CSHL Press publishes celebrated books, journals and other media in the fields of genetics, cell and molecular biology.

Joined May 2010
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How do cells control protein production? This review from the #RNASpecialIssue explores how Ribo-seq and live single-molecule imaging are bringing together genome-wide and real-time views of mRNA translation. Access now: bit.ly/4mjjI8B
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Nancy Wexler has spent a lifetime advancing our understanding of Huntington’s disease. In this moving New York Times profile, she reflects on the personal and scientific journey behind her new memoir, "My Life, My Science", published by CSHL Press. bit.ly/wexlernytimes
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How do researchers make sense of data from millions of cells? This #RNASpecialIssue review explores how AI and machine learning uncover patterns in single-cell RNA sequencing data, revealing new insights into cell identity, function, and disease: bit.ly/4eboUJF
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🌟G&D SPOTLIGHT 🌟 G&D is pleased to present a collection of recent articles on RNA biogenesis and regulation. Learn more about small RNA biogenesis, target-mediated miRNA degradation, RNA splicing, ribonucleoprotein granules, and more. ➡️ genesdev.cshlp.org/site/misc…
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How can poly(A) site usage be controlled? This review from the #RNASpecialIssue examines strategies to modulate cleavage and polyadenylation sites, highlighting applications in studying alternative polyadenylation and developing new therapeutic approaches. bit.ly/4sthgOt
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The new issue of @genomeresearch is now live. Follow the link to new research on allele-specific splicing in Alzheimer's disease, tissue-specific gene regulation by vitamin B, and more! tinyurl.com/Genome-Res-36-6
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Can we map miRNAs and their targets in brain tissue? Current spatial transcriptomics methods can't simultaneously measure miRNAs and their target 3′UTRs. This #RNASpecialIssue review explores the challenge and emerging solutions: bit.ly/4sv5Dq1 #RNABiology #MicroRNA
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RNA function is defined by its interactions. This review from the #RNASpecialIssue highlights new CLIP-based methods to map protein–RNA and RNA–RNA contacts, advancing reconstruction of RNA interaction networks at transcriptome scale. bit.ly/41KDfWl
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How well can machine learning predict RNA secondary structure? This review in the #RNASpecialIssue examines current approaches—from deep learning to hybrid models—while exploring the field’s “generalization crisis” and the rise of RNA foundation models. bit.ly/4spSj6s
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How well do deep learning models generalize in RNA secondary structure prediction? This Perspective from the #RNASpecialIssue explores the “generalization gap” limiting current methods and how AI is reshaping RNA structure prediction. bit.ly/4dx1lec #Bioinformatics
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Nanopore direct RNA sequencing is reshaping epitranscriptomics — enabling direct detection of RNA modifications and RNA damage across entire transcriptomes with long-read sequencing. New review from the #RNASpecialIssue: bit.ly/3POaGo9 #RNA #Epitranscriptomics #Nanopore
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🚨 NEW ISSUE ALERT!!! 🚨 New Research articles online now at Genes & Development! Also in this issue, an Outlook on target-directed miRNA degradation, and a Review discussing the recent advances in optogenetics! Click here to learn more: ➡️ genesdev.cshlp.org/content/4…
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What’s next for RNA biology at system scale? In this #RNASpecialIssue editorial, the editors frame a shift toward quantitative, integrative approaches, highlighting advances in measuring, modeling, and ultimately manipulating RNA across biological systems. bit.ly/41hv9UJ
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We're pleased to feature a recent Special Issue of RNA showcasing advances in system-level RNA biology—from epitranscriptomics and RNA damage to deep learning–driven structure prediction and beyond. A strong snapshot of where the field is heading. bit.ly/RNAspecialissue2026
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The new issue of @genomeresearch is now live. Follow the link to new research on somatic mutant alleles in bulk tumor samples, honey bee gut microbiota, and more! tinyurl.com/Genome-Res-36-4
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The new issue of @genomeresearch is now live. Follow the link to new research on chromosome engineering in 8p syndrome, convergent evolution in arid rodents, and more! tinyurl.com/Genome-Res-36-3
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Genetically vulnerable to Huntington’s Disease, Nancy Wexler devoted her life to ground-breaking work that revealed the HD mutation and produced a test for susceptibility. Now living with HD, Nancy Wexler has a powerful autobiography published by CSHL Press: "My Life, My Science: Pursuing a Cure for Huntington’s Disease". Pre-order from Amazon at amz.cx/3c1w
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The new issue of @genomeresearch is now live. Follow the link to new research on transposable elements in pancreatic cancer, genomic evolution in living fossils, and more! tinyurl.com/Genome-Res-36-2
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The new issue of @genomeresearch is now live. Follow the link to new research the 3D genome organization in breast cancer, assisted reproductive technology mutation rate, and more! tinyurl.com/Genome-Res-36-1
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