Translational Brain Tumor Research Laboratory @ Columbia University Irving Medical Center | Led by Peter Canoll MD, PhD and Jeffrey N. Bruce MD

Joined February 2023
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Columbia Translational Brain Tumor Laboratory retweeted
Dr. @ninayoh won the @ConquerCancerFd Young Investigator Award for her research on Focused Ultrasound to open the Blood-Brain Barrier for liquid biopsy in children w/ Progressive DMG, potentially revolutionizing pediatric #braintumor treatment. 👏 Read 👉ow.ly/E04L50OIz3s
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Columbia Translational Brain Tumor Laboratory retweeted
Congratulations to Dr. @ninayoh, on receiving the 2023 @ConquerCancerFd – The Sontag Foundation Young Investigator Award! 🏆🔬 Study Title: "Using Focused Ultrasound to Open the Blood-Brain Barrier for Liquid Biopsy; A Study in Children with Progressive Diffuse Midline #Glioma"
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Excellent work from @ODalahmah & @MikeArgenziano & Adithya Kannan et al just published in @NatureComms !
Excited to share our new paper now out at @NatureComms, led by @ODalahmah & @PCanoll, where we take a multi-omics approach to uncover new therapeutic targets for the #GBM microenvironment through the lens of cellular composition. 1/3 nature.com/articles/s41467-0…
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Columbia Translational Brain Tumor Laboratory retweeted
Check out our team's highlights from #AANS2023 neurosurgery.columbia.edu/ne…
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Columbia Translational Brain Tumor Laboratory retweeted
26 Apr 2023
26 Apr 2023
Convection-Enhanced Delivery Of Immunomodulatory Therapy For High-Grade #Glioma. academic.oup.com/noa/advance… #btsm @NeuroOnc
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Huge congratulations to Bruce/Canoll lab member, @ColumbiaPS student, and incoming @ColumbiaNeuro resident @MikeArgenziano for winning the Gladiator Project award at the #AANS2023 annual meeting, presenting our unique clinical trial for local drug delivery in #glioblastoma
22 Apr 2023
Celebrating the @TumorSection awardees for the year! #AANS2023 #neurosurgery
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Learn more about our clinical trial, published in @TheLancetOncol , below: thelancet.com/pdfs/journals/…

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Columbia Translational Brain Tumor Laboratory retweeted
22 Apr 2023
Outstanding talk by ⁦@MikeArgenziano⁩ at #AANS2023 presenting our work on #GBM and #ferroptosis demonstrating how we can target resistant cancer cells. Learning from clinical trials to advance therapy! So proud of Michael, physician scientist superstar!
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Huge congratulations to all of the Bruce-Canoll lab medical students (Colin, Adi, Cole, and Will) who presented their research at @ColumbiaPS Student Research Day today! Amazing work! 👏
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Columbia Translational Brain Tumor Laboratory retweeted
A form of cell death discovered 10 years ago at Columbia could help scientists design better, more targeted therapeutics to treat illnesses like cancer, write Professors @BStockwell and Wei Min in a new paper. bit.ly/3JNLIQz
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Columbia Translational Brain Tumor Laboratory retweeted
19 Mar 2023
Epic #Match2023 for Sims lab MD/PhD alums with @BenHobs3 returning to his home state for psychiatry @CUAnshutz and Jordan Metz staying in his home state @ColumbiaPath. Couldn't be more proud! Can't wait to see what they do next.
19 Mar 2023
Beyond thrilled to have matched into the Research Track Psychiatry residency @CUAnschutz!! Huge thanks to @psimslab @david_sulzer and so many others for an amazing 8 years in NYC... I can't wait to be back home in CO and get to work @CU_Psychiatry! 🏔️🌄 #Match2023 #psychmatch
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Columbia Translational Brain Tumor Laboratory retweeted
Congratulations to our 2023 Columbia Neurosurgery matches! Michael G. Argenziano, MS, MD, Adrian Jimenez MD, and Amitra K. Singh, MD!
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Columbia Translational Brain Tumor Laboratory retweeted
Excited to share my thoughts on our new paper in @NatureComms with Peter Canoll, Jeff Bruce, Simon Cheng and our lab members on a #precision #diet that promotes #ferroptosis in #brain #cancer @columbia @Columbia_Bio medium.com/@brentstockwell/a…
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Huge thank you to the @Lancet for visiting our lab and giving us the opportunity to showcase some of our current work tackling glioma heterogeneity via ferroptosis! @PCanoll @MateiBanu @MikeArgenziano @psimslab
We hosted The Lancet last week- read the full day's program here: neurosurgery.columbia.edu/ne…
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Columbia Translational Brain Tumor Laboratory retweeted
24 Feb 2023
How can we kill chemo-resistant glioma cells? Turns out they are uniquely vulnerable to #ferroptosis. Awesome collaboration with @CUBrainTumorLab @MateiBanu combining a new mouse glioma model with human glioma slice culture/scRNA-seq: biorxiv.org/content/10.1101/…
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Check out our new preprint! A study led by @MateiBanu, PGY7 @ColumbiaNeuro. We find that astrocytic-like quiescent #glioma cells are driven by distinct metabolic programs, and this treatment-resistant glioma subpop can be effectively targeted via #ferroptosis in human GBM tissue.
A cell state specific metabolic vulnerability to GPX4-dependent ferroptosis in glioblastoma biorxiv.org/cgi/content/shor… #bioRxiv
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Congrats and thank you to all involved in this huge translational study! @PCanoll, @psimslab, @MikeArgenziano, Thanassis Dovas, Wenting Zhao, @bstockwell, Jeffrey Bruce @ColumbiaNeuro
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