Will we be living to 150? Here's my conversation with Peter Diamandis (@PeterDiamandis), Exec. Chairman @XPRIZE @fountainlife_hq (and others) (0:00) – Intro: Are we going fast enough to reach longevity escape velocity? (3:00) – AI, digital superintelligence, and modeling human biology (6:00) – Why billionaires hesitate to fund longevity—and why that needs to change (10:00) – Abundance, healthspan, and shifting the mindset of what’s possible (14:00) – Why the next 5-8 years will be turbulent—and the light ahead (18:00) – Purpose, not passion: building your own mission for the future (21:00) – Universe 25, social collapse, and the need for challenge (25:00) – “Don’t Die” vs. living a purpose-driven life (28:00) – Scaling healthspan and solving fiscal crises through wellbeing (31:00) – How to access wisdom in an age of overwhelm (33:00) – Ray Kurzweil, meta-trends, and the century of progress in one decade

David Sinclair is on a mission to turn age reversal into a $100 pill. Right now, his gene therapy costs roughly $10 million to manufacture and requires a direct injection into whichever organ you're targeting. That's not going to work for 8 billion people. So Sinclair's team made a breakthrough. They found that the three age-reversal genes aren't the only path to resetting cells. They discovered CHEMICALS that do the same thing. In mice, they can now give an animal a liquid - not genes, not injections, a drink - and rejuvenate tissues in 4 weeks. Sinclair says it's now normal for his students to casually report: "We just rejuvenated the ear. We just rejuvenated the skin. We just cured ALS (motoneuron disease) in these animals." He calls his lab "Willy Wonka's chocolate factory" because the discoveries blow him away every week. But he wants one molecule that does everything. So they used AI to screen 8 BILLION candidates. They're now down to three molecules that work. And they're using AI to try to combine all three into one. The gene therapy could cost over $100,000 per treatment. Sinclair's goal: "What if it could be $100 instead? That's what I'm working for. I want to democratize this technology so anyone even in Kenya can take these medicines." They should know within a year or two if the molecules work in mice. The gene therapy is the proof of concept. The pill is the endgame. David Sinclair is speaking on May 6th at SynBioBeta this year - discussing the science of slowing and reversing aging. If longevity is the world you're in, the investors, partners, and scientists who matter in this space will be in the room. Link for tickets below. — @davidasinclair