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Genes & Development @GenesDev
Joined July 2009
  • Tweets 2,087
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  • Followers 8,681
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Genes & Development@GenesDev
Jun 1
🚨 NEW ISSUE ALERT!!! 🚨 New Research articles online now at Genes & Development! Also in this issue, an Outlook on organ-specific cell fate, and a Perspective discussing all things PARP14! Click here to learn more: ➡️ genesdev.cshlp.org/content/4…
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RESOURCE/METHODOLOGY: Neural stem cell epigenomes and fate bias are temporally coordinated during mouse cortical development By Shapira et al., Amos Tanay, and Boyan Bonev ➡️ genesdev.cshlp.org/content/4… @yonatan1shapira @WeizmannScience @Bonev_Lab @epigeneticsHMGU @HelmholtzMunich
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📽️ G&D Tapes 📽️ G&D Author, Yu-Han Yeh, talks about the role of histone chaperone DAXX in histone replacement during spermatogenesis. In this issue of #genesdev: ➡️ genesdev.cshlp.org/content/4… @ucdavis #histone #germline #epigeneticinheritence
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RESEARCH COMMUNICATION: DAXX directs dual modes of H3.4-to-H3.3 histone replacement in the male germline By Yeh et al. and Satoshi Namekawa ➡️ genesdev.cshlp.org/content/4… @ucdavis #histone #germline #epigeneticinheritence
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G&D's Editor-In-Chief, Andrew Dillin, will be attending the GRC for Systems Aging in Maine. If you’d like to chat about publishing your work with #genesdev, feel free to reach out to dillin@berkeley.edu @GenesDev @dillinlab @GordonConf
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RESEARCH PAPER: The eukaryotic homology search complex distorts donor DNA structure to probe for homology By Woodhouse et al., Michelle Wang, and Brooks Crickard ➡️ genesdev.cshlp.org/content/4… @CornellCALS @Cornell #DNArepair #homology #opticaltweezers
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RESEARCH PAPER: The microprotein SMIM26 connects metabolite transporters of the outer and inner mitochondrial membranes and is essential for respiratory chain function By Heizler et al. and Gunter Meister ➡️ genesdev.cshlp.org/content/4… @HeizlerKevin #mitochondria #lncRNA #metabolism
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RESEARCH PAPER: A dual role for cGAS in shaping cellular and organismal responses to genomic instability By Bergman et al. and Itamar Harel ➡️ genesdev.cshlp.org/content/4… @ItamarHarel @HebrewU @GeneticsDepart1 #aging #genome #DNArepair #killifish
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G&D's Editor-In-Chief, Andrew Dillin, will be at the University of Wisconsin-Madison for the MAPSS DevCell meeting. If you’d like to chat about publishing your work with #genesdev, feel free to reach out to dillin@berkeley.edu @GenesDev @dillinlab
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G&D's Executive Editor, Eric Sawey, is at the EACR 2026 Congress: Innovative Cancer Science in Budapest #EACR2026. If you'd like to chat about publishing your work with #genesdev, connect with him there or via email at sawey@cshl.edu
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🌟G&D SPOTLIGHT 🌟 G&D is pleased to present a collection of recent articles on RNA biogenesis and regulation. Learn more about small RNA biogenesis, target-mediated miRNA degradation, RNA splicing, ribonucleoprotein granules, and more. ➡️ genesdev.cshlp.org/site/misc…
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G&D's Executive Editor, Eric Sawey, will be attending the EACR 2026 Congress: Innovative Cancer Science in Budapest next week #EACR2026. If you'd like to share your work with us or learn about the journal, connect with him there or via email at sawey@cshl.edu
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Genes & Development retweeted
Timothy En Haw Chan@timothykoala
May 31
🚥🧬How do cells sense external signals and turn them into lasting responses? We discovered that TGF-β induces the recruitment of MLL4 (KMT2D), which works together with the transcription factor JUNB to form a positive feed-forward loop.
Genes & Development@GenesDev
May 28
🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: MLL4/KMT2D histone methyltransferase and JUNB cooperate in a feed-forward loop to support AP-1-dependent TGF-β signaling By Chan et al. and and Marc Timmers ➡️ ow.ly/9v3H50Z4Uh6 #epigenetics #transcription #histone #TGFβ
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📽️ G&D Tapes 📽️ G&D Author, Lucas Unger, tells us about an auto-regulatory loop between HNF1A and Hedgehog signaling that dictates stem cell lineage specification. In this issue of #genesdev: ➡️ genesdev.cshlp.org/content/4… @chera_lab @medofak_uib #stemcell #development #hedgehog
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RESEARCH PAPER: Defective HNF1A hinders GLI3 processing favoring duodenal versus pancreatic fate, thus leading to intestinal elongation in vivo By Unger et al. Luiza Ghila, and Simona Chera ➡️ genesdev.cshlp.org/content/4… @chera_lab @medofak_uib #stemcell #development #hedgehog
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🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: Evolutionarily conserved spliceosome–exosome pathway in nuclear mRNA surveillance By Abbas et al. and Elena Conti ➡️ ow.ly/LR8u50Z5MsI @MPI_Biochem #RNAdecay #splicing #mRNA #RNAsurveillance
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🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR By Yoon et al. and Satya Prakash ➡️ ow.ly/l24j50Z5LM6 @utmbhealth #DNAreplication #translesionsynthesis #genomestability #DNArepair
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🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: Cleavage of the RNA polymerase II general transcription factor TFIIB tunes transcription during stress By Gulyas et al. and Britt A. Glaunsinger ➡️ ow.ly/j5kI50Z5Lka @UCBerkeley @hhmi_science #transcription #stress #cancer #virus
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🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: DDX3X-mediated translation of structured cardiac mRNAs is essential for female heart development By Mason et al. and and Frank Conlon ➡️ ow.ly/PBY350Z4UqY #cardiacdevelopment #sexdifferences #Xlinked #translation
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🆕 ADVANCE ONLINE 🆕 RESEARCH PAPER: MLL4/KMT2D histone methyltransferase and JUNB cooperate in a feed-forward loop to support AP-1-dependent TGF-β signaling By Chan et al. and and Marc Timmers ➡️ ow.ly/9v3H50Z4Uh6 #epigenetics #transcription #histone #TGFβ
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