Senior Principal Investigator at New England Biolabs and Honorary Professor at Durham University. Views my own. He/him.
Joined September 2020
- Tweets 217
- Following 1,416
- Followers 1,843
- Likes 541
5 Photos and videos
Tim Blower retweeted
Phages invented sgRNAs before humans!!
Obviously, for mischief… 😈
Loved seeing this story unfold!
biorxiv.org/content/10.64898…
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Tim Blower retweeted
NEB researchers systematically screened 186 MazF homologs, identifying >130 active endoribonuclease with diverse sequence preferences. Read more about how Tth-MazF1 can be a powerful tool for RNA analysis in Nucleic Acids Research: doi.org/10.1093/nar/gkag338
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Tim Blower retweeted
Rejection is part of science. So is resilience. 🔬
@BlowerLab and @CJStewart7 share how setbacks helped shape their careers. We don't talk about this enough.
🔁Please repost and share your own stories of defeat or bouceback. Break the stigma!
lister-institute.org.uk/news…
ALT Head and shoulder photos of Chris Steward (left) and Tim Blower (right). Both are wearing dark navy jackets and navy ties against blurred backgrounds.
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Mar 20
Postdoc position now open in my lab at New England Biolabs. Focus is on exploring phage defence systems through biochem and structural biology. @NEBiolabs provides an academic research environment with the freedom of industry. Please take a look! 🤓🧫🧬 tinyurl.com/49phcyh6
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17 Nov 2025
Rel/Par superfamily toxins have yet another activity - trimming off the 16S rRNA to kill tuberculosis. Thanks again to wonderful collab with @GenevauxPierre and team, out today shorturl.at/Rm8N4 @DurBiol @NEBiolabs @izaakbeck 🤓🎊🎉
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4 Nov 2025
Looking for great PhD candidates! Excited to collab with Prof Mark Szczelkun at Bristol UK, studying MADS phage defence. This will be a CASE studentship including research visits to New England Biolabs HQ in MA, USA 🤓 @NEBiolabs shorturl.at/KZGup deadline 3rd Dec
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14 Jul 2025
RptR is a new addition to the growing collection of phage defence-associated transcriptional regulators. Congrats to @YugengZ @TangLabOxford @_MarionSchuller @IvanAhelLab and thank you, it was a pleasure to help out the study! @NEBiolabs. academic.oup.com/nar/article…
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23 Jun 2025
Latest BREX story from the lab - turns out there is a nuclease after all! Congrats to Jenny Readshaw and the whole team, including wonderful collabs Barry Stoddard, Brett Kaiser and @DarrenSmithdx. @NAR_Open @NEBiolabs @DurBiol academic.oup.com/nar/article…
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Tim Blower retweeted
21 May 2025
We are delighted to host Professor Tim Blower @BlowerLab as keynote speaker to our MID symposium
@WarwickLifeSci
Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to
@CRodriguesLab
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Tim Blower retweeted
4 Apr 2025
For those of you who approached me at @MicrobioSoc #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!
24 Jan 2025
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
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13 Feb 2025
The lab is now up and running at New England Biolabs @NEBiolabs! I'm looking for a postdoc to study phage defence systems. If you'd like the academic freedom to publish but the resources of industry, then take a look 🤓😃 neb.wd5.myworkdayjobs.com/en…
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13 Feb 2025
The post will be based in Ipswich, MA, north of Boston. Non-US citizens welcome (if eligible for a J-1 visa). The focus will be on basic research leading to publications. We provide an academic research and training environment, with >20 research labs.
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24 Jan 2025
Super opportunity to join Giusy in Glasgow!
24 Jan 2025
🚨We are hiring! A MRC-funded PDRA position to study novel anti-phage systems & their evolutionary dynamics in P. aeruginosa, in collaboration with @friendlymicrobe. If you are passionate about phage-bacteria interactions & evolution, apply now ! tinyurl.com/bddz4z44
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Tim Blower retweeted
16 Dec 2024
The final version of our Serratia paper is now out! Congrats to @TomCX99 and (X-less) Suraj, and a big thank you to @BlowerLab and @StephenRG97. tinyurl.com/3vnyvufa
29 Jan 2024
New pre-print from the lab, led from (for now Twitter-less) star-RA Tom Cummins. If you did receive his PhD application, you do not want to miss this chance, Tom is a star!
As always, fun collaboration with the amazing @BlowerLab and @StephenRG97
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12 Dec 2024
RT @GiusyM1990: Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the Uni…
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Tim Blower retweeted
30 Nov 2024
Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date).
@JohnInnesCentre @DurhamU34989 @MCB_UJ
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Thrilled to share my latest postdoc paper published in
@NatureComms
NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors,
@GenevauxPierre
@BlowerLab
@ONeyrolles
rdcu.be/dZle4
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Tim Blower retweeted
5 Nov 2024
When experiments don’t work... build a phage costume! 🎃
Happy PHAGEOWEEN!!! 👻🧬#Teamwork
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Tim Blower retweeted
24 Oct 2024
journals.asm.org/doi/10.1128…
Our thoughts on how toxins bound to TAs are activated: via conformation changes, not by selective degradation of ATs by a protease (makes little sense since both are structured). Remarkable insights determined by studying various TAs as they inhibit phage.
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Tim Blower retweeted
6 Sep 2024
Researchers @blowerlab and colleagues use biochemistry, biophysics, and crystallography to characterize a mechanism of antitoxin induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis
nature.com/articles/s41467-0…
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