Interdisciplinary team seeking to understand how proteins regulate mitochondrial homeostasis in healthy and diseased cells

Joined February 2020
22 Photos and videos
Blake Hill Lab retweeted
Image.sc LIVE around the world! Jan 18(Euro, Africa, America) -19(Asia, Aus, NZ). You can chat directly with bioimage analysis experts in your time zone! Post your question ideally before Jan 11, and they will match you with the best person. forum.image.sc/t/image-sc-li…
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Blake Hill Lab retweeted
New in JBC press: "Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission." Learn more: jbc.org/article/S0021-9258(2…
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Blake Hill Lab retweeted
Pleased to announce that my PhD thesis work in @Blake_Hill_Lab on structural mechanisms governing vertebrate FIS1 function is finally out in JBC. sciencedirect.com/science/ar… 🧵a thread

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These results suggest reciprocal interactions between the Fis1 arm and conserved surface are important for Drp1 recruitment and mitochondrial fission. (9/10)
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Ultimately, our data support a direct Fis1-Drp1 interaction, in which the Fis1 arm may (via a kinetic effect) occlude the binding site. This interaction promotes mitochondrial fission and suggests the yeast and human proteins are more similar than previously thought. (10/10)
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Blake Hill Lab retweeted
I'm now officially hooked on #LLMs for #BioImageAnalysis presuming they will do my job one day. Welcome BIA-Bob! 🔬🖥️🤖 github.com/haesleinhuepf/bia…
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Blake Hill Lab retweeted
Set of #mitochondria now united with their owner Dr @kanolden. Cherry, oak, walnut and padauk woods.
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Blake Hill Lab retweeted
Its official (as of a week ago)! So thankful for my experiences in the @Blake_Hill_Lab the last several years and for having @_Blake_Hill as a mentor #PhinisheD #MCWMSTP
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Congrats to Dr. Kelsey Nolden on the successful completion of her PhD!! Now time for the celebration!
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Blake Hill Lab retweeted
Defending my PhD dissertation tomorrow! DM for Zoom info if interested in attending virtually.
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Blake Hill Lab retweeted
Had such a great week at @StJudeResearch learning about their facilities, programs, and ongoing research as well as sharing some of our lab's own research! #StJudeNGSS
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