Editorial team of Nature Reviews Drug Discovery.

Joined April 2009
2,432 Photos and videos
For readers interested in the design of next-generation small-molecule kinase inhibitors, here's a comprehensive review nature.com/articles/s41573-0… rdcu.be/fn0n5
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Upcoming FDA approval decisions in Q3 2026 nature.com/articles/d41573-0… Decisions on the US approval of new drugs include the kinase inhibitor zidesamtinib for non-small-cell lung cancer, which is being acquired by GSK in their $10.6 billion deal for Nuvalent this week
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Antiviral peptide nabs FDA approval for hepatitis delta virus infection nature.com/articles/d41573-0… Gilead’s bulevirtide is the first treatment for the potentially fatal infection
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The therapeutic potential of orphan adhesion G-protein-coupled receptors nature.com/articles/s41573-0… rdcu.be/fnAyg This Review in the June issue discusses disease roles of adhesion GPCRs, as well as strategies and compounds for therapeutically targeting them
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Evolution of the psoriasis therapy landscape nature.com/articles/d41573-0… This new article analyses the pipeline of drugs for psoriasis and their market impact, highlighting the growing importance of oral therapies
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For readers interested in next-generation GLP-1-based therapies for diabetes, obesity and more, here's a review nature.com/articles/s41573-0… rdcu.be/fnl3W
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Nature Reviews Drug Discovery retweeted
Jun 8
Eli Lilly has already established that its next-generation obesity drug can lead to highly rapid weight loss. Researchers disclosed new data that provide more details on the safety and tolerability of the closely-watched therapy. trib.al/ZbFlwbK
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Analysis of a decade of post-authorisation studies for medicines approved by the EMA nature.com/articles/d41573-0… This article analyses studies that have been requested by the EMA in order to provide data on the quality, safety or efficacy of medicines after approval
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For readers interested in synthetic lethality in cancer drug discovery, here's a review rdcu.be/fnaNw nature.com/articles/s41573-0…
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A guide to effective drug development through nonprofit models nature.com/articles/d41573-0… Patient organizations are reshaping rare disease drug development. Based on a survey, interviews and experience, this article discusses how to direct resources toward drug development goals
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Our June issue is live! Read about the therapeutic potential of orphan GPCRs, wearable technologies in clinical trials for drug development, a renaissance in targeting the PI3K/AKT/mTOR pathway and more here nature.com/nrd/volumes/25/is…
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Towards mRNA therapeutics 2.0 nature.com/articles/s41573-0… This new Review discusses progress and insights from clinical studies on mRNA-based drugs, including enzyme replacement therapies, cancer immunotherapies, genome-modifying therapies and immune cell reprogramming therapies
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Therapeutic and prophylactic strategies for Ebola caused by Bundibugyo virus nature.com/articles/d41573-0… This new article argues that the ongoing Ebola outbreak should be a turning point for moving R&D towards species-inclusive and broadly applicable filovirus countermeasures
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Better data for better medicines: a path to data-driven medicines regulation nature.com/articles/d41573-0… This new Comment article highlights how the EU medicines regulatory system is becoming more data-driven @EMA_News
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For readers interested in kinase inhibitors in cancer and beyond, this Review covers the expanding toolkit for kinase modulation, including allosteric modulators and proximity-inducing molecules such as molecular glues nature.com/articles/s41573-0… rdcu.be/fl5H5 #ASCO26
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For readers interested in cancer immunotherapy, this article reviews the clinical landscape for agonistic antibodies as immunotherapies and discusses how mechanistic insights should broaden their clinical application nature.com/articles/s41573-0… rdcu.be/flSve #ASCO26
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For readers interested in cyclin-dependent kinase inhibitors in cancer, here's a comprehensive review discussing their progression beyond CDK4/6 inhibitors for breast cancer nature.com/articles/s41573-0… rdcu.be/flRPL #ASCO26
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