Bacterial geneticist @HumboldtUni studying assembly and function of a fascinating nanomachine - the bacterial flagellum

Joined December 2016
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Postdoc opening in my lab @HumboldtUni! Join our Einstein Foundation-funded collaboration with the Hebrew University of Jerusalem on T3SS, spatial RNA localization, imaging & bacterial cell biology. 📅 Apply by 2 June 2026 🔗 hu.berlin/T3SSjob #Postdoc #Microbiology
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PhD opening in my lab @HumboldtUni Join our DFG SPP 2389 project on bacterial biofilms & multicellularity. Study how F-pili conjugation shapes biofilms using genetics, microfluidics & 3D imaging. 📅 Apply by 3 June 2026 🔗 hu.berlin/SPP2389-PhD #PhD #Microbiology #Biofilms
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Marc Erhardt retweeted
Congratulations to first author @AritzRoa for his amazing work on how T4 delivers its genome and blocks other phages from injecting theirs 🥳 Check out his beautiful movie📽️ Thanks to all authors and collaborators MLNielsen and @AHarms485 tinyurl.com/2kvva646 #cryoEM #phage
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Marc Erhardt retweeted
24 Nov 2025
#MicrobiologyMonday: The bacterial flagellum is built through a hierarchical assembly process and powered by a dynamic motor capable of astonishing speeds. What's new in our understanding of these complex nanomachines? Find out in #MMBRJournal: asm.social/2HB
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Marc Erhardt retweeted
13 Oct 2025
A beautiful example of evolutionary innovation: Bacterial chemoreceptor was "reprogrammed" in pathogenic E. coli to control expression of flagellar genes instead of signalling through the chemotaxis pathway. embopress.org/doi/full/10.10…
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Marc Erhardt retweeted
Out Now! The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation bit.ly/4nqcNe9 #Microbiology #Bacteria #Flagellum
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"The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation" Now published @NatureMicrobiol 🥳! rdcu.be/eugWM

I'm excited to share the newest preprint of the lab... the structure of the complete extracellular flagellum, our most favourite bacterial nanomachine! biorxiv.org/content/10.1101/… A result of a very productive collaboration with @BergeronLab and @BeebyLab !
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Marc Erhardt retweeted
Cold Spring Harbor Laboratory - absolutely humbled by the beauty of this place and the ubiquitous spirit of the Delbrück "phage group" era 🧬🌊🦪
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Marc Erhardt retweeted
Exited to share our preprint on the structure of a Salmonella contractile injection system 🥳 Wonderful work by first author @Rooshanie Ejaz and @CloudyKielkopf, @freddie__martin, @HangryHobbit, @RebrovaEva, great collab with @Salmo_Lab @UCPH_CPR #cryoem shorturl.at/QHLpm

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Marc Erhardt retweeted
And here it is, the completed BASEL collection finally published as early access in @PLOSBiology - see the thread for more details. 🤗🧬🎣
🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵
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New #biorxiv preprint I'm quite excited about. We show that the #T3SS of the #flagellum secretes proteins at a rate of 10,000 amino acids per second, resulting in optimized flagellum growth and energy consumption. biorxiv.org/content/10.1101/…
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Marc Erhardt retweeted
Join us and @Salmo_Lab to explore phage-bacteria interactions, with a strong focus on microscopy techniques. Looking for a motivated PhD student! 🔬 Interested? Apply here 👉 [nature.com/naturecareers/job…] 🔄 Please re-share to spread the word!
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Interested in anti-bacteriophage defense systems? We have an open PhD position in cell biology of bacteria and bacteriophages: nature.com/naturecareers/job…
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Marc Erhardt retweeted
With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! 🤯 @imperialcollege @FlemingCentre tinyurl.com/3byyaeh2

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Marc Erhardt retweeted
30 Jan 2025
Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems CARDs are essential for caspase recruitment in inflammasome activation. We now find them in bacterial immune systems Congrats @TanaWein! Thanks Kranzusch lab! tinyurl.com/CA88DD
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Marc Erhardt retweeted
Internationales Forschungsteam beschreibt erstmals die Struktur und Funktionsweise des Zorya-Systems, eines hochspezialisierten antiviralen Schutzmechanismus gegen Bakterien nature.com/articles/s41586-0… @Salmo_Lab @__jphilipp Bild: Frederick J.O. Martin/ Universität Kopenhagen
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RT @HumboldtUni: 🦠 Neues bakterielles #Immunsystem entschlüsselt: Ein internationales Forschungsteam um @Salmo_Lab & @__jphilipp der #Humbo…
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Marc Erhardt retweeted
Thrilled to share that our collaborative work, led brilliantly by @HaidaiHu, is now published in @Nature! Huge thanks to the incredible @NMITaylorLab team - it was a joy to work with you. Grateful to @Salmo_Lab, @SimonJacksonNZ, and @AHarms485 for their invaluable contributions!
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
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Our work describing the structure and mechanism of the Zorya anti-phage defense system is finally out @Nature! Led by @HaidaiHu and @__jphilipp in a wonderful collaboration with @NMITaylorLab, @SimonJacksonNZ, @AHarms485 et al.! nature.com/articles/s41586-0…
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Marc Erhardt retweeted
11 Dec 2024
Evolutionary necessity for immune innovation harnessed components of the bacterial flagellar motor into a wild defense system - Zorya One of the most intriguing and sophisticated bacterial defense systems out there Congratulations Nicholas Taylor and colleagues!
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
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