Psychiatry resident @CUAnschutz 🏔️ | 🧠 🧬 🔬 | MD, PhD @columbia 🌃
Joined February 2019
- Tweets 351
- Following 270
- Followers 219
- Likes 575
26 Photos and videos
Pinned Tweet
19 Mar 2023
Beyond thrilled to have matched into the Research Track Psychiatry residency @CUAnschutz!!
Huge thanks to @psimslab @david_sulzer and so many others for an amazing 8 years in NYC...
I can't wait to be back home in CO and get to work @CU_Psychiatry! 🏔️🌄
#Match2023 #psychmatch
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📣 New today!
📄Genome-wide prediction of dominant and recessive neurodevelopmental disorder-associated genes
🧑🤝🧑@RyanDhindsa @awzoghbi & colleagues
cell.com/ajhg/abstract/S0002…
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Ben Hobson retweeted
6 Feb 2025
200 retweets and I’ll do the 200/400 double at worlds…. I’ll beat Noah and Vernon 😂🤝🏾… Grant also gotta see me in the 110 too.. I’ll take the stripes off his lil vest
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Ben Hobson retweeted
6 Dec 2024
Hello world! After my lab has been operating in "stealth mode" for 1.5 years, I am excited to announce that we finally have a website: huttenhainlab.com
By the way I'm also hiring and looking for a postdoc with proteomics experience: postdocs.stanford.edu/prospe…
#TeamMassSpec
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Ben Hobson retweeted
23 Nov 2024
Electrical synapse molecular diversity revealed by proximity-based proteomic discovery biorxiv.org/cgi/content/shor… #biorxiv_neursci
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Ben Hobson retweeted
17 Jul 2024
And we are LIVE! @sthom003 and I finally have our lab website. Check out the Laboratory of Translational Psychiatry and all the great work by our team. 🧠Research, Training and Community. Thanks to @stellatecomms for their ingenuity on this. balethompsonltp.org
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Ben Hobson retweeted
2 Jul 2024
Thrilled to see our paper "A Proximity Proteomics Pipeline with Improved Reproducibility and Throughput" published! It describes the automated enrichment of biotinylated proteins in a 96-well plate format for spatial proteomics and protein interactions.
embopress.org/doi/full/10.10…
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19 Apr 2024
Beautiful work… This study is so exciting! Among many exciting findings, the authors found ultrastructural evidence for localization of TRiC/CCT in DA axons and the lack of axonal ribosomes in DA neurons, corroborating in vivo results from my graduate studies
16 Apr 2024
Extremely happy to share our preprint on the Ultrastructural Dynamics of Dopaminergic Presynaptic Release Sites revealed by CryoCLEM. A pleasure working with good friends and colleagues on this! @LycasEats @DustinMorado @UlrikGether @BriggsGroup
biorxiv.org/content/10.1101/…
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Ben Hobson retweeted
25 Mar 2024
So excited to see our work on "Profiling the proximal proteome of the activated μ-opioid receptor" using APEX-based proximity labeling and quantitative mass spec published today. It is the result of an amazing team effort!
nature.com/articles/s41589-0…
#TeamMassSpec #Proteomics #GPCR
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Ben Hobson retweeted
20 Dec 2023
Massive 10 year effort in lab spearheaded by @leonardoaparrar and Kayal (secret account 🤔). Unreal cover by @EmmaVIDALL that says it all.
20 Dec 2023
2023's final issue is out! cell.com/neuron/current
Cover story is from @Roy_Lab_Thinks's lab revealing an unexpected physiologic role for α-synuclein phosphorylation in clustering synaptic vesicles and restricting neurotransmitter release. Read it here cell.com/neuron/fulltext/S08…
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27 Jul 2023
Nat Biotech recently published a provocative study claiming single synapse RNA-seq. Unfortunately, there is no evidence demonstrating droplet-based sequencing of single synaptosomes. They are likely studying random pieces of cellular debris. Our reply:
nature.com/articles/s41587-0…
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Ben Hobson retweeted
26 Jun 2023
We’re THRILLED to have this paper out - exploring how BAMs promote neuroinflammation in a model of PD. Congrats to @amschonhoff and huge thanks to @ASAP_Research @MichaelJFoxOrg @uabmedicine @uab_neurology and the rest of the Harms lab!! nature.com/articles/s41467-0…
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Ben Hobson retweeted
16 Apr 2023
Proximity labeling is a powerful proteomics approach to map cellular organization of proteins and their interactions, but the multistep sample preparation has restricted scalability. Our new preprint offers a solution: biorxiv.org/content/10.1101/…
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Ben Hobson retweeted
27 Mar 2023
If you wish to know how a scientist gets trapped between arts and science you might want to give this piece a chance!😂🐘🐘🐘🧠🧠🧠🎶🎹🪕🎻
David Sulzer’s Wild World of Music | The New Yorker newyorker.com/magazine/2023/…
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Ben Hobson retweeted
24 Feb 2023
How can we kill chemo-resistant glioma cells? Turns out they are uniquely vulnerable to #ferroptosis. Awesome collaboration with @CUBrainTumorLab @MateiBanu combining a new mouse glioma model with human glioma slice culture/scRNA-seq: biorxiv.org/content/10.1101/…
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11 Feb 2023
If you thought ATAC was cool, wait til you see DEFND-seq!🛡️🧬🔥
Single-nucleus combined RNA/DNA-seq using the 10x Multiome kit!
Amazing work from @olsen_timr
10 Feb 2023
Happy to share an approach to high-throughput, joint single-nucleus RNA/DNA-seq. Basically: prep nuclei for snATAC-seq badly on purpose and feed to the 10x Multiome kit for RNA/ATAC. Gives high-complexity RNA/DNA libraries instead. Hat-tip @olsen_timr: biorxiv.org/content/10.1101/…
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2 Dec 2022
This is a great collection of reviews on the immune system in PD, including from @arlehamn @SetteLab and many others! @david_sulzer and I wrote about neuronal antigen presentation: content.iospress.com/article…
1 Dec 2022
Growing evidence for the role of the immune system in PD: Experts review the latest evidence for the link between immune activation and neuroinflammation and PD in this new supplement issue: tinyurl.com/PDimmunesystem. #parkinsons #immunesystem @basbloem @kalialabs
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Ben Hobson retweeted
7 Nov 2022
Folks- I have a preprint update on our #dopamine quest:
"Cholinergic Interneurons Drive Motivation by Promoting Dopamine Release in the Nucleus Accumbens". I will try to summarize it here:
biorxiv.org/content/10.1101/… 1/9
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Ben Hobson retweeted
12 Oct 2022
Excited to share new work that truly spanned bench (computer) to bedside a thread 🧵(1/n) alz-journals.onlinelibrary.w…
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