very interesting work @doc_jlmeier A chemoproteomic portrait of the oncometabolite fumarate nature.com/articles/s41589-0…

Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability | Nature Neuroscience nature.com/articles/s41593-0…

There are intriguing preliminary studies out there (DNA methylation/psychological stress), but, as with most #epigenetic association studies, there’s a major deficit in interpretability, and a need to move to much more definitive (expensive, complex) projects.

X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels (Stem Cell Rep) bit.ly/2SOE6jp bit.ly/2SOE6jp

Our recent paper describes genome-wide DNA methylation and transcriptomic profiles in the lifestyle strategies and asexual development of a forest fungal pathogen, doi.org/10.1080/15592294.201…

New in Pubmed: "Altered DNA Methylation in the Developing Brains of Rats Genetically Prone to High Versus Low Anxiety." bit.ly/2HJfWFQ

Estrogen down regulates COMT transcription via promoter DNA methylation in human breast cancer cells.: CatecholOmethyltransferase COMT acts as a 'gatekeeper' to prevent DNA damage during estrogen metabolism. Both experimental and epidemiological studies… bioportfol.io/Qxbxxc

Dynamics of DNA Methylation and DNMT Expression During Gametogenesis and Early Develo…|Mar Biotechnol (NY)•Wang S pubmed.com/30680591

DNA methylation and histone H1 cooperatively repress transposable elements and aberrant intragenic transcripts biorxiv.org/cgi/content/shor… #biorxiv_genetic

Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affect burst size, whereas enhancers mainly affect burst frequency nature.com/articles/s41586-0… @nature

Just saw (my former mentor) Steve Jacobsen present this work at #MPIEpigenetics2018, hot off the presses at Science. DNA methylation based-mechanism for gene activation. Great stuff!! science.sciencemag.org/conte…

DNA methylation profiles clearly mirror genetic and geographic structure across blood samples from five of the six extant species of the baboon genus *Papio* academic.oup.com/mbe/advance…

Really nice new paper from my colleague @GJCVeenstra MTF2 as a recruiter of PRC2 to unmethylated CpG islands Some very interesting analysis of consequences of helical shape properties and their influence on protein-DNA interaction x.com/NatureGenet/status/100…

Interested in studying CpG islands and gene regulation using synthetic approaches? If so, a Post-doc position is now available in my lab for a creative and motivated candidate to do just that! recruit.ox.ac.uk/pls/hrisliv… Please Retweet