How to specifically select a protein from one side of the membrane and to transport it on the other side ? That's what we will love to understand. #T6SS #T9SS

Joined July 2015
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Happy to share the last publication of @bTaillefer_, showing that #T6SS heterogeneity is an attenuation strategy to optimizes the trade-off between competitive killing and survival. @PLOSBiology journals.plos.org/plosbiolog…
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Happy to share the last work of Jonas @JonasDesjardins, identifying and characterizing a novel Rhs NAD(P) glycohydrolase delivered by the #T6SS of the major cosmetic contaminant, Pluralibacter gergoviae. jbc.org/article/S0021-9258(2…
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Cascales Lab retweeted
Postdoc opening in my lab @HumboldtUni! Join our Einstein Foundation-funded collaboration with the Hebrew University of Jerusalem on T3SS, spatial RNA localization, imaging & bacterial cell biology. 📅 Apply by 2 June 2026 🔗 hu.berlin/T3SSjob #Postdoc #Microbiology
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T2SS ? T4SS ? CDI ? T6SS ? T7SS ? NO ! The #T9SS is also involved in interbacterial competition !! @CurrentBiology Great work by Maelle Paillat @maelle_paillat under the supervision of Thierry Doan @doan_thierry sciencedirect.com/science/ar…
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Cascales Lab retweeted
Glad to share our latest review on the diversity of defense mechanisms against the T6SS! “Anti-type VI tactics: bacterial defenses against type VI secretion system attacks” is available in Trends in Biochemical Sciences right now. @CascalesLab @jpcotelab authors.elsevier.com/c/1msKv…
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Very happy that our work on the T6SS ADP-ribosylcyclase toxin made the Cover at JBC @jbiolchem ! Congratulations Julius @MartinkusJM for designing this Cover ! @DukasJu @LaurentTerradot
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Happy to share the last paper form the lab: "Specialized shuttle proteins recognize T9SS signals and target effectors to their final destinations". Great work by @maelle_paillat, led by @doan_thierry in collaboration with @StephaneAUDEBE1 @LISM_CNRS_AMU rdcu.be/eP5Xe
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Applications closing tonight (midnight French time) !!! Still a few hours to apply !!
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Doctor…
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Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Doctor…

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We will have soon an Open position for a PhD thesis position to work on bacterial secretion systems ! Stay tuned !!
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We have an Open position !! Either at the Engineer or post-doctoral level, to work on filamentous phages. Collaboration between @l_houot and @doan_thierry To apply at the E level: emploi.cnrs.fr/Offres/CDD/UM… To apply at the post-doc level: emploi.cnrs.fr/Offres/CDD/UM…

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Cascales Lab retweeted
📢 Job alert! The Structural Microbiology Laboratory (albesalab.org/) has two new openings! We are looking for a PhD student and a Research Technician to join our team. Project: "Structure-function studies of Type VI secretion system toxins". biofisika.org/en/join-us

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Cascales Lab retweeted
The application deadline has been extended for a postdoc position in our lab until August 22. Please enquire/apply if you are interested in ADP-ribosylation, ubiquitination, genome stability or immunity. my.corehr.com/pls/uoxrecruit…

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We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested: emploi.cnrs.fr/Offres/CDD/UM…

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Cascales Lab retweeted
Post-doc fellowship available in my lab at Umeå University, Sweden🇸🇪. The project is focused on structure and function of lipoprotein transports systems in Gram-negative bacteria. Read more and apply here: umustipendie.varbi.com/en/wh… Closing date - 10th of august 2025.
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Le LISM (lism.imm.cnrs.fr) propose une mobilité NOEMI pour travailler sur des assemblages de l'enveloppe bactérienne. Profil microbiologie, bio mol, avec une envie de faire de la biochimie, de la microscopie ou de la bio cell ! Rejoignez une unité dynamique !!

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We moved to BlueSky. Please join us and follow us there ! cascaleslab.bsky.social

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