Research center working towards #precisiononcology. Ask us about generation, characterization & applications of patient-derived models (PDX, organoids, cells).
Congrats Maria on a fantastic undergrad thesis defense in #glioblastoma functional precision medicine at CPDM. Way to get honors! We were so proud and happy to have you with us & mentors Kin Hoe Chow, Sonam Bhatia, Smitha Yerrum and @KeithLigon5@NeurosciBU#gpn@BU_Tweets#fpm
Great to see #fpm growing this year to have a whole session at #AACR2023 with exciting prospective trials results and other studies from @CancerModels collaborator @DrTonyLetai as well as Pam Becker and @AlanaWelm @PhilippStaber
President Biden said, "The goal is to cut cancer death rates by at least 50% in the next 25 yrs." This reignited Cancer Moonshot in Boston last September. Register for #SOP23 & explore the opportunities & barriers to realizing this ambitious goal. massbio.org/events/listing/2…
Mini-organs attract big pharma go.nature.com/3Ef6jK5
Hans Clevers, head of Pharma Research & Early Development at Roche, discusses the role for organoids in drug discovery and development in this new interview
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Dana-Farber Center for Patient Derived Models retweeted
Join us *THIS WEDNESDAY* March 8th at 11:30 AM EST / 8:30 AM PST for our next seminar featuring @ElementoLab from @WCMEnglanderIPM presenting "From reading genomes to patient avatars - the future of personalized medicine".
Link/Info available here: sfpm.io/seminars
Our new paper w/BMS shows CAFs are the source of EMT signal in most cancers --> data from 333 PDX models/11 tumor types from @DanaFarber@CancerModels. Thx Michael Tolstorukov's DFCI I/A team, @Novartis, and David Weinstock for helping CPDM make the models available to the science community. @bmsnewsnature.com/articles/s41598-0…rdcu.be/c6AQl
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Dana-Farber Center for Patient Derived Models retweeted
Attending #AACR23 in Orlando this year? Save the date and Join us for a fun night of food, drinks, and networking. This is a great opportunity to learn more about the SFPM, meet the board, share ideas and even become a member! RSVP on sfpm.io
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Dana-Farber Center for Patient Derived Models retweeted
On average, it takes more than 10 years and billions of dollars to develop a new drug.
Incorporating AI into the drug development pipeline could help create cheaper pharmaceuticals faster. trib.al/nB9fa7X
If an ASO lowers target RNA 50% in bulk brain tissue, is it 50% in all cells or 100% in half? Are cell types all impacted equally? Does CSF reflect neuronal target engagement?
We did single-cell seq in ASO-treated mice & NHPs to find out doi.org/10.1101/2023.02.14.5…
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SFPM Seminar tomorrow: Travera CEO Cliff Reid will present on their novel rapid therapy guidance testing based on single cell mass. #precisionmedicine#oncologysfpm.io/seminars