5,897
31 Photos and videos
Thanks to Carl Zimmer for highlighting some of the lab's work using organoids as a tool for modeling brain development and disease! nytimes.com/2025/11/06/scien…

What We Can Learn From Brain Organoids

Lab-grown “reductionist replicas” of the human brain are helping scientists understand fetal development and cognitive disorders, including autism. But ethical questions loom.

nytimes.com
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📢 📢Delighted to announce our latest pre-print co-led by our fantastic and talented postdocs @IreneFaravelli and @bolanosAnton 👩🏻‍🔬👩🏼‍🔬💪! Human cortical organoids record developmental time for 5 years in vitro. 🧫🧠⏳. A huge collaborative effort, big thanks to all co-authors! 🧵👇
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🙏 This has been a fantastic collaborative experience! Huge thanks to our coauthors and collaborators! @AnqiWei2023 @tylerfaits @AbhiSampKumar, Sophia Andreadis @RKastli @MMonteroCrespo @mc_steiger @LeibleDaniel Elizabeth Zhang, Bobae An, @YaronMeirovitch @Sayarasilwal
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@SungMin_Yang00, Alexander Kovacsovics, @XAdiconis @Helenekretzmer @jzlevin @eboyden3 Jeff Lichtman @avivregev and Alexander Meissner @HSCRB @harvardstemcell @Harvard @harvardbrainsci @broadinstitute @StanleyCenter @EMBO
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Congratulations to @Andrew_C_Payne, @SGRodriques & @eboyden3 for their beautiful new preprint on the PRISM method! This study combines protein barcodes for self-correcting neuron tracing with nanoscale molecular context. Exciting work led by Sung Yun Park and Arlo Sheridan!
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biorxiv.org/content/10.1101/…

Combinatorial protein barcodes enable self-correcting neuron tracing with nanoscale molecular...

Mapping nanoscale neuronal morphology with molecular annotations is critical for understanding healthy and dysfunctional brain circuits. Current methods are constrained by image segmentation errors...

biorxiv.org
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Congratulations to Paola for being elected to the National Academy of Sciences! nasonline.org/news/2025-nas-…

National Academy of Sciences Elects Members and International Members - NAS

WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original...

nasonline.org
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Big congratulations to Paola for winning this year's ISSCR Momentum Award!!! isscr.org/isscr-news/paola-a…
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Massive congratulations to Paola Arlotta for her election to the National Academy of Medicine today!!! nam.edu/national-academy-of-…

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Arlotta Lab retweeted
HSCRB@HSCRB
3 Jul 2024
A revolutionary new platform, relying on what researchers in the @ArlottaLab are calling ‘brain chimeroids’, offers a unique opportunity to understand how the human brain reacts to various stimuli. hscrb.harvard.edu/news/brain…
Slide depicting a composition of six multicolor brain chimeroids

ALT Slide depicting a composition of six multicolor brain chimeroids

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Kudos to @LodatoS_Lab that took the stage today at #FENSForum2024 at the #EJN special lecture to speak about spontaneous activity and the development of the cerebral cortex. 👩🏼‍🔬🧠🔬#alumni #neuroscience #womanInStem
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Thank you so much @BhaduriLab! We are thrilled to see our work on Chimeroids highlighted in your News and Views article in @NatureNV. Your summary truly captures the essence and significance of our research. #Science #Neuroscience #Brain #Organoids 👉nature.com/articles/d41586-0…

Chimeric brain organoids capture human genetic diversity

Nature - Cortical organoids made from a mix of stem cells from different donors.

nature.com
Aparna Bhaduri@BhaduriLab
26 Jun 2024
Congratulations to @BolanosAnton @IreneFaravelli @ArlottaLab on their paper about chimeroids! Honored to have written a News and Views @NatureNV summarizing the paper and its significance, which can be found here: springernature.com/gp/resear…
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Arlotta Lab retweeted
Waggoner Lab@LabWaggoner
27 Jun 2024
Chimeric brain organoids made by combining cells from up to five donors capture human genetic diversity Commentary @Nature @BhaduriLab nature.com/articles/d41586-0… @ArlottaLab @BolanosAnton @IreneFaravelliic nature.com/articles/s41586-0…
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Today @IreneFaravelli and @BolanosAnton are presenting their beautiful work about #Chimeroids and long-term #organoids at #FENS2024. Don’t miss it! #Neuroscience #StemCells #Innovation
Arlotta Lab@ArlottaLab
25 Jun 2024
Are you at #FENS2024? Don’t miss our posters from @BolanosAnton and @IreneFaravelli on Thursday morning. Join us for insightful discussions and innovative research utilizing #BrainOrganoids! See you there! 🧠🧫✨ #Neuroscience #PosterSession PS03-27AM-292 - PS03-27AM-287.
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Arlotta Lab retweeted
Daniela Di Bella@DanielaJDiBella
27 Jun 2024
Very happy to see this one out! Congrats to all authors 🎉🎉
Arlotta Lab@ArlottaLab
26 Jun 2024
Finally out @Nature! “Chimeroids” as powerful avatars of the human Brain can recapitulate unique features and responses of individual people. Congrats to our outstanding co-leads @BolanosAnton, @IreneFaravelli👩‍🔬👩‍🔬and all the team!🧫🧠 nature.com/articles/s41586-0…
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Arlotta Lab retweeted
Abhishek Sampath Kumar@AbhiSampKumar
26 Jun 2024
In the multi-donor brain chimeroids, we also show that the different donor lines are spatially distributed, profiled with Curioseeker @curiobio . Excited to have contributed to this tremendous work led by @BolanosAnton @IreneFaravelli @ArlottaLab. Congratulations to all authors.
Noelia Antón-Bolaños@BolanosAnton
26 Jun 2024
📢Thrilled! My 1st piece of work of my postdoc at @Arlottalab is out @Nature! This has been a huge co-lead effort with @IreneFaravelli👩‍🔬👩‍🔬🤩 Link: nature.com/articles/s41586-0… Tweetorial 👇🧵
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